6UAN
 
 | | B-Raf:14-3-3 complex | | 分子名称: | 14-3-3 zeta, Serine/threonine-protein kinase B-raf | | 著者 | Kondo, Y, Ognjenovic, J, Banerjee, S, Karandur, D, Merk, A, Kulhanek, K, Wong, K, Roose, J.P, Subramaniam, S, Kuriyan, J. | | 登録日 | 2019-09-11 | | 公開日 | 2019-09-25 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
Science, 366, 2019
|
|
7SZ7
 | | Cryo-EM structure of the extracellular module of the full-length EGFR bound to TGF-alpha. "tips-juxtaposed" conformation | | 分子名称: | Epidermal growth factor receptor, Transforming growth factor alpha | | 著者 | Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. | | 登録日 | 2021-11-25 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
|
|
7SZ1
 | | Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-separated" conformation | | 分子名称: | Epidermal growth factor, Epidermal growth factor receptor | | 著者 | Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. | | 登録日 | 2021-11-25 | | 公開日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
|
|
7SYD
 | | Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF "tips-juxtaposed" conformation | | 分子名称: | Epidermal growth factor, Epidermal growth factor receptor | | 著者 | Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. | | 登録日 | 2021-11-24 | | 公開日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
|
|
7SZ5
 | | Cryo-EM structure of the extracellular module of the full-length EGFR bound to TGF-alpha "tips-separated" conformation | | 分子名称: | Epidermal growth factor receptor, Transforming growth factor alpha | | 著者 | Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. | | 登録日 | 2021-11-25 | | 公開日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
|
|
7SYE
 | | Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF. "tips-separated" conformation | | 分子名称: | Epidermal growth factor, Epidermal growth factor receptor | | 著者 | Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. | | 登録日 | 2021-11-24 | | 公開日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
|
|
7SZ0
 | | Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-juxtaposed" conformation | | 分子名称: | Epidermal growth factor, Epidermal growth factor receptor | | 著者 | Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. | | 登録日 | 2021-11-25 | | 公開日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
|
|
5NLV
 | | Brag2 Sec7-PH (390-763) | | 分子名称: | IQ motif and SEC7 domain-containing protein 1 | | 著者 | Nawrotek, A, Cherfils, J. | | 登録日 | 2017-04-05 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5NLY
 | | Brag2 Sec7-PH (390-763), P212121 | | 分子名称: | IQ motif and SEC7 domain-containing protein 1, PHOSPHATE ION | | 著者 | Nawrotek, A, Cherfils, J. | | 登録日 | 2017-04-05 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
