3CQZ
 
 | | Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin | | 分子名称: | ALPHA-AMANITIN, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | | 著者 | Kaplan, C.D, Larsson, K.-M, Kornberg, R.D. | | 登録日 | 2008-04-03 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The RNA Polymerase II Trigger Loop Functions in Substrate Selection and is Directly Targeted by Alpha-Amanitin.
Mol.Cell, 30, 2008
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2YU9
 | | RNA polymerase II elongation complex in 150 mm MG+2 with UTP | | 分子名称: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2007-04-06 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
Cell(Cambridge,Mass.), 127, 2006
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8U9X
 | | STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Arjunan, P, Calero, G, Kaplan, C.D. | | 登録日 | 2023-09-20 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8U9R
 | | STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*AP*CP*GP*TP*CP*CP*CP*TP*CP*TP*CP*GP*A)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Arjunan, P, Calero, G, Kaplan, C.D. | | 登録日 | 2023-09-20 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | | 主引用文献 | Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
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2E2H
 | | RNA polymerase II elongation complex at 5 mM Mg2+ with GTP | | 分子名称: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-14 | | 公開日 | 2006-12-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2E2I
 | | RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-14 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2E2J
 | | RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP | | 分子名称: | 27-MER DNA template strand, 5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3', 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-14 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2NVQ
 | | RNA Polymerase II Elongation Complex in 150 mM Mg+2 with 2'dUTP | | 分子名称: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-13 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2NVX
 | | RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP | | 分子名称: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-13 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2NVZ
 | | RNA Polymerase II elongation complex with UTP, updated 11/2006 | | 分子名称: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-14 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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5C4X
 | | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | | 登録日 | 2015-06-18 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
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5C4J
 | | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | | 登録日 | 2015-06-18 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
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5C4A
 | | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Barnes, C.O, Calero, M, Malik, I, Saphr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | | 登録日 | 2015-06-17 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
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5C3E
 | | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | | 登録日 | 2015-06-17 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
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5C44
 | | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | | 登録日 | 2015-06-17 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | | 主引用文献 | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
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2NVT
 | | RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP | | 分子名称: | 5'-D(*GP*TP*AP*CP*TP*TP*G)-3', 5'-D(P*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-13 | | 公開日 | 2006-12-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2NVY
 | | RNA Polymerase II form II in 150 mM Mn+2 | | 分子名称: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-13 | | 公開日 | 2006-12-26 | | 最終更新日 | 2025-06-04 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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5D4D
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5D4C
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5D4E
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8UOQ
 | | Composite map of PIC_delta_TFIIK form2 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Yang, C, Murakami, K. | | 登録日 | 2023-10-20 | | 公開日 | 2024-10-23 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Transcription start site scanning requires the fungi-specific hydrophobic loop of Tfb3.
Nucleic Acids Res., 52, 2024
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8UOT
 | | Composite map of PICdeltaTFIIK form1 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Yang, C, Murakami, K. | | 登録日 | 2023-10-20 | | 公開日 | 2024-10-23 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Transcription start site scanning requires the fungi-specific hydrophobic loop of Tfb3.
Nucleic Acids Res., 52, 2024
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7K04
 | | Structure of TFIIH/Rad4-Rad23-Rad33/DNA in DNA opening | | 分子名称: | CALCIUM ION, DNA repair helicase RAD25, DNA repair helicase RAD3, ... | | 著者 | van Eeuwen, T, Min, J.H, Murakami, K. | | 登録日 | 2020-09-03 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (9.25 Å) | | 主引用文献 | Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
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7K01
 | | Structure of TFIIH in TFIIH/Rad4-Rad23-Rad33 DNA opening complex | | 分子名称: | DNA repair helicase RAD25, DNA repair helicase RAD3, General transcription and DNA repair factor IIH subunit SSL1, ... | | 著者 | van Eeuwen, T, Min, J.H, Murakami, K. | | 登録日 | 2020-09-02 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
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7M2U
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