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4DZV
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BU of 4dzv by Molmil
Complex of 4-alpha/beta bound to gp41-5
分子名称: 4-alpha/beta, GLYCEROL, gp41-5
著者Johnson, L.M, Mortenson, D.E, Yun, H.G, Horne, W.S, Ketas, T.J, Lu, M, Moore, J.P, Gellman, S.H.
登録日2012-03-01
公開日2012-05-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array.
J.Am.Chem.Soc., 134, 2012
4DZU
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BU of 4dzu by Molmil
Complex of 3-alpha bound to gp41-5
分子名称: 3-alpha, GLYCEROL, gp41-5
著者Johnson, L.M, Mortenson, D.E, Yun, H.G, Horne, W.S, Ketas, T.J, Lu, M, Moore, J.P, Gellman, S.H.
登録日2012-03-01
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array.
J.Am.Chem.Soc., 134, 2012
3O3Z
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BU of 3o3z by Molmil
Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to a gp41 NHR domain peptide
分子名称: Envelope glycoprotein gp160, GLYCEROL, chimeric alpha/beta peptide based on gp41 CHR domain sequence
著者Horne, W.S, Johnson, L.M, Gellman, S.H.
登録日2010-07-26
公開日2011-07-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
3O3X
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BU of 3o3x by Molmil
Crystal structure of gp41-5, a single-chain 5-helix-bundle based on HIV gp41
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, gp41-5
著者Horne, W.S, Johnson, L.M, Gellman, S.H.
登録日2010-07-26
公開日2011-07-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
3O43
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BU of 3o43 by Molmil
Complex of an alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5
分子名称: GLYCEROL, alpha/beta-peptide derived from gp41 CHR domain sequence, gp41-5
著者Horne, W.S, Johnson, L.M, Gellman, S.H.
登録日2010-07-26
公開日2011-07-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
3O40
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BU of 3o40 by Molmil
Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5
分子名称: CHLORIDE ION, GLYCEROL, NONAETHYLENE GLYCOL, ...
著者Horne, W.S, Johnson, L.M, Gellman, S.H.
登録日2010-07-26
公開日2011-07-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
3O42
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BU of 3o42 by Molmil
Complex of an alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, alpha/beta-peptide based on HIV gp41 CHR domain sequence, ...
著者Horne, W.S, Johnson, L.M, Gellman, S.H.
登録日2010-07-26
公開日2011-08-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Chimeric and Non-Chimeric Foldamer Mimics of the CHR Segment of HIV Protein gp41: Evidence for the Importance of a Large Binding Interface in Six-Helix Bundle Formation
To be Published
3O3Y
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BU of 3o3y by Molmil
A chimeric alpha+alpha/beta peptide based on the CHR domain sequence of gp41
分子名称: CHLORIDE ION, chimeric alpha+alpha/beta peptide based on the CHR domain sequence of gp41
著者Horne, W.S, Johnson, L.M, Gellman, S.H.
登録日2010-07-26
公開日2011-08-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Chimeric and Non-Chimeric Foldamer Mimics of the CHR Segment of HIV Protein gp41: Evidence for the Importance of a Large Binding Interface in Six-Helix Bundle Formation
To be Published
3G7A
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BU of 3g7a by Molmil
HIV gp41 six-helix bundle composed of a chimeric alpha+alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide
分子名称: ACETYL GROUP, Chimeric alpha+alpha/beta-peptide analogue of the HIV gp41 CHR domain, Envelope glycoprotein gp160, ...
著者Horne, W.S, Johnson, L.M, Gellman, S.H.
登録日2009-02-09
公開日2009-10-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
4NJ5
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BU of 4nj5 by Molmil
Crystal structure of SUVH9
分子名称: Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9, ZINC ION
著者Du, J, Patel, D.J.
登録日2013-11-08
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation.
Nature, 507, 2014
4RIL
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BU of 4ril by Molmil
Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction
分子名称: Alpha-synuclein
著者Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2023-09-20
実験手法ELECTRON CRYSTALLOGRAPHY (1.43 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
3F50
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BU of 3f50 by Molmil
HIV gp41 six-helix bundle composed of an alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide
分子名称: Envelope glycoprotein gp160, GLYCEROL, alpha/beta-peptide analogue of the HIV gp41 CHR domain
著者Horne, W.S, Gellman, S.H.
登録日2008-11-03
公開日2009-09-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3F4Z
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BU of 3f4z by Molmil
Trimeric helix bundle formed by an alpha/beta-peptide derivative of the HIV gp41 CHR domain
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, alpha/beta-peptide analogue of the HIV gp41 CHR domain
著者Horne, W.S, Gellman, S.H.
登録日2008-11-03
公開日2009-09-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3F4Y
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BU of 3f4y by Molmil
HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence
分子名称: Envelope glycoprotein gp160, Mutant peptide derived from HIV gp41 CHR domain
著者Horne, W.S, Gellman, S.H.
登録日2008-11-03
公開日2009-09-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
4ZNN
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BU of 4znn by Molmil
MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson's disease protein, alpha-synuclein residues 47-56
分子名称: Alpha-synuclein
著者Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S.
登録日2015-05-05
公開日2015-09-09
最終更新日2024-03-06
実験手法ELECTRON CRYSTALLOGRAPHY (1.41 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
6C3F
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BU of 6c3f by Molmil
AMYLOID FORMING PEPTIDE IYKVEI FROM TRANSTHYRETIN
分子名称: ILE-TYR-LYS-VAL-GLU-ILE, trifluoroacetic acid
著者Saelices, L, Sawaya, M.R, Eisenberg, D.S.
登録日2018-01-09
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C88
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BU of 6c88 by Molmil
STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
分子名称: GLYCEROL, VAL-ALA-VAL-HIS-VAL-PHE
著者Saelices, L, Sawaya, M.R, Eisenberg, D.S.
登録日2018-01-24
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
4RIK
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BU of 4rik by Molmil
Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77
分子名称: Alpha-synuclein
著者Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4TL5
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BU of 4tl5 by Molmil
Crystal Structure of Human Transthyretin Ser85Pro Mutant
分子名称: CHLORIDE ION, SODIUM ION, Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-28
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TKW
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BU of 4tkw by Molmil
Crystal Structure of Human Transthyretin Leu55Pro Mutant
分子名称: Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-27
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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BU of 4tl4 by Molmil
Crystal Structure of Human Transthyretin Val30Met Mutant
分子名称: Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-28
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4RP7
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BU of 4rp7 by Molmil
Structure of the amyloid-forming segment TIITLE from p53 (residues 253-258)
分子名称: TIITLE hexapeptide segment from p53, ZINC ION
著者Soriaga, A.B, Soragni, A, Eisenberg, D.
登録日2014-10-29
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.576 Å)
主引用文献A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4RP6
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BU of 4rp6 by Molmil
Structure of the amyloid-forming segment LTIITLE from p53 (residues 252-258)
分子名称: LTIITLE heptapeptide segment from p53
著者Soriaga, A.B, Soragni, A, Eisenberg, D.
登録日2014-10-29
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4TNE
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BU of 4tne by Molmil
Crystal Structure of Human Transthyretin Thr119Tyr Mutant
分子名称: GLYCEROL, Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-06-03
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLS
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BU of 4tls by Molmil
Crystal Structure of Human Transthyretin Glu92Pro Mutant
分子名称: GLYCEROL, PHOSPHATE ION, SODIUM ION, ...
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-30
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015

 

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