3NJ4
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![BU of 3nj4 by Molmil](/molmil-images/mine/3nj4) | Fluoro-neplanocin A in Human S-Adenosylhomocysteine Hydrolase | 分子名称: | (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Jeong, L.S, Lee, K.M, Hwang, K.Y, Choi, S, Heo, Y.S. | 登録日 | 2010-06-17 | 公開日 | 2011-05-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues. J.Med.Chem., 54, 2011
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8CU6
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![BU of 8cu6 by Molmil](/molmil-images/mine/8cu6) | Crystal structure of A2AAR-StaR2-S277-bRIL in complex with a novel A2a antagonist, LJ-4517 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3R,4R)-2-[(8P)-6-amino-2-(hex-1-yn-1-yl)-8-(thiophen-2-yl)-9H-purin-9-yl]oxolane-3,4-diol, Adenosine receptor A2a,Soluble cytochrome b562, ... | 著者 | Shiriaeva, A, Park, D.-J, Kim, G, Lee, Y, Hou, X, Jarhad, D.B, Kim, G, Yu, J, Hyun, Y.E, Kim, W, Gao, Z.-G, Jacobson, K.A, Han, G.W, Stevens, R.C, Jeong, L.S, Choi, S, Cherezov, V. | 登録日 | 2022-05-16 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A 2A Adenosine Receptor. J.Med.Chem., 65, 2022
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8CU7
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![BU of 8cu7 by Molmil](/molmil-images/mine/8cu7) | Crystal structure of A2AAR-StaR2-bRIL in complex with a novel A2a antagonist, LJ-4517 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3R,4R)-2-[(8P)-6-amino-2-(hex-1-yn-1-yl)-8-(thiophen-2-yl)-9H-purin-9-yl]oxolane-3,4-diol, Adenosine receptor A2a,Soluble cytochrome b562, ... | 著者 | Shiriaeva, A, Park, D.-J, Kim, G, Lee, Y, Hou, X, Jarhad, D.B, Kim, G, Yu, J, Hyun, Y.E, Kim, W, Gao, Z.-G, Jacobson, K.A, Han, G.W, Stevens, R.C, Jeong, L.S, Choi, S, Cherezov, V. | 登録日 | 2022-05-16 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A 2A Adenosine Receptor. J.Med.Chem., 65, 2022
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5ZNX
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![BU of 5znx by Molmil](/molmil-images/mine/5znx) | Crystal structure of CM14-treated HlyU from Vibrio vulnificus | 分子名称: | Transcriptional activator | 著者 | Park, N, Kim, S, Jo, I, Ahn, J, Hong, S, Jeong, S, Baek, Y. | 登録日 | 2018-04-11 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.114 Å) | 主引用文献 | Small-molecule inhibitor of HlyU attenuates virulence of Vibrio species. Sci Rep, 9, 2019
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7X01
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![BU of 7x01 by Molmil](/molmil-images/mine/7x01) | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with inhibitor FHA | 分子名称: | (1R,2S,3S,4R,5R)-3-(6-aminopurin-9-yl)-4-fluoranyl-5-(2-hydroxyethyl)cyclopentane-1,2-diol, ZINC ION, mRNA-capping enzyme nsP1 | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | 登録日 | 2022-02-20 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1. Cell Rep, 40, 2022
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7FGG
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![BU of 7fgg by Molmil](/molmil-images/mine/7fgg) | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GTP | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | 登録日 | 2021-07-27 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1. Cell Rep, 40, 2022
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7FGH
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![BU of 7fgh by Molmil](/molmil-images/mine/7fgh) | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GMP | 分子名称: | N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | 登録日 | 2021-07-27 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (2.18 Å) | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1. Cell Rep, 40, 2022
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7FGI
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![BU of 7fgi by Molmil](/molmil-images/mine/7fgi) | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU | 分子名称: | MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | 登録日 | 2021-07-27 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1. Cell Rep, 40, 2022
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