7YQ8
 
 | | Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide | | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... | | 著者 | Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. | | 登録日 | 2022-08-05 | | 公開日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes.
Nat Commun, 14, 2023
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7EWL
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7EWP
 | | Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:1:1 ratio | | 分子名称: | Guanine nucleotide-binding protein subunit beta-5, Probable G-protein coupled receptor 158, Regulator of G-protein signaling 7 | | 著者 | Kim, Y, Jeong, E, Jeong, J, Cho, Y. | | 登録日 | 2021-05-25 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure of the class C orphan GPCR GPR158 in complex with RGS7-G beta 5.
Nat Commun, 12, 2021
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7EWR
 | | Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:2:2 ratio | | 分子名称: | Guanine nucleotide-binding protein subunit beta-5, Probable G-protein coupled receptor 158, Regulator of G-protein signaling 7 | | 著者 | Kim, Y, Jeong, E, Jeong, J, Cho, Y. | | 登録日 | 2021-05-26 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structure of the class C orphan GPCR GPR158 in complex with RGS7-G beta 5.
Nat Commun, 12, 2021
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3ZPJ
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3ZG7
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3ZG8
 | | Crystal Structure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form | | 分子名称: | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, PENICILLIN-BINDING PROTEIN, ... | | 著者 | Jeong, J.H, Kim, Y.G. | | 登録日 | 2012-12-17 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.094 Å) | | 主引用文献 | Crystal Structures of Bifunctional Penicillin-Binding Protein 4 from Listeria Monocytogenes.
Antimicrob.Agents Chemother., 57, 2013
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3ZGA
 | | Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form | | 分子名称: | (2R,4S)-2-[(1R)-1-{[(2S)-2-carboxy-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, PENICILLIN-BINDING PROTEIN 4 | | 著者 | Jeong, J.H, Kim, Y.G. | | 登録日 | 2012-12-17 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | Crystal Structures of Bifunctional Penicillin-Binding Protein 4 from Listeria Monocytogenes.
Antimicrob.Agents Chemother., 57, 2013
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4UZ0
 | | Crystal Structure of apoptosis repressor with CARD (ARC) | | 分子名称: | GLYCEROL, NUCLEOLAR PROTEIN 3 | | 著者 | Kim, S.H, Jeong, J.H, Jang, T.H, Kim, Y.G, Park, H.H. | | 登録日 | 2014-09-04 | | 公開日 | 2015-07-01 | | 最終更新日 | 2017-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | | 主引用文献 | Crystal Structure of Caspase Recruiting Domain (Card) of Apoptosis Repressor with Card (Arc) and its Implication in Inhibition of Apoptosis.
Sci.Rep., 5, 2015
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4UOX
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4UOY
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4ENO
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8DF1
 | | Chi3l1 bound by antibody C59 | | 分子名称: | C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ... | | 著者 | Wrapp, D, McLellan, J.S. | | 登録日 | 2022-06-21 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Antib Ther, 6, 2023
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8IEC
 | | Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | | 著者 | Shin, J, Park, J, Cho, Y. | | 登録日 | 2023-02-15 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
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8IEQ
 | | Cryo-EM structure of G-protein free GPR156 | | 分子名称: | Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate | | 著者 | Shin, J, Park, J, Cho, Y. | | 登録日 | 2023-02-15 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
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8IEI
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8IEB
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8IEP
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8IED
 | | Cryo-EM structure of GPR156-miniGo-scFv16 complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | | 著者 | Shin, J, Park, J, Cho, Y. | | 登録日 | 2023-02-15 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
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7CA3
 | | Cryo-EM structure of human GABA(B) receptor bound to the positive allosteric modulator rac-BHFF | | 分子名称: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | | 登録日 | 2020-06-08 | | 公開日 | 2020-11-11 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural Basis for Activation of the Heterodimeric GABA B Receptor.
J.Mol.Biol., 432, 2020
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7CUM
 | | Cryo-EM structure of human GABA(B) receptor bound to the antagonist CGP54626 | | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | | 登録日 | 2020-08-23 | | 公開日 | 2020-11-11 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structural Basis for Activation of the Heterodimeric GABA B Receptor.
J.Mol.Biol., 432, 2020
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7CA5
 | | Cryo-EM structure of human GABA(B) receptor in apo state | | 分子名称: | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2 | | 著者 | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | | 登録日 | 2020-06-08 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Structural Basis for Activation of the Heterodimeric GABA B Receptor.
J.Mol.Biol., 432, 2020
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