4TVX
| Crystal structure of the E. coli CRISPR RNA-guided surveillance complex, Cascade | 分子名称: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | 著者 | Jackson, R.N, Golden, S.M, Carter, J, Wiedenheft, B. | 登録日 | 2014-06-28 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli. Science, 345, 2014
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6NJY
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5CD4
| The Type IE CRISPR Cascade complex from E. coli, with two assemblies in the asymmetric unit arranged back-to-back | 分子名称: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | 著者 | Jackson, R.N, Golden, S.M, Carter, J, Wiedenheft, B. | 登録日 | 2015-07-03 | 公開日 | 2015-08-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli. Nucleic Acids Res., 43, 2015
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8E2W
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8V44
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5UZ9
| Cryo EM structure of anti-CRISPRs, AcrF1 and AcrF2, bound to type I-F crRNA-guided CRISPR surveillance complex | 分子名称: | Anti-CRISPR protein 30, Anti-CRISPR protein Acr30-35, CRISPR RNA (60-MER), ... | 著者 | Chowdhury, S, Carter, J, Rollins, M.F, Jackson, R.N, Hoffmann, C, Nosaka, L, Bondy-Denomy, J, Maxwell, K.L, Davidson, A.R, Fischer, E.R, Lander, G.C, Wiedenheft, B. | 登録日 | 2017-02-25 | 公開日 | 2017-04-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex. Cell, 169, 2017
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4QU4
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8D49
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8D4A
| Cas12a2 quaternary complex | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Bravo, J.P.K, Taylor, D.W. | 登録日 | 2022-06-01 | 公開日 | 2023-01-18 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature, 613, 2023
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8D4B
| Structure of Cas12a2 ternary complex | 分子名称: | OrfB_Zn_ribbon domain-containing protein, RNA (28-MER), RNA (41-MER) | 著者 | Bravo, J.P.K, Taylor, D.W. | 登録日 | 2022-06-01 | 公開日 | 2023-01-18 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature, 613, 2023
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7JHY
| Type IV-B CRISPR Complex | 分子名称: | Csf2 (Cas7), Csf4 (Cas11), RNA (31-MER) | 著者 | Bravo, J.P.K, Taylor, D.W. | 登録日 | 2020-07-21 | 公開日 | 2021-03-31 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of a type IV CRISPR-Cas ribonucleoprotein complex. Iscience, 24, 2021
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