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3SOE
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BU of 3soe by Molmil
Crystal Structure of the 3rd PDZ domain of the human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (MAGI3)
分子名称: 1,2-ETHANEDIOL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
著者Ivarsson, Y, Filippakopoulos, P, Picaud, S, Vollmar, M, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Knapp, S, Zimmermann, P, Structural Genomics Consortium (SGC)
登録日2011-06-30
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the 3rd PDZ domain of the human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (MAGI3)
To be Published
7ZX4
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BU of 7zx4 by Molmil
Clathrin N-terminal domain in complex with a HURP phospho-peptide
分子名称: CHLORIDE ION, Clathrin heavy chain 1, Disks large-associated protein 5, ...
著者Kliche, J, Badgujar, D, Dobritzsch, D, Ivarsson, Y.
登録日2022-05-20
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Mol.Syst.Biol., 19, 2023
6R8I
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BU of 6r8i by Molmil
PP4R3A EVH1 domain bound to FxxP motif
分子名称: SER-LEU-PRO-PHE-THR-PHE-LYS-VAL-PRO-ALA-PRO-PRO-PRO-SER-LEU-PRO-PRO-SER, Serine/threonine-protein phosphatase 4 regulatory subunit 3A
著者Ueki, Y, Kruse, T, Weisser, M.B, Sundell, G.N, Yoo Larsen, M.S, Lopez Mendez, B, Jenkins, N.P, Garvanska, D.H, Cressey, L, Zhang, G, Davey, N, Montoya, G, Ivarsson, Y, Kettenbach, A, Nilsson, J.
登録日2019-04-02
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.517 Å)
主引用文献A Consensus Binding Motif for the PP4 Protein Phosphatase.
Mol.Cell, 76, 2019
2C4J
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BU of 2c4j by Molmil
Human glutathione-S-transferase M2-2 T210S mutant in complex with glutathione-styrene oxide conjugate
分子名称: GLUTATHIONE S-TRANSFERASE MU 2, L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE
著者Tars, K, Andersson, M, Ivarsson, Y, Olin, B, Mannervik, B.
登録日2005-10-20
公開日2005-10-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Alternative Mutations of a Positively Selected Residue Elicit Gain or Loss of Functionalities in Enzyme Evolution.
Proc.Natl.Acad.Sci.USA, 103, 2006
4Z33
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BU of 4z33 by Molmil
Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
分子名称: ACETATE ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ...
著者Egea-Jimenez, A.L, Gallardo, R, Garcia-Pino, A, Ivarsson, Y, Wawrzyniak, A.M, Kashyap, R, Loris, R, Schymkowitz, J, Rousseau, F, Zimmermann, P.
登録日2015-03-30
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
To Be Published
7A9B
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BU of 7a9b by Molmil
Crystal structure of Shank1 PDZ domain with ARAP3-derived peptide
分子名称: 1,2-ETHANEDIOL, SH3 and multiple ankyrin repeat domains protein 1,Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
著者Mariam McAuley, M, Ali, M, Ivarsson, Y, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC)
登録日2020-09-01
公開日2020-10-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Shank1 PDZ domain with ARAP3-derived peptide
to be published
7SOY
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BU of 7soy by Molmil
The structure of the PP2A-B56gamma1 holoenzyme-PME-1 complex
分子名称: Isoform Gamma-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Protein phosphatase methylesterase 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
著者Li, Y, Balakrishnan, V.K, Rowse, M, Novikova, I.V, Xing, Y.
登録日2021-11-01
公開日2022-08-31
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition.
Elife, 11, 2022
4UPG
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BU of 4upg by Molmil
X-ray structure of calcium-free human sorcin
分子名称: DI(HYDROXYETHYL)ETHER, SORCIN, SULFATE ION
著者Ilari, A, Fiorillo, A, Colotti, G.
登録日2014-06-16
公開日2014-06-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of Sorcin-Mediated Calcium-Dependent Signal Transduction.
Sci.Rep., 5, 2015
6Y9P
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BU of 6y9p by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with Harmonin a1 C-terminal PDZ binding motif peptide
分子名称: Harmonin a1, Whirlin
著者Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
登録日2020-03-10
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.169 Å)
主引用文献Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
6Y38
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BU of 6y38 by Molmil
Crystal structure of Whirlin PDZ3 in complex with Myosin 15a C-terminal PDZ binding motif peptide
分子名称: Chains: C,D, Whirlin
著者Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
登録日2020-02-17
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
4USL
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BU of 4usl by Molmil
The X-ray structure of calcium bound human sorcin
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, SORCIN, ...
著者Ilari, A, Fiorillo, A, Colotti, G.
登録日2014-07-10
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis of Sorcin-Mediated Calcium-Dependent Signal Transduction.
Sci.Rep., 5, 2015
6ESP
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BU of 6esp by Molmil
Proteome-wide analysis of phospho-regulated PDZ domain interactions
分子名称: Protein scribble homolog
著者Chi, N.C.
登録日2017-10-24
公開日2018-09-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Proteome-wide analysis of phospho-regulated PDZ domain interactions.
Mol. Syst. Biol., 14, 2018
6Y9N
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BU of 6y9n by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with Myosin 15a C-terminal PDZ binding motif peptide
分子名称: Unconventional myosin-XV, Whirlin
著者Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
登録日2020-03-10
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
6Y9O
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BU of 6y9o by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with CASK internal PDZ binding motif peptide
分子名称: Peripheral plasma membrane protein CASK, Whirlin
著者Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
登録日2020-03-10
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.632 Å)
主引用文献Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
6Y9Q
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BU of 6y9q by Molmil
Crystal structure of Whirlin PDZ3_C-ter in complex with Taperin internal PDZ binding motif peptide
分子名称: Taperin, Whirlin
著者Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N.
登録日2020-03-10
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.315 Å)
主引用文献Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.
J.Mol.Biol., 432, 2020
9ATN
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BU of 9atn by Molmil
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
分子名称: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
著者Zhang, Y, Zandian, M, Kutateladze, T.
登録日2024-02-27
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
8U2Y
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BU of 8u2y by Molmil
Solution structure of the PHD6 finger of MLL4 bound to TET3
分子名称: Histone-lysine N-methyltransferase 2D, Methylcytosine dioxygenase TET3, ZINC ION
著者Mohid, S.A, Zandian, M, Zhang, Y, Kutateladze, T.G.
登録日2023-09-06
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献MLL4 binds TET3.
Structure, 32, 2024
6AK2
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BU of 6ak2 by Molmil
Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018
分子名称: Syntenin-1, peptide inhibitor KSL-128018
著者Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T.
登録日2018-08-29
公開日2019-09-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.868 Å)
主引用文献A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
J.Med.Chem., 64, 2021
4Q2O
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BU of 4q2o by Molmil
PDLIM4 PDZ in Complex with a Phage-Derived Peptide
分子名称: PDZ and LIM domain protein 4
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4Q2Q
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ZO1 PDZ3 in Complex with a Phage-Derived Peptide
分子名称: Tight junction protein ZO-1
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4Q2P
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NHERF3 PDZ2 in Complex with a Phage-Derived Peptide
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4Q2N
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INADL PDZ3 in Complex with a Phage-Derived Peptide
分子名称: 1,2-ETHANEDIOL, InaD-like protein
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
8FE6
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BU of 8fe6 by Molmil
Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide and UDP-GlcNAc
分子名称: A motif peptide, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Xie, J, Jiang, J.
登録日2022-12-05
公開日2023-08-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase.
Nat.Chem.Biol., 19, 2023
8FE7
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Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (SMG9) and UDP-GlcNAc
分子名称: Nonsense-mediated mRNA decay factor SMG9, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Xie, J, Jiang, J.
登録日2022-12-05
公開日2023-08-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase.
Nat.Chem.Biol., 19, 2023
8FUF
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Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (ZNF831) and UDP-GlcNAc
分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, Zinc finger protein 831
著者Xie, J, Jiang, J.
登録日2023-01-17
公開日2023-08-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase.
Nat.Chem.Biol., 19, 2023

 

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