2KFX
 
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5CJQ
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5CJS
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4M5Z
 | | Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit | | 分子名称: | Fab 5J8 heavy chain, Fab 5J8 light chain, Hemagglutinin HA1 chain | | 著者 | Hong, M, Lee, P.S, Wilson, I.A. | | 登録日 | 2013-08-08 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site.
J.Virol., 87, 2013
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4M5Y
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4M4Y
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4NM4
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4NM8
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2O7C
 | | Crystal structure of L-methionine-lyase from Pseudomonas | | 分子名称: | Methionine gamma-lyase, SULFATE ION | | 著者 | Misaki, S, Takimoto, A, Takakura, T, Yoshioka, T, Yamashita, M, Tamura, T, Tanaka, H, Inagaki, K. | | 登録日 | 2006-12-10 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution
J.Biochem.(Tokyo), 141, 2007
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1PFF
 | | Crystal Structure of Homocysteine alpha-, gamma-lyase at 1.8 Angstroms | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, methionine gamma-lyase | | 著者 | Allen, T.W, Sridhar, V, Prasad, S.G, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S. | | 登録日 | 2003-05-26 | | 公開日 | 2004-08-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 |
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1PG8
 | | Crystal Structure of L-methionine alpha-, gamma-lyase | | 分子名称: | DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Allen, T.W, Sridhar, V, Prasad, G.S, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S. | | 登録日 | 2003-05-28 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 |
To Be Published
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6FYT
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6FYW
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6FYS
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6FYU
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6OAC
 | | PQR530 [(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine] bound to the PI3Ka catalytic subunit p110alpha | | 分子名称: | 4-(difluoromethyl)-5-{4-[(3S)-3-methylmorpholin-4-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}pyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Burke, J.E, McPhail, J.A. | | 登録日 | 2019-03-15 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase.
J.Med.Chem., 62, 2019
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6TZZ
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6TZY
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6CNW
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6CNV
 | | INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 Fab heavy chain, ... | | 著者 | Luo, J, Obmolova, G. | | 登録日 | 2018-03-09 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
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6CK8
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6DJL
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7KIQ
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7LPP
 | | Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 1 | | 分子名称: | 4-(hydroxymethyl)-1-[[2-(3-methoxyphenyl)-1,3-thiazol-5-yl]methyl]piperidin-4-ol, Cytoplasmic protein, GLYCEROL, ... | | 著者 | Pereira de Sa, N, Del Poeta, M, Airola, M.V. | | 登録日 | 2021-02-12 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
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7LPQ
 | | Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 9 | | 分子名称: | Cytoplasmic protein, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Pereira de Sa, N, Del Poeta, M, Airola, M.V. | | 登録日 | 2021-02-12 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
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