6KCS
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7YBD
| Crystal structure of sliding DNA clamp of Clostridioides difficile | 分子名称: | Beta sliding clamp, TRIETHYLENE GLYCOL | 著者 | Hishiki, A, Okazaki, S, Hara, K, Hashimoto, H. | 登録日 | 2022-06-29 | 公開日 | 2022-10-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Crystal structure of the sliding DNA clamp from the Gram-positive anaerobic bacterium Clostridioides difficile. J.Biochem., 173, 2022
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4XZF
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2ZVL
| Crystal structure of PCNA in complex with DNA polymerase kappa fragment | 分子名称: | DNA polymerase kappa, Proliferating cell nuclear antigen, SULFATE ION, ... | 著者 | Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M. | 登録日 | 2008-11-11 | 公開日 | 2009-02-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen J.Biol.Chem., 284, 2009
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2ZVM
| Crystal structure of PCNA in complex with DNA polymerase iota fragment | 分子名称: | DNA polymerase iota, Proliferating cell nuclear antigen | 著者 | Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M. | 登録日 | 2008-11-11 | 公開日 | 2009-02-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen J.Biol.Chem., 284, 2009
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2ZVK
| Crystal structure of PCNA in complex with DNA polymerase eta fragment | 分子名称: | DNA polymerase eta, Proliferating cell nuclear antigen | 著者 | Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M. | 登録日 | 2008-11-11 | 公開日 | 2009-02-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen J.Biol.Chem., 284, 2009
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7V5N
| Crystal structure of Fab fragment of bevacizumab bound to DNA aptamer | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*GP*TP*TP*GP*GP*TP*GP*GP*TP*AP*GP*TP*TP*AP*CP*GP*TP*TP*CP*GP*C)-3'), IMIDAZOLE, ... | 著者 | Hishiki, A, Tong, J, Todoroki, K, Hashimoto, H. | 登録日 | 2021-08-17 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection. Biosens.Bioelectron., 203, 2022
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3VKX
| Structure of PCNA | 分子名称: | 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... | 著者 | Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. | 登録日 | 2011-11-26 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
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3ALR
| Crystal structure of Nanos | 分子名称: | Nanos protein, ZINC ION | 著者 | Hashimoto, H, Hara, K, Hishiki, A, Kawaguchi, S, Shichijo, N, Nakamura, K, Unzai, S, Tamaru, Y, Shimizu, T, Sato, M. | 登録日 | 2010-08-06 | 公開日 | 2011-02-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of zinc-finger domain of Nanos and its functional implications Embo Rep., 11, 2010
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4XZG
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3B0T
| Human VDR ligand binding domain in complex with maxacalcitol | 分子名称: | (1S,3R,5Z,7E,14beta,17alpha,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol, SULFATE ION, Vitamin D3 receptor | 著者 | Hishiki, A, Hashimoto, H, Sato, M, Shimizu, T. | 登録日 | 2011-06-14 | 公開日 | 2011-08-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Human VDR ligand binding domain in complex with maxacalcitol To be Published
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8WU8
| Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-RHINO(88-99) complex | 分子名称: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ... | 著者 | Hara, K, Nagata, K, Iida, N, Hashimoto, H. | 登録日 | 2023-10-20 | 公開日 | 2024-02-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural basis for intra- and intermolecular interactions on RAD9 subunit of 9-1-1 checkpoint clamp implies functional 9-1-1 regulation by RHINO. J.Biol.Chem., 300, 2024
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8GNN
| Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex | 分子名称: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Cell cycle checkpoint protein RAD17, ... | 著者 | Hara, K, Nagata, K, Iida, N, Hashimoto, H. | 登録日 | 2022-08-24 | 公開日 | 2023-03-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.119 Å) | 主引用文献 | The 9-1-1 DNA clamp subunit RAD1 forms specific interactions with clamp loader RAD17, revealing functional implications for binding-protein RHINO. J.Biol.Chem., 299, 2023
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3WGW
| Structure of PCNA bound to a small molecule inhibitor | 分子名称: | 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION | 著者 | Hashimoto, H. | 登録日 | 2013-08-12 | 公開日 | 2014-02-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
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6J8Y
| Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex | 分子名称: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ... | 著者 | Hara, K, Iida, N, Sakurai, H, Hashimoto, H. | 登録日 | 2019-01-21 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp. J.Biol.Chem., 295, 2020
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5YD8
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5XPU
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5XPT
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3W08
| Crystal structure of aldoxime dehydratase | 分子名称: | Aldoxime dehydratase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hashimoto, H, Nomura, J, Hashimoto, Y, Oinuma, K.I, Wada, K, Hishiki, A, Hara, K, Kobayashi, M. | 登録日 | 2012-10-24 | 公開日 | 2013-02-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of aldoxime dehydratase and its catalytic mechanism involved in carbon-nitrogen triple-bond synthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
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