1HTJ
| STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF | 分子名称: | KIAA0380 | 著者 | Longenecker, K.L, Lewis, M.E, Chikumi, H, Gutkind, J.S, Derewenda, Z.S. | 登録日 | 2000-12-29 | 公開日 | 2001-07-11 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases. Structure, 9, 2001
|
|
4N7F
| |
4N7H
| Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3 | 分子名称: | Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE | 著者 | Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J. | 登録日 | 2013-10-15 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J.Biol.Chem., 289, 2014
|
|
7SJ4
| Human Trio residues 1284-1959 in complex with Rac1 | 分子名称: | Ras-related C3 botulinum toxin substrate 1, Triple functional domain protein | 著者 | Chen, C.-L, Ravala, S.K, Bandekar, S.J, Cash, J, Tesmer, J.J.G. | 登録日 | 2021-10-15 | 公開日 | 2022-07-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1. J.Biol.Chem., 298, 2022
|
|
8TUA
| Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4) | 分子名称: | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | 著者 | Cash, J.N, Tesmer, J.J.G. | 登録日 | 2023-08-15 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4) Elife, 2024
|
|
6PCV
| Single Particle Reconstruction of Phosphatidylinositol (3,4,5) trisphosphate-dependent Rac exchanger 1 bound to G protein beta gamma subunits | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Phosphatidylinositol (3,4,5) trisphosphate-dependent Rac exchanger 1 | 著者 | Cash, J.N, Cianfrocco, M.A, Tesmer, J.J.G. | 登録日 | 2019-06-18 | 公開日 | 2019-10-23 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-electron microscopy structure and analysis of the P-Rex1-G beta gamma signaling scaffold. Sci Adv, 5, 2019
|
|
6D8Z
| |
4R7X
| |
4R7V
| |
1BAK
| |