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1HTJ
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BU of 1htj by Molmil
STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF
分子名称: KIAA0380
著者Longenecker, K.L, Lewis, M.E, Chikumi, H, Gutkind, J.S, Derewenda, Z.S.
登録日2000-12-29
公開日2001-07-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases.
Structure, 9, 2001
4N7F
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BU of 4n7f by Molmil
Crystal structure of 3rd WW domain of human Nedd4-1
分子名称: E3 ubiquitin-protein ligase NEDD4
著者Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日2013-10-15
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.102 Å)
主引用文献Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
4N7H
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Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3
分子名称: Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE
著者Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日2013-10-15
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
7SJ4
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BU of 7sj4 by Molmil
Human Trio residues 1284-1959 in complex with Rac1
分子名称: Ras-related C3 botulinum toxin substrate 1, Triple functional domain protein
著者Chen, C.-L, Ravala, S.K, Bandekar, S.J, Cash, J, Tesmer, J.J.G.
登録日2021-10-15
公開日2022-07-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1.
J.Biol.Chem., 298, 2022
8TUA
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BU of 8tua by Molmil
Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4)
分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
著者Cash, J.N, Tesmer, J.J.G.
登録日2023-08-15
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Full-length P-Rex1 in complex with inositol 1,3,4,5-tetrakisphosphate (IP4)
Elife, 2024
6PCV
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Single Particle Reconstruction of Phosphatidylinositol (3,4,5) trisphosphate-dependent Rac exchanger 1 bound to G protein beta gamma subunits
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Phosphatidylinositol (3,4,5) trisphosphate-dependent Rac exchanger 1
著者Cash, J.N, Cianfrocco, M.A, Tesmer, J.J.G.
登録日2019-06-18
公開日2019-10-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-electron microscopy structure and analysis of the P-Rex1-G beta gamma signaling scaffold.
Sci Adv, 5, 2019
6D8Z
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Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio
分子名称: Triple functional domain protein
著者Bandekar, S, Tesmer, J.J.
登録日2018-04-27
公開日2019-02-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
Sci Signal, 12, 2019
4R7X
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Crystal structure of N-lobe of human ARRDC3(1-180)
分子名称: Arrestin domain-containing protein 3, PHOSPHATE ION
著者Qi, S, Hurley, J.
登録日2014-08-28
公開日2014-10-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Insights into beta 2-adrenergic receptor binding from structures of the N-terminal lobe of ARRDC3.
Protein Sci., 23, 2014
4R7V
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Crystal structure of N-lobe of human ARRDC3(1-165)
分子名称: Arrestin domain-containing protein 3
著者Qi, S, Hurley, J.
登録日2014-08-28
公開日2014-10-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Insights into beta 2-adrenergic receptor binding from structures of the N-terminal lobe of ARRDC3.
Protein Sci., 23, 2014
1BAK
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BU of 1bak by Molmil
SIGNAL TRANSDUCTION PLECKSTRIN HOMOLOGY DOMAIN OF G-PROTEIN COUPLED RECEPTOR KINASE 2 (BETA-ADRENERGIC RECEPTOR KINASE 1), C-TERMINAL EXTENDED, NMR, 20 STRUCTURES
分子名称: G-PROTEIN COUPLED RECEPTOR KINASE 2
著者Fushman, D, Cowburn, D.
登録日1997-11-21
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunits.
J.Biol.Chem., 273, 1998

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件を2024-10-30に公開中

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