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5DHH
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BU of 5dhh by Molmil
The crystal structure of nociceptin/orphanin FQ peptide receptor (NOP) in complex with SB-612111 (PSI Community Target)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (5S,7S)-7-{[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl}-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol, OLEIC ACID, ...
著者Miller, R.L, Thompson, A.A, Trapella, C, Guerrini, R, Malfacini, D, Patel, N, Han, G.W, Cherezov, V, Calo, G, Katritch, V, Stevens, R.C, GPCR Network (GPCR)
登録日2015-08-31
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor.
Structure, 23, 2015
5DHG
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BU of 5dhg by Molmil
The crystal structure of nociceptin/orphanin FQ peptide receptor (NOP) in complex with C-35 (PSI Community Target)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-benzyl-N-{3-[4-(2,6-dichlorophenyl)piperidin-1-yl]propyl}-D-prolinamide, OLEIC ACID, ...
著者Miller, R.L, Thompson, A.A, Trapella, C, Guerrini, R, Malfacini, D, Patel, N, Han, G.W, Cherezov, V, Calo, G, Katritch, V, Stevens, R.C, GPCR Network (GPCR)
登録日2015-08-30
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor.
Structure, 23, 2015
1IYT
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BU of 1iyt by Molmil
Solution structure of the Alzheimer's disease amyloid beta-peptide (1-42)
分子名称: Alzheimer's disease amyloid
著者Crescenzi, O, Tomaselli, S, Guerrini, R, Salvadori, S, D'Ursi, A.M, Temussi, P.A, Picone, D.
登録日2002-09-06
公開日2003-02-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain.
EUR.J.BIOCHEM., 269, 2002
1Z0Q
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BU of 1z0q by Molmil
Aqueous Solution Structure of the Alzheimer's Disease Abeta Peptide (1-42)
分子名称: Alzheimer's disease amyloid
著者Tomaselli, S, Esposito, V, Vangone, P, van Nuland, N.A, Bonvin, A.M, Guerrini, R, Tancredi, T, Temussi, P.A, Picone, D.
登録日2005-03-02
公開日2006-05-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The alpha-to-beta Conformational Transition of Alzheimer's Abeta-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of beta Conformation Seeding
Chembiochem, 7, 2006
1RGW
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BU of 1rgw by Molmil
Solution Structure of ZASP's PDZ domain
分子名称: ZASP protein
著者Au, Y, Atkinson, R.A, Pallavicini, A, Joseph, C, Martin, S.R, Muskett, F.W, Guerrini, R, Faulkner, G, Pastore, A.
登録日2003-11-13
公開日2004-04-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of ZASP PDZ Domain; Implications for Sarcomere Ultrastructure and Enigma Family Redundancy.
Structure, 12, 2004
4EA3
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BU of 4ea3 by Molmil
Structure of the N/OFQ Opioid Receptor in Complex with a Peptide Mimetic
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-benzyl-N-[3-(1'H,3H-spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]-D-prolinamide, ...
著者Thompson, A.A, Liu, W, Chun, E, Katritch, V, Wu, H, Vardy, E, Huang, X.P, Trapella, C, Guerrini, R, Calo, G, Roth, B.L, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
登録日2012-03-22
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.013 Å)
主引用文献Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.
Nature, 485, 2012
1QXC
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BU of 1qxc by Molmil
NMR structure of the fragment 25-35 of beta amyloid peptide in 20/80 v:v hexafluoroisopropanol/water mixture
分子名称: 11-mer peptide from Amyloid beta A4 protein
著者D'Ursi, A.M, Armenante, M.R, Guerrini, R, Salvadori, S, Sorrentino, G, Picone, D.
登録日2003-09-05
公開日2004-09-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of amyloid beta-peptide (25-35) in different media
J.Med.Chem., 47, 2004
1QWP
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BU of 1qwp by Molmil
NMR analysis of 25-35 fragment of beta amyloid peptide
分子名称: 11-mer peptide from Amyloid beta A4 protein
著者D'Ursi, A.M, Armenante, M.R, Guerrini, R, Salvadori, S, Sorrentino, G, Picone, D.
登録日2003-09-03
公開日2004-09-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of amyloid beta-peptide (25-35) in different media
J.Med.Chem., 47, 2004
1QYT
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BU of 1qyt by Molmil
Solution structure of fragment (25-35) of beta amyloid peptide in SDS micellar solution
分子名称: 11-mer peptide from Amyloid beta A4 protein
著者D'Ursi, A.M, Armenante, M.R, Guerrini, R, Salvadori, S, Sorrentino, G, Picone, D.
登録日2003-09-12
公開日2004-12-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of amyloid beta-peptide (25-35) in different media
J.Med.Chem., 47, 2004
4O1U
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BU of 4o1u by Molmil
Crystal structure of human thymidylate synthase mutant Y202C
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
著者Pozzi, C, Mangani, S.
登録日2013-12-16
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Elife, 11, 2022
4O1X
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BU of 4o1x by Molmil
Crystal structure of human thymidylate synthase double mutant C195S-Y202C
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
著者Pozzi, C, Mangani, S.
登録日2013-12-16
公開日2015-01-21
最終更新日2023-03-01
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Elife, 11, 2022
6R82
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BU of 6r82 by Molmil
Crystal structure of the TLDc domain of Skywalker/TBC1D24 from Drosophila melanogaster
分子名称: GTPase-activating protein skywalker
著者Fischer, B, Paesmans, J, Versees, W.
登録日2019-03-30
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.046 Å)
主引用文献TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model.
Brain, 142, 2019
2BTT
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BU of 2btt by Molmil
NMR Structure of MYO3-SH3 domain from Myosin-typeI from S. cerevisiae
分子名称: MYOSIN-3 ISOFORM
著者Musi, V, Birdsall, B, Pastore, A.
登録日2005-06-06
公開日2006-04-12
最終更新日2024-04-24
実験手法SOLUTION NMR
主引用文献New approaches to high-throughput structure characterization of SH3 complexes: the example of Myosin-3 and Myosin-5 SH3 domains from S. cerevisiae.
Protein Sci., 15, 2006
3N5G
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BU of 3n5g by Molmil
Crystal Structure of histidine-tagged human thymidylate synthase
分子名称: SULFATE ION, Thymidylate synthase
著者Pozzi, C, Cardinale, D, Guaitoli, G, Tondi, D, Luciani, R, Myllykallio, H, Ferrari, S, Costi, M.P, Mangani, S.
登録日2010-05-25
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3N5E
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BU of 3n5e by Molmil
Crystal Structure of human thymidylate synthase bound to a peptide inhibitor
分子名称: SULFATE ION, Synthetic peptide LR, Thymidylate synthase
著者Pozzi, C, Cardinale, D, Guaitoli, G, Tondi, D, Luciani, R, Myllykallio, H, Ferrari, S, Costi, M.P, Mangani, S.
登録日2010-05-25
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011

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