7SJN
 
 | | HtrA1:Fab15H6.v4 complex | | 分子名称: | Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1 | | 著者 | Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D. | | 登録日 | 2021-10-18 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
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7SJO
 | | HtrA1S328A:Fab15H6.v4 complex | | 分子名称: | Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1 | | 著者 | Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D. | | 登録日 | 2021-10-18 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
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7SJM
 | | anti-HtrA1 Fab15H6.v4 | | 分子名称: | GLYCEROL, Heavy Chain, Light Chain, ... | | 著者 | Ultsch, M.H, Gerhardy, S. | | 登録日 | 2021-10-18 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
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7SJP
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6FAI
 | | Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit | | 分子名称: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Scaiola, A, Pena, C, Weisser, M, Boehringer, D, Leibundgut, M, Klingauf-Nerurkar, P, Gerhardy, S, Panse, V.G, Ban, N. | | 登録日 | 2017-12-15 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit.
EMBO J., 37, 2018
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5APO
 | | Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1 | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N. | | 登録日 | 2015-09-17 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
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5APN
 | | Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1 | | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V. | | 登録日 | 2015-09-17 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell, 164, 2015
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7QDD
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6MV5
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2MJH
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7QDE
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6E4Y
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6E4Z
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7LFA
 | | Fab 3B6 bound to ApoL1 NTD | | 分子名称: | Apolipoprotein L1, CHLORIDE ION, Fab 3B6 heavy chain, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-15 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.857 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
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7L6K
 | | ApoL1 N-terminal domain | | 分子名称: | Apolipoprotein L1 | | 著者 | Holliday, M.J, Ultsch, M, Moran, P, Fairbrother, W.J, Kirchhofer, D. | | 登録日 | 2020-12-23 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
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7LFB
 | | Fab 7D6 bound to ApoL1 NTD | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Apolipoprotein L1, Fab 7D6 heavy chain, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.913 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
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7LF7
 | | Fab 6D12 bound to ApoL1 NTD | | 分子名称: | Apolipoprotein L1, ETHANOL, Fab 6D12 heavy chain, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-15 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.026 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
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7LF8
 | | Fab 6D12 bound to ApoL2 NTD | | 分子名称: | Apolipoprotein L2, Fab 6D12 heavy chain, Fab 6D12 light chain, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-15 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
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7LFD
 | | Fab 7D6 bound to ApoL1 BH3 like peptide | | 分子名称: | AMMONIUM ION, Apolipoprotein L1 BH3 like peptide, CITRATE ANION, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.157 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
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