1XSL
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![BU of 1xsl by Molmil](/molmil-images/mine/1xsl) | Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap | 分子名称: | 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*CP*CP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Kunkel, T.A, Pedersen, L.C. | 登録日 | 2004-10-19 | 公開日 | 2005-01-18 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A closed conformation for the Pol lambda catalytic cycle. Nat.Struct.Mol.Biol., 12, 2005
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1XSP
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![BU of 1xsp by Molmil](/molmil-images/mine/1xsp) | Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate | 分子名称: | 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Kunkel, T.A, Pedersen, L.C. | 登録日 | 2004-10-19 | 公開日 | 2005-01-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A closed conformation for the Pol lambda catalytic cycle. Nat.Struct.Mol.Biol., 12, 2005
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1XSN
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![BU of 1xsn by Molmil](/molmil-images/mine/1xsn) | Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap and ddTTP | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*(2DT))-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Kunkel, T.A, Pedersen, L.C. | 登録日 | 2004-10-19 | 公開日 | 2005-01-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A closed conformation for the Pol lambda catalytic cycle. Nat.Struct.Mol.Biol., 12, 2005
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3HX0
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![BU of 3hx0 by Molmil](/molmil-images/mine/3hx0) | ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*T)-3', 5'-D(*CP*GP*GP*CP*AP*AP*AP*TP*AP*CP*TP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Larrea, A.A, Havener, J.M, Perera, L, Krahn, J.M, Pedersen, L.C, Ramsden, D.A, Kunkel, T.A. | 登録日 | 2009-06-19 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Scrunching During DNA Repair Synthesis To be Published
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3HW8
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![BU of 3hw8 by Molmil](/molmil-images/mine/3hw8) | ternary complex of DNA polymerase lambda of a two nucleotide gapped DNA substrate with a C in the scrunch site | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*T)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Larrea, A.A, Havener, J.M, Perera, L, Krahn, J.M, Pedersen, L.C, Ramsden, D.A, Kunkel, T.A. | 登録日 | 2009-06-17 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Scrunching Durning DNA Repair Synthesis To be Published
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3HWT
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![BU of 3hwt by Molmil](/molmil-images/mine/3hwt) | Ternary complex of DNA polymerase lambda bound to a two nucleotide gapped DNA substrate with a scrunched dA | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*(2DT))-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Larrea, A.A, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2009-06-18 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Scrunching during DNA repair synthesis To be Published
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2PFP
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![BU of 2pfp by Molmil](/molmil-images/mine/2pfp) | DNA Polymerase lambda in complex with DNA and dCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2007-04-05 | 公開日 | 2007-05-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
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2PFN
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![BU of 2pfn by Molmil](/molmil-images/mine/2pfn) | Na in the active site of DNA Polymerase lambda | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2007-04-05 | 公開日 | 2007-05-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
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2PFQ
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![BU of 2pfq by Molmil](/molmil-images/mine/2pfq) | Manganese promotes catalysis in a DNA polymerase lambda-DNA crystal | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2007-04-05 | 公開日 | 2007-05-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
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2PFO
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![BU of 2pfo by Molmil](/molmil-images/mine/2pfo) | DNA Polymerase lambda in complex with DNA and dUPNPP | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2007-04-05 | 公開日 | 2007-05-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
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3MDA
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![BU of 3mda by Molmil](/molmil-images/mine/3mda) | DNA polymerase lambda in complex with araC | 分子名称: | DNA (5'-D(*CP*AP*GP*TP*AP*CP*(CAR))-3'), DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ... | 著者 | Garcia-Diaz, M, Murray, M, Kunkel, T, Chou, K.M. | 登録日 | 2010-03-30 | 公開日 | 2010-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | 主引用文献 | Interaction between DNA Polymerase lambda and anticancer nucleoside analogs. J.Biol.Chem., 285, 2010
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3MDC
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![BU of 3mdc by Molmil](/molmil-images/mine/3mdc) | DNA polymerase lambda in complex with dFdCTP | 分子名称: | 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3'), ... | 著者 | Garcia-Diaz, M, Murray, M, Kunkel, T, Chou, K.M. | 登録日 | 2010-03-30 | 公開日 | 2010-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Interaction between DNA Polymerase lambda and anticancer nucleoside analogs. J.Biol.Chem., 285, 2010
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2BCU
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![BU of 2bcu by Molmil](/molmil-images/mine/2bcu) | DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp and a T:T mismatch | 分子名称: | 5'-D(*CP*AP*GP*TP*TP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*AP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2005-10-19 | 公開日 | 2006-03-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124, 2006
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2BCV
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![BU of 2bcv by Molmil](/molmil-images/mine/2bcv) | DNA polymerase lambda in complex with Dttp and a DNA duplex containing an unpaired Dtmp | 分子名称: | 5'-D(*CP*AP*GP*TP*AP*(O2C))-3', 5'-D(*CP*GP*GP*CP*AP*GP*TP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2005-10-19 | 公開日 | 2006-03-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124, 2006
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2BCS
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![BU of 2bcs by Molmil](/molmil-images/mine/2bcs) | DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dcmp | 分子名称: | 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*CP*TP*AP*CP*TP*G)-3', 5'-D(*GP*CP*CP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2005-10-19 | 公開日 | 2006-03-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124, 2006
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2BCR
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![BU of 2bcr by Molmil](/molmil-images/mine/2bcr) | DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*AP*TP*AP*CP*TP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2005-10-19 | 公開日 | 2006-03-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124, 2006
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2BCQ
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![BU of 2bcq by Molmil](/molmil-images/mine/2bcq) | DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dtmp | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*TP*TP*AP*CP*TP*G)-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2005-10-19 | 公開日 | 2006-03-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase Cell(Cambridge,Mass.), 124, 2006
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1RZT
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![BU of 1rzt by Molmil](/molmil-images/mine/1rzt) | Crystal structure of DNA polymerase lambda complexed with a two nucleotide gap DNA molecule | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*AP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*G)-3', ... | 著者 | Pedersen, L.C, Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Blanco, L, Kunkel, T.A. | 登録日 | 2003-12-29 | 公開日 | 2004-03-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Mol.Cell, 13, 2004
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2GWS
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![BU of 2gws by Molmil](/molmil-images/mine/2gws) | Crystal Structure of human DNA Polymerase lambda with a G/G mismatch in the primer terminus | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*G)-3', ... | 著者 | Garcia-Diaz, M, Picher, A.J, Bebenek, K, Pedersen, L.C, Kunkel, T.A, Blanco, L. | 登録日 | 2006-05-05 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Promiscuous mismatch extension by human DNA polymerase lambda. Nucleic Acids Res., 34, 2006
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3C5G
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![BU of 3c5g by Molmil](/molmil-images/mine/3c5g) | Structure of a ternary complex of the R517K Pol lambda mutant | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*(2DT))-3'), ... | 著者 | Garcia-Diaz, M, Bebenek, K, Foley, M.C, Pedersen, L.C, Schlick, T, Kunkel, T.A. | 登録日 | 2008-01-31 | 公開日 | 2008-07-29 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Embo Rep., 9, 2008
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3C5F
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![BU of 3c5f by Molmil](/molmil-images/mine/3c5f) | Structure of a binary complex of the R517A Pol lambda mutant | 分子名称: | DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*DC)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DCP*DGP*DTP*DAP*DCP*DTP*DG)-3'), DNA (5'-D(P*DGP*DCP*DCP*DG)-3'), ... | 著者 | Garcia-Diaz, M, Bebenek, K, Foley, M.C, Pedersen, L.C, Schlick, T, Kunkel, T.A. | 登録日 | 2008-01-31 | 公開日 | 2008-09-02 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Embo Rep., 9, 2008
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3MGI
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![BU of 3mgi by Molmil](/molmil-images/mine/3mgi) | Ternary complex of a DNA polymerase lambda loop mutant | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA, DNA (5'-D(*CP*AP*GP*TP*AP*T)-3'), ... | 著者 | Garcia-Diaz, M, Bebenek, K, Zhou, R.Z, Povirk, L.F, Kunkel, T. | 登録日 | 2010-04-06 | 公開日 | 2010-05-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | 主引用文献 | Loop 1 modulates the fidelity of DNA polymerase lambda Nucleic Acids Res., 38, 2010
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3MGH
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![BU of 3mgh by Molmil](/molmil-images/mine/3mgh) | Binary complex of a DNA polymerase lambda loop mutant | 分子名称: | DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ... | 著者 | Garcia-Diaz, M, Bebenek, K, Zhou, R.Z, Povirk, L.F, Kunkel, T. | 登録日 | 2010-04-06 | 公開日 | 2010-05-19 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Loop 1 modulates the fidelity of DNA polymerase lambda Nucleic Acids Res., 38, 2010
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4W78
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![BU of 4w78 by Molmil](/molmil-images/mine/4w78) | Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis | 分子名称: | CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... | 著者 | Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M. | 登録日 | 2014-08-21 | 公開日 | 2014-10-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.541 Å) | 主引用文献 | A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis. Acs Chem.Biol., 9, 2014
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4WNB
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![BU of 4wnb by Molmil](/molmil-images/mine/4wnb) | Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis bound to 3-OPC-CoA | 分子名称: | 3-oxo-4-pregnene-20-carboxyl-Coenzyme A, CADMIUM ION, CALCIUM ION, ... | 著者 | Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M. | 登録日 | 2014-10-11 | 公開日 | 2014-10-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis. Acs Chem.Biol., 9, 2014
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