1XSP

Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate

Summary for 1XSP

• Entry DOI: 10.2210/pdb1xsp/pdb
• Related: 1XSL 1XSN
• Descriptor: 5'-D(*CP*GP*GP*CP*CP*GP*TP*AP*CP*TP*G)-3', 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... (7 entities in total)
• Functional Keywords: dna polymerase lambda, protein-dna complex, helix-hairpin-helix, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q9UGP5
• Total number of polymer chains: 4
• Total formula weight: 44382.05

Authors

Garcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Kunkel, T.A.,Pedersen, L.C. (deposition date: 2004-10-19, release date: 2005-01-18, Last modification date: 2024-02-14)

• Primary citation: Garcia-Diaz, M.,Bebenek, K.,Krahn, J.M.,Kunkel, T.A.,Pedersen, L.C.; A closed conformation for the Pol lambda catalytic cycle.; Nat.Struct.Mol.Biol., 12:97-98, 2005; PubMed: 15608652; DOI: 10.1038/nsmb876

Experimental method

X-RAY DIFFRACTION (2.2 Å)