5WRV
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![BU of 5wrv by Molmil](/molmil-images/mine/5wrv) | Complex structure of human SRP72/SRP68 | 分子名称: | ACETATE ION, GLYCEROL, SODIUM ION, ... | 著者 | Gao, Y, Chen, Z. | 登録日 | 2016-12-04 | 公開日 | 2017-06-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation J Mol Cell Biol, 9, 2017
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8QQK
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![BU of 8qqk by Molmil](/molmil-images/mine/8qqk) | Cryo-EM structure of E. coli cytochrome bo3 quinol oxidase assembled in peptidiscs | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, ... | 著者 | Gao, Y, Zhang, Y, Hakke, S, Peters, P.J, Ravelli, R.B.G. | 登録日 | 2023-10-05 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of cytochrome bo 3 quinol oxidase assembled in peptidiscs reveals an "open" conformation for potential ubiquinone-8 release. Biochim Biophys Acta Bioenerg, 1865, 2024
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6PZQ
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6OYA
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![BU of 6oya by Molmil](/molmil-images/mine/6oya) | Structure of the Rhodopsin-Transducin-Nanobody Complex | 分子名称: | Camelid antibody VHH fragment, Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | 登録日 | 2019-05-14 | 公開日 | 2019-07-24 | 最終更新日 | 2019-12-04 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Mol.Cell, 75, 2019
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6OY9
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![BU of 6oy9 by Molmil](/molmil-images/mine/6oy9) | Structure of the Rhodopsin-Transducin Complex | 分子名称: | Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | 著者 | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | 登録日 | 2019-05-14 | 公開日 | 2019-07-24 | 最終更新日 | 2019-12-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Mol.Cell, 75, 2019
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1CL4
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7JSN
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![BU of 7jsn by Molmil](/molmil-images/mine/7jsn) | Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6 | 分子名称: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, GUANOSINE-3',5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Gao, Y, Eskici, G, Ramachandran, S, Skiniotis, G, Cerione, R.A. | 登録日 | 2020-08-15 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6. Mol.Cell, 80, 2020
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7M3G
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![BU of 7m3g by Molmil](/molmil-images/mine/7m3g) | Asymmetric Activation of the Calcium Sensing Receptor Homodimer | 分子名称: | 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | 登録日 | 2021-03-18 | 公開日 | 2021-06-30 | 最終更新日 | 2021-07-21 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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7M3J
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![BU of 7m3j by Molmil](/molmil-images/mine/7m3j) | Asymmetric Activation of the Calcium Sensing Receptor Homodimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ... | 著者 | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | 登録日 | 2021-03-18 | 公開日 | 2021-06-30 | 最終更新日 | 2021-07-21 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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7M3E
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![BU of 7m3e by Molmil](/molmil-images/mine/7m3e) | Asymmetric Activation of the Calcium Sensing Receptor Homodimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ... | 著者 | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | 登録日 | 2021-03-18 | 公開日 | 2021-06-30 | 最終更新日 | 2021-07-21 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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7M3F
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![BU of 7m3f by Molmil](/molmil-images/mine/7m3f) | Asymmetric Activation of the Calcium Sensing Receptor Homodimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Gao, Y, Robertson, M.J, Zhang, C, Meyerowitz, J.G, Panova, O, Skiniotis, G. | 登録日 | 2021-03-18 | 公開日 | 2021-06-30 | 最終更新日 | 2021-07-21 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Asymmetric activation of the calcium-sensing receptor homodimer. Nature, 595, 2021
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7BST
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![BU of 7bst by Molmil](/molmil-images/mine/7bst) | EcoR124I-Ocr in the Intermediate State | 分子名称: | Overcome classical restriction gp0.3, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | 著者 | Gao, Y, Gao, P. | 登録日 | 2020-03-31 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.37 Å) | 主引用文献 | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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7BTR
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![BU of 7btr by Molmil](/molmil-images/mine/7btr) | EcoR124I-ArdA in the Restriction-Alleviation State | 分子名称: | Antirestriction protein ArdA, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | 著者 | Gao, Y, Gao, P. | 登録日 | 2020-04-02 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.54 Å) | 主引用文献 | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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7BTO
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![BU of 7bto by Molmil](/molmil-images/mine/7bto) | EcoR124I-ArdA in the Translocation State | 分子名称: | Antirestriction protein ArdA, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | 著者 | Gao, Y, Gao, P. | 登録日 | 2020-04-02 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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7BTQ
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![BU of 7btq by Molmil](/molmil-images/mine/7btq) | EcoR124I-DNA in the Restriction-Alleviation State | 分子名称: | DNA (64-MER), Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | 著者 | Gao, Y, Gao, P. | 登録日 | 2020-04-02 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.54 Å) | 主引用文献 | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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7BTP
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![BU of 7btp by Molmil](/molmil-images/mine/7btp) | EcoR124I-Ocr in Restriction-Alleviation State | 分子名称: | Overcome classical restriction gp0.3, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | 著者 | Gao, Y, Gao, P. | 登録日 | 2020-04-02 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.01 Å) | 主引用文献 | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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2DU9
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![BU of 2du9 by Molmil](/molmil-images/mine/2du9) | crystal structure of the transcriptional factor from C.glutamicum | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Predicted transcriptional regulators | 著者 | Gao, Y, Yao, M, Tanaka, I. | 登録日 | 2006-07-20 | 公開日 | 2007-07-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | The structures of transcription factor CGL2947 from Corynebacterium glutamicum in two crystal forms: A novel homodimer assembling and the implication for effector-binding mode Protein Sci., 16, 2007
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7BTF
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![BU of 7btf by Molmil](/molmil-images/mine/7btf) | SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-04-01 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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5IS0
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![BU of 5is0 by Molmil](/molmil-images/mine/5is0) | Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc | 分子名称: | Transient receptor potential cation channel subfamily V member 1, capsazepine | 著者 | Gao, Y, Cao, E, Julius, D, Cheng, Y. | 登録日 | 2016-03-15 | 公開日 | 2016-05-25 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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5IRX
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![BU of 5irx by Molmil](/molmil-images/mine/5irx) | Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc | 分子名称: | (2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | 著者 | Gao, Y, Cao, E, Julius, D, Cheng, Y. | 登録日 | 2016-03-14 | 公開日 | 2016-05-25 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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5IRZ
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![BU of 5irz by Molmil](/molmil-images/mine/5irz) | Structure of TRPV1 determined in lipid nanodisc | 分子名称: | (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(pentanoyloxy)propan-2-yl decanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | 著者 | Gao, Y, Cao, E, Julius, D, Cheng, Y. | 登録日 | 2016-03-15 | 公開日 | 2016-05-25 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534, 2016
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3UBU
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![BU of 3ubu by Molmil](/molmil-images/mine/3ubu) | Crystal structure of agkisacucetin, a GpIb-binding snaclec (snake C-type lectin) that inhibits platelet | 分子名称: | Agglucetin subunit alpha-1, Agglucetin subunit beta-2, GLYCEROL, ... | 著者 | Gao, Y, Ge, H, Chen, H, Li, H, Liu, Y, Niu, L, Teng, M. | 登録日 | 2011-10-25 | 公開日 | 2012-04-11 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Crystal structure of agkisacucetin, a Gpib-binding snake C-type lectin that inhibits platelet adhesion and aggregation. Proteins, 2012
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5KFC
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5KFL
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5KFX
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