1W4R
 
 | | Structure of a type II thymidine kinase with bound dTTP | | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Birringer, M.S, Claus, M.T, Folkers, G, Kloer, D.P, Schulz, G.E, Scapozza, L. | | 登録日 | 2004-07-27 | | 公開日 | 2005-02-01 | | 最終更新日 | 2013-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structure of a Type II Thymidine Kinase with Bound Dttp
FEBS Lett., 579, 2005
|
|
1Z6B
 | | Crystal structure of Plasmodium falciparum FabZ at 2.1 A | | 分子名称: | CACODYLATE ION, CHLORIDE ION, SULFATE ION, ... | | 著者 | Kostrewa, D, Winkler, F.K, Folkers, G, Scapozza, L, Perozzo, R. | | 登録日 | 2005-03-22 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum
PROTEIN SCI., 14, 2005
|
|
1Z00
 | | Solution structure of the C-terminal domain of ERCC1 complexed with the C-terminal domain of XPF | | 分子名称: | DNA excision repair protein ERCC-1, DNA repair endonuclease XPF | | 著者 | Tripsianes, K, Folkers, G, Ab, E, Das, D, Odijk, H, Jaspers, N.G.J, Hoeijmakers, J.H.J, Kaptein, R, Boelens, R. | | 登録日 | 2005-03-01 | | 公開日 | 2005-12-20 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure of the Human ERCC1/XPF Interaction Domains Reveals a Complementary Role for the Two Proteins in Nucleotide Excision Repair
Structure, 13, 2005
|
|
1TZ4
 | | [hPP19-23]-pNPY bound to DPC Micelles | | 分子名称: | neuropeptide Y,Pancreatic prohormone,neuropeptide Y | | 著者 | Lerch, M, Kamimori, H, Folkers, G, Aguilar, M.I, Beck-Sickinger, A.G, Zerbe, O. | | 登録日 | 2004-07-09 | | 公開日 | 2005-07-05 | | 最終更新日 | 2020-01-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes
in Structure and Membrane Binding
Biochemistry, 44, 2005
|
|
1TZ5
 | | [pNPY19-23]-hPP bound to DPC Micelles | | 分子名称: | Pancreatic prohormone,neuropeptide Y,Pancreatic prohormone | | 著者 | Lerch, M, Kamimori, H, Folkers, G, Aguilar, M.I, Beck-Sickinger, A.G, Zerbe, O. | | 登録日 | 2004-07-09 | | 公開日 | 2005-07-05 | | 最終更新日 | 2020-01-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes
in Structure and Membrane Binding
Biochemistry, 44, 2005
|
|
1KKC
 | | Crystal structure of Aspergillus fumigatus MnSOD | | 分子名称: | MANGANESE (II) ION, Manganese Superoxide Dismutase | | 著者 | Fluckiger, S, Mittl, P.R.E, Scapozza, L, Fijten, H, Folkers, G, Grutter, M.G, Blaser, K, Crameri, R. | | 登録日 | 2001-12-07 | | 公開日 | 2001-12-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution.
J.Immunol., 168, 2002
|
|
2C3B
 | | The Crystal Structure of Aspergillus fumigatus Cyclophilin reveals 3D Domain Swapping of a Central Element | | 分子名称: | PPIASE, SULFATE ION | | 著者 | Limacher, A, Kloer, D.P, Fluckiger, S, Folkers, G, Crameri, R, Scapozza, L. | | 登録日 | 2005-10-05 | | 公開日 | 2006-01-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Crystal Structure of Aspergillus Fumigatus Cyclophilin Reveals 3D Domain Swapping of a Central Element
Structure, 14, 2006
|
|
2AQ0
 | | Solution structure of the human homodimeric dna repair protein XPF | | 分子名称: | DNA repair endonuclease XPF | | 著者 | Das, D, Tripsianes, K, Folkers, G, Jaspers, N.G, Hoeijmakers, J.H, Kaptein, R, Boelens, R. | | 登録日 | 2005-08-17 | | 公開日 | 2006-10-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The HhH domain of the human DNA repair protein XPF forms stable homodimers
Proteins, 70, 2008
|
|
1OF1
 | | KINETICS AND CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (SOUTH)-METHANOCARBA-THYMIDINE | | 分子名称: | (SOUTH)-METHANOCARBA-THYMIDINE, SULFATE ION, THYMIDINE KINASE | | 著者 | Claus, M.T, Schelling, P, Folkers, G, Marquez, V.E, Scapozza, L, Schulz, G.E. | | 登録日 | 2003-04-03 | | 公開日 | 2004-06-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Biochemical and Structural Characterization of (South)-Methanocarbathymidine that Specifically Inhibits Growth of Herpes Simplex Virus Type 1 Thymidine Kinase-Transduced Osteosarcoma Cells
J.Biol.Chem., 279, 2004
|
|
3VTK
 | |
2VTK
 | |
1VTK
 | |
3F0T
 | | Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with N-methyl-DHBT | | 分子名称: | N-Methyl-6-(1,3-dihydroxy-isobutyl)thymine, SULFATE ION, Thymidine kinase | | 著者 | Pernot, L, Perozzo, R, Westermaier, Y, Martic, M, Ametamey, S, Scapozza, L. | | 登録日 | 2008-10-26 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.
Nucleosides Nucleotides Nucleic Acids, 30, 2011
|
|
1E2I
 | | The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography | | 分子名称: | 9-HYDROXYPROPYLADENINE, R-ISOMER, S-ISOMER, ... | | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | | 登録日 | 2000-05-23 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins, 41, 2000
|
|
1E2K
 | | Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine | | 分子名称: | 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE | | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | | 登録日 | 2000-05-23 | | 公開日 | 2000-08-19 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
|
|
1E2J
 | | The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography | | 分子名称: | SULFATE ION, THYMIDINE, THYMIDINE KINASE | | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | | 登録日 | 2000-05-23 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins: Struct.,Funct., Genet., 41, 2000
|
|
1E2H
 | | The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography | | 分子名称: | SULFATE ION, THYMIDINE KINASE | | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | | 登録日 | 2000-05-23 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography
Proteins: Struct.,Funct., Genet., 41, 2000
|
|
1E2N
 | | HPT + HMTT | | 分子名称: | 6-{[4-(HYDROXYMETHYL)-5-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDIN-5-YL]METHYL}-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE | | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | | 登録日 | 2000-05-23 | | 公開日 | 2001-03-31 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase
Protein Sci., 10, 2001
|
|
1E2P
 | | Thymidine kinase, DHBT | | 分子名称: | 6-[3-HYDROXY-2-(HYDROXYMETHYL)PROPYL]-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE, SULFATE ION, THYMIDINE KINASE | | 著者 | Schulz, G.E, Kessler, U. | | 登録日 | 2000-05-23 | | 公開日 | 2001-04-26 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase
Protein Sci., 10, 2001
|
|
1E2L
 | | Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine | | 分子名称: | 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE | | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | | 登録日 | 2000-05-23 | | 公開日 | 2000-08-18 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
|
|
1E2M
 | | HPT + HMTT | | 分子名称: | 6-HYDROXYPROPYLTHYMINE, SULFATE ION, THYMIDINE KINASE | | 著者 | Vogt, J, Scapozza, L, Schulz, G.E. | | 登録日 | 2000-05-23 | | 公開日 | 2001-03-31 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase
Protein Sci., 10, 2001
|
|
2JPD
 | | Solution structure of the ERCC1 central domain | | 分子名称: | DNA excision repair protein ERCC-1 | | 著者 | Tripsianes, K, Folkers, G, Zheng, C, Das, D, Grinstead, J.S, Kaptein, R, Boelens, R. | | 登録日 | 2007-05-06 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization
Nucleic Acids Res., 35, 2007
|
|
2KEK
 | | Solution structure of a dimer of LAC repressor DNA-binding domain complexed to its natural operator O3 | | 分子名称: | DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*GP*AP*GP*CP*GP*CP*AP*AP*CP*GP*CP*AP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*TP*TP*GP*CP*GP*TP*TP*GP*CP*GP*CP*TP*CP*AP*CP*TP*GP*CP*CP*G)-3'), Lactose operon repressor | | 著者 | Romanuka, J, Folkers, G, Biris, N, Tishchenko, E, Wienk, H, Kaptein, R, Boelens, R. | | 登録日 | 2009-01-30 | | 公開日 | 2009-05-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes.
J.Mol.Biol., 390, 2009
|
|
2KEI
 | | Refined Solution Structure of a Dimer of LAC repressor DNA-Binding domain complexed to its natural operator O1 | | 分子名称: | DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3'), Lactose operon repressor | | 著者 | Romanuka, J, Folkers, G, Biris, N, Tishchenko, E, Wienk, H, Kaptein, R, Boelens, R. | | 登録日 | 2009-01-30 | | 公開日 | 2009-05-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes.
J.Mol.Biol., 390, 2009
|
|
2KEJ
 | | Solution structure of a dimer of LAC repressor DNA-binding domain complexed to its natural operator O2 | | 分子名称: | DNA (5'-D(*GP*AP*AP*AP*TP*GP*TP*GP*AP*GP*CP*GP*AP*GP*TP*AP*AP*CP*AP*AP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*TP*TP*GP*TP*TP*AP*CP*TP*CP*GP*CP*TP*CP*AP*CP*AP*TP*TP*TP*C)-3'), Lactose operon repressor | | 著者 | Romanuka, J, Folkers, G, Biris, N, Tishchenko, E, Wienk, H, Kaptein, R, Boelens, R. | | 登録日 | 2009-01-30 | | 公開日 | 2009-05-19 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes.
J.Mol.Biol., 390, 2009
|
|
