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5I4Z
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BU of 5i4z by Molmil
Structure of apo OmoMYC
分子名称: CHLORIDE ION, GLYCEROL, Myc proto-oncogene protein, ...
著者Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C.
登録日2016-02-13
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
Oncogene, 36, 2017
5I50
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BU of 5i50 by Molmil
Structure of OmoMYC bound to double-stranded DNA
分子名称: DNA (5'-D(P*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*CP*TP*AP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*CP*GP*GP*GP*TP*G)-3'), Myc proto-oncogene protein
著者Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C.
登録日2016-02-13
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
Oncogene, 36, 2017
7ZTL
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BU of 7ztl by Molmil
Crystal structure of a covalently linked Aurora-A N-Myc complex
分子名称: 4-(3-hydroxy-3-oxopropylamino)-4-oxidanylidene-butanoic acid, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ...
著者Diebold, M, Schindelin, H.
登録日2022-05-11
公開日2023-01-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a covalently linked Aurora-A-MYCN complex.
Acta Crystallogr D Struct Biol, 79, 2023
7AZW
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BU of 7azw by Molmil
Crystal structure of the MIZ1-BTB-domain
分子名称: GLYCEROL, Zinc finger and BTB domain-containing protein 17 isoform X1
著者Orth, B, Sander, B, Diederichs, K, Lorenz, S.
登録日2020-11-17
公開日2021-06-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1.
Structure, 29, 2021
7AZX
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BU of 7azx by Molmil
Crystal structure of the MIZ1-BTB-domain in complex with a HUWE1-derived peptide
分子名称: E3 ubiquitin-protein ligase HUWE1, Zinc finger and BTB domain-containing protein 17 isoform X1
著者Orth, B, Sander, B, Diederichs, K, Lorenz, S.
登録日2020-11-17
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1.
Structure, 29, 2021
5LP8
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BU of 5lp8 by Molmil
Crystal structure of an asymmetric dimer of the ubiquitin ligase HUWE1
分子名称: E3 ubiquitin-protein ligase HUWE1
著者Sander, B, Lorenz, S.G.
登録日2016-08-12
公開日2017-02-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A conformational switch regulates the ubiquitin ligase HUWE1.
Elife, 6, 2017
5G1X
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BU of 5g1x by Molmil
Crystal structure of Aurora-A kinase in complex with N-Myc
分子名称: ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, MAGNESIUM ION, ...
著者Richards, M.W, Burgess, S.G, Bayliss, R.
登録日2016-03-31
公開日2016-11-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural Basis of N-Myc Binding by Aurora-A and its Destabilization by Kinase Inhibitors
Proc.Natl.Acad.Sci.USA, 113, 2016
4J8N
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BU of 4j8n by Molmil
Aurora A Kinase Apo
分子名称: Aurora kinase A
著者Meyerowitz, J.G, Gustafson, W.C, Shokat, K.M, Weiss, W.A.
登録日2013-02-14
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.135 Å)
主引用文献Drugging MYCN through an Allosteric Transition in Aurora Kinase A.
Cancer Cell, 26, 2014
4J8M
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BU of 4j8m by Molmil
Aurora A in complex with CD532
分子名称: 1,2-ETHANEDIOL, 1-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea, Aurora kinase A, ...
著者Meyerowitz, J.G, Gustafson, W.C, Shokat, K.M, Weiss, W.A.
登録日2013-02-14
公開日2014-09-10
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.853 Å)
主引用文献Drugging MYCN through an Allosteric Transition in Aurora Kinase A.
Cancer Cell, 26, 2014
8ONQ
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BU of 8onq by Molmil
Structure of the amyloid-forming peptide Ac-EFIAWL from human GLP-1
分子名称: Peptide Ac-EFIAWL from hGLP-1
著者Durvanger, Z.
登録日2023-04-03
公開日2023-08-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANH
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BU of 8anh by Molmil
Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 30% acetonitrile
分子名称: ACETONITRILE, Peptide LYIQWL from Tc5b, trifluoroacetic acid
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANM
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BU of 8anm by Molmil
Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from water
分子名称: Peptide LYIQWL from Tc5b
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANN
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BU of 8ann by Molmil
Structure of the amyloid-forming peptide LFIEWL from exendin-4, grown from acetonitrile / water
分子名称: Peptide LFIEWL from exendin-4
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANL
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BU of 8anl by Molmil
Structure of the amyloid-forming peptide LFIEWL from exendin-4, grown from water
分子名称: Peptide LFIEWL from exendin-4
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANI
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BU of 8ani by Molmil
Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 10% ethanol
分子名称: ETHANOL, Peptide LYIQWL from Tc5b, trifluoroacetic acid
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANG
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BU of 8ang by Molmil
Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 30% ethanol
分子名称: ETHANOL, Peptide LYIQWL from Tc5b
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANJ
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BU of 8anj by Molmil
Structure of the amyloid-forming peptide DFINWL from human GLP-2
分子名称: Peptide DFINWL from human GLP-2
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023
8ANK
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BU of 8ank by Molmil
Structure of the amyloid-forming peptide pEFIAWL from human GLP-1
分子名称: Peptide pEFIAWL from hGLP-1
著者Durvanger, Z.
登録日2022-08-05
公開日2023-08-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation.
Nat Commun, 14, 2023

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