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4J8N

Aurora A Kinase Apo

Summary for 4J8N
Entry DOI10.2210/pdb4j8n/pdb
Related4J8M
DescriptorAurora kinase A (2 entities in total)
Functional Keywordsaurora a, kinase domain, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, microtubule organizing center, centrosome : O14965
Total number of polymer chains4
Total formula weight129436.49
Authors
Meyerowitz, J.G.,Gustafson, W.C.,Shokat, K.M.,Weiss, W.A. (deposition date: 2013-02-14, release date: 2014-09-10, Last modification date: 2024-02-28)
Primary citationGustafson, W.C.,Meyerowitz, J.G.,Nekritz, E.A.,Chen, J.,Benes, C.,Charron, E.,Simonds, E.F.,Seeger, R.,Matthay, K.K.,Hertz, N.T.,Eilers, M.,Shokat, K.M.,Weiss, W.A.
Drugging MYCN through an Allosteric Transition in Aurora Kinase A.
Cancer Cell, 26:414-427, 2014
Cited by
PubMed: 25175806
DOI: 10.1016/j.ccr.2014.07.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.135 Å)
Structure validation

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