1V6C
| Crystal Structure of Psychrophilic Subtilisin-like Protease Apa1 from Antarctic Psychrotroph Pseudoalteromonas sp. AS-11 | 分子名称: | CALCIUM ION, SULFATE ION, alkaline serine protease, ... | 著者 | Dong, D, Ihara, T, Motoshima, H, Watanabe, K. | 登録日 | 2003-11-28 | 公開日 | 2004-12-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Psychrophilic Subtilisin-like Protease Apa1 from Antarctic Psychrotroph Pseudoalteromonas sp. AS-11 To be Published
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5ID6
| Structure of Cpf1/RNA Complex | 分子名称: | Cpf1, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3') | 著者 | Dong, D, Ren, K, Qiu, X, Wang, J, Huang, Z. | 登録日 | 2016-02-24 | 公開日 | 2016-04-27 | 最終更新日 | 2016-05-11 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | The crystal structure of Cpf1 in complex with CRISPR RNA Nature, 532, 2016
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1WVM
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1Y9Z
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2LU0
| NMR solution structure of the kappa-zeta region of S.cerevisiae group II intron ai5(gamma) | 分子名称: | RNA (49-MER) | 著者 | Donghi, D, Pechlaner, M, Finazzo, C, Knobloch, B, Sigel, R.K.O. | 登録日 | 2012-06-05 | 公開日 | 2013-04-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The structural stabilization of the kappa three-way junction by Mg(II) represents the first step in the folding of a group II intron. Nucleic Acids Res., 41, 2013
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8BZN
| SARS-CoV-2 non-structural protein 10 (nsp10) variant T102I | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, Replicase polyprotein 1ab, ... | 著者 | Wang, H, Rizvi, S.R.A, Dong, D, Lou, J, Wang, Q, Sopipong, W, Najar, F, Agarwal, P.K, Kozielski, F, Haider, S. | 登録日 | 2022-12-15 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16. Elife, 12, 2023
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6NZS
| Dextranase AoDex KQ11 | 分子名称: | Dextranase | 著者 | Ren, W, Yan, W, Gu, L, Feng, Y, Dong, D, Wang, S, Wang, C, Lyu, M. | 登録日 | 2019-02-14 | 公開日 | 2019-02-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of thermophilic dextranase from Thermoanaerobacter pseudethanolicus To Be Published
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7ORW
| Non-structural protein 10 (nsp10) from SARS CoV-2 in complex with fragment VT00265 | 分子名称: | 1H-benzimidazol-4-amine, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Talibov, V.O, Kozielski, F, Sele, C, Lou, J, Dong, D, Wang, Q, Shi, X, Nyblom, M, Rogstam, A, Krojer, T, Knecht, W, Fisher, S.Z. | 登録日 | 2021-06-06 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. Rsc Chem Biol, 3, 2022
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7ORU
| Non-structural protein 10 (nsp10) from SARS CoV-2 in complex with fragment VT00221 | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Talibov, V.O, Kozielski, F, Sele, C, Lou, J, Dong, D, Wang, Q, Shi, X, Nyblom, M, Rogstam, A, Krojer, T, Knecht, W, Fisher, S.Z. | 登録日 | 2021-06-06 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. Rsc Chem Biol, 3, 2022
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7ORV
| Non-structural protein 10 (nsp10) from SARS CoV-2 in complex with fragment VT00239 | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Talibov, V.O, Kozielski, F, Sele, C, Lou, J, Dong, D, Wang, Q, Shi, X, Nyblom, M, Rogstam, A, Krojer, T, Knecht, W, Fisher, S.Z. | 登録日 | 2021-06-06 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. Rsc Chem Biol, 3, 2022
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7ORR
| Non-structural protein 10 (nsp10) from SARS CoV-2 in complex with fragment VT00022 | 分子名称: | 4-PHENYL-1H-IMIDAZOLE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Talibov, V.O, Kozielski, F, Sele, C, Lou, J, Dong, D, Wang, Q, Shi, X, Nyblom, M, Rogstam, A, Krojer, T, Knecht, W, Fisher, S.Z. | 登録日 | 2021-06-06 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. Rsc Chem Biol, 3, 2022
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2M57
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6JXR
| Structure of human T cell receptor-CD3 complex | 分子名称: | T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, T-cell surface glycoprotein CD3 delta chain, ... | 著者 | Dong, D, Zheng, L, Lin, J, Zhu, Y, Li, N, Zhang, B, Xie, S, Zheng, J, Wang, Y, Gao, N, Huang, Z. | 登録日 | 2019-04-24 | 公開日 | 2019-09-11 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of assembly of the human T cell receptor-CD3 complex. Nature, 573, 2019
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5XBL
| Structure of nuclease in complex with associated protein | 分子名称: | Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER) | 著者 | Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z. | 登録日 | 2017-03-20 | 公開日 | 2017-06-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.052 Å) | 主引用文献 | Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein Nature, 546, 2017
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7BZJ
| The Discovery of Benzhydrol-Oxaborole Hybrid Derivatives as Leucyl-tRNA Synthetase Inhibitors | 分子名称: | Leucine--tRNA ligase, [(1~{R},5~{R},6~{S},8~{R})-8-(6-aminopurin-9-yl)-4'-[(~{R})-oxidanyl-[4-(2-oxidanylidenepropylsulfanyl)phenyl]methyl]spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,7'-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-triene]-6-yl]methoxy-tris(oxidanyl)phosphanium | 著者 | Liu, R.J, Li, H, Wang, E.D, Zhou, H. | 登録日 | 2020-04-28 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors. Bioorg.Med.Chem., 29, 2021
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6UGJ
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6UGG
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6UGI
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