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3L4B
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BU of 3l4b by Molmil
Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima
分子名称: ADENOSINE MONOPHOSPHATE, TrkA K+ Channel protein TM1088A, TrkA K+ Channel protein TM1088B, ...
著者Deller, M.C, Johnson, H.A, Miller, M, Spraggon, G, Wilson, I.A, Lesley, S.A, Joint Center for Structural Genomics (JCSG)
登録日2009-12-18
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima
To be Published
1EVS
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BU of 1evs by Molmil
CRYSTAL STRUCTURE OF HUMAN ONCOSTATIN M
分子名称: ONCOSTATIN M
著者Deller, M.C, Hudson, K.R, Ikemizu, S, Bravo, J, Jones, E.Y, Heath, J.K.
登録日2000-04-20
公開日2000-09-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure and functional dissection of the cytostatic cytokine oncostatin M.
Structure Fold.Des., 8, 2000
3JXO
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BU of 3jxo by Molmil
Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima
分子名称: TrkA-N domain protein
著者Deller, M.C, Johnson, H.A, Miller, M, Spraggon, G, Wilson, I.A, Lesley, S.A, Joint Center for Structural Genomics (JCSG)
登録日2009-09-20
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima
To be Published
8UV0
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BU of 8uv0 by Molmil
Discovery of (4-Pyrazolyl)-2-Aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
分子名称: 1-{(4M)-4-[2-{[1-(cyclopropanesulfonyl)piperidin-4-yl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrazol-1-yl}-2-methylpropan-2-ol, Cyclin-dependent kinase 2
著者Deller, M.C, Epling, L.B.
登録日2023-11-02
公開日2024-02-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2.
J.Med.Chem., 67, 2024
8E1X
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BU of 8e1x by Molmil
FGFR2 kinase domain in complex with a Pyrazolo[1,5-a]pyrimidine analog (Compound 29)
分子名称: (5M)-N-methyl-5-{(6M,8S)-5-{[(3S)-oxolan-3-yl]amino}-6-[1-(propan-2-yl)-1H-pyrazol-3-yl]pyrazolo[1,5-a]pyrimidin-3-yl}pyridine-3-carboxamide, Fibroblast growth factor receptor 2
著者Lei, H.-T, Epling, L.B, Deller, M.C.
登録日2022-08-11
公開日2022-11-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3.
J.Med.Chem., 65, 2022
5UFV
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BU of 5ufv by Molmil
Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*)
分子名称: COPPER (II) ION, Glycoside hydrolase family 61 protein
著者Span, E.A, Deller, M.C, Marletta, M.A.
登録日2017-01-05
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase.
ACS Chem. Biol., 12, 2017
6C9U
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BU of 6c9u by Molmil
Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab)
分子名称: 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Heavy chain of Fab 1B2, ...
著者Deis, L.N, Li, X, Mathews, I.I, Khosla, C.
登録日2018-01-28
公開日2018-05-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module.
J. Am. Chem. Soc., 140, 2018
1VLQ
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BU of 1vlq by Molmil
Crystal structure of Acetyl xylan esterase (TM0077) from Thermotoga maritima at 2.10 A resolution
分子名称: GLYCEROL, acetyl xylan esterase
著者Joint Center for Structural Genomics (JCSG)
登録日2004-08-09
公開日2004-08-24
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.
Proteins, 80, 2012
6OFO
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BU of 6ofo by Molmil
Crystal structure of split green fluorescent protein (GFP); s10 circular permutant (194-195)
分子名称: Green fluorescent protein (GFP); s10 circular permutant (194-195)
著者Lin, C.-Y, Romei, M.G, Deller, M.C, Doukov, T.I, Boxer, S.G.
登録日2019-03-31
公開日2019-07-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins.
J.Am.Chem.Soc., 141, 2019
4NCO
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BU of 4nco by Molmil
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ...
著者Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A.
登録日2013-10-24
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
4RBO
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BU of 4rbo by Molmil
Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolution
分子名称: 5'-D(*CP*TP*TP*GP*AP*AP*TP*GP*GP*GP*CP*C)-3', 5'-D(*GP*GP*CP*CP*CP*AP*TP*TP*CP*AP*AP*G)-3', Putative homeobox protein NANOGP8
著者Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)
登録日2014-09-12
公開日2014-10-01
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.
Proc.Natl.Acad.Sci.USA, 112, 2015
2RA9
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BU of 2ra9 by Molmil
Crystal structure of a duf1285 family protein (sbal_2486) from shewanella baltica os155 at 1.40 A resolution
分子名称: 1,2-ETHANEDIOL, SODIUM ION, Uncharacterized protein DUF1285
著者Joint Center for Structural Genomics (JCSG)
登録日2007-09-14
公開日2007-10-16
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.
Acta Crystallogr.,Sect.F, 66, 2010
2RE3
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BU of 2re3 by Molmil
CRYSTAL STRUCTURE OF a DUF1285 family protein (SPO_0140) FROM SILICIBACTER POMEROYI DSS-3 AT 2.50 A RESOLUTION
分子名称: GLYCEROL, Uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2007-09-25
公開日2007-10-09
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.
Acta Crystallogr.,Sect.F, 66, 2010
2FG0
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BU of 2fg0 by Molmil
Crystal structure of a putative gamma-d-glutamyl-l-diamino acid endopeptidase (npun_r0659) from nostoc punctiforme pcc 73102 at 1.79 A resolution
分子名称: COG0791: Cell wall-associated hydrolases (invasion-associated proteins), GLYCEROL
著者Joint Center for Structural Genomics (JCSG)
登録日2005-12-20
公開日2006-01-10
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis of Murein Peptide Specificity of a gamma-D-Glutamyl-L-Diamino Acid Endopeptidase.
Structure, 17, 2009
2EVR
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BU of 2evr by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE (NPUN_R0659) FROM NOSTOC PUNCTIFORME PCC 73102 AT 1.60 A RESOLUTION
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COG0791: Cell wall-associated hydrolases (invasion-associated proteins), ...
著者Joint Center for Structural Genomics (JCSG)
登録日2005-10-31
公開日2005-11-22
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis of Murein Peptide Specificity of a gamma-D-Glutamyl-L-Diamino Acid Endopeptidase.
Structure, 17, 2009
2QTP
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BU of 2qtp by Molmil
Crystal structure of a duf1185 family protein (spo0826) from silicibacter pomeroyi dss-3 at 2.10 A resolution
分子名称: Uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2007-08-02
公開日2007-08-21
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
5CD5
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BU of 5cd5 by Molmil
Crystal structure of an immature VRC01-class antibody DRVIA7 from a Chinese donor bound to clade A/E HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 93TH057 HIV-1 gp120 core, ...
著者Kong, L, Wilson, I.A.
登録日2015-07-03
公開日2016-04-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.396 Å)
主引用文献Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5C7K
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BU of 5c7k by Molmil
Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ...
著者Kong, L, Stanfield, R.L, Wilson, I.A.
登録日2015-06-24
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.6019 Å)
主引用文献Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Acta Crystallogr.,Sect.D, 71, 2015
5CD3
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BU of 5cd3 by Molmil
Structure of immature VRC01-class antibody DRVIA7
分子名称: DRVIA7 Heavy Chain, DRVIA7 Light Chain
著者Kong, L, Wilson, I.A.
登録日2015-07-02
公開日2016-04-06
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
3B77
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BU of 3b77 by Molmil
Crystal structure of a ph domain containing bacterial protein (exig_2160) from exiguobacterium sibiricum 255-15 at 2.42 A resolution
分子名称: Uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2007-10-30
公開日2007-11-13
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.
J.Mol.Biol., 396, 2010
3BYQ
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BU of 3byq by Molmil
Crystal structure of a duf1185 family protein (bb2672) from bordetella bronchiseptica rb50 at 1.70 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, TETRAETHYLENE GLYCOL, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2008-01-16
公開日2008-01-29
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
3BY7
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BU of 3by7 by Molmil
CRYSTAL STRUCTURE OF A PROTEIN STRUCTURALLY SIMILAR TO SM/LSM-LIKE RNA-BINDING PROTEINS (JCVI_PEP_1096686650277) FROM UNCULTURED MARINE ORGANISM AT 2.60 A RESOLUTION
分子名称: uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-01-15
公開日2008-01-29
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.
Proteins, 75, 2009
3BOS
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BU of 3bos by Molmil
Crystal structure of a putative dna replication regulator HDA (SAMA_1916) from Shewanella amazonensis sb2b at 1.75 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2007-12-17
公開日2008-01-15
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A structural basis for the regulatory inactivation of DnaA.
J.Mol.Biol., 385, 2009
4G6A
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BU of 4g6a by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody AP33
分子名称: AP33 Heavy Chain, AP33 Light chain, E2 peptide
著者Kong, L, Wilson, I.A, Law, M.
登録日2012-07-18
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33.
J.Virol., 86, 2012
4JM2
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BU of 4jm2 by Molmil
Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab
分子名称: 17b Heavy chain, 17b Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kong, L, Wilson, I.A.
登録日2013-03-13
公開日2013-05-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nat.Struct.Mol.Biol., 20, 2013

 

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