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SARS-CoV2 Omicron BA.1 spike in complex with CAB-A17 antibody
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CAB-A17 antibody (HC), ...
著者	Das, H, Hallberg, B.M.
登録日	2022-12-22
公開日	2024-05-22
実験手法	ELECTRON MICROSCOPY (2.56 Å)
主引用文献	SARS-CoV-2 omicron Spike (RBD) in complex with CAB-A17 antibody To Be Published

8P5M

SARS-CoV-2 Spike RBD in complex with Mab-23 (Fab)
分子名称:	Mab-23 (Heavy chain variable domain), Mab-23 (Light chain variable domain), Spike protein S1
著者	Das, H, Hallberg, B.M.
登録日	2023-05-24
公開日	2024-06-05
実験手法	ELECTRON MICROSCOPY (2.8 Å)
主引用文献	SARS-CoV-2 Spike RBD in complex with Mab-23 (Fab domains) To Be Published

7NS6

SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Fu2 nanobody, Spike glycoprotein,Fibritin, ...
著者	Das, H, Hallberg, B.M.
登録日	2021-03-05
公開日	2022-02-02
実験手法	ELECTRON MICROSCOPY (3.18 Å)
主引用文献	A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun, 13, 2022

7ZC4

Cryo-EM structure of POLRMT mutant.
分子名称:	DNA-directed RNA polymerase, mitochondrial
著者	Das, H, Hallberg, B.M.
登録日	2022-03-25
公開日	2023-02-01
実験手法	ELECTRON MICROSCOPY (3.24 Å)
主引用文献	Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022

7PZP

Mitochondrial DNA dependent RNA polymerase homodimer.
分子名称:	DNA-directed RNA polymerase, mitochondrial
著者	Das, H, Hallberg, B.M.
登録日	2021-10-13
公開日	2022-09-28
最終更新日	2022-10-05
実験手法	ELECTRON MICROSCOPY (3.5 Å)
主引用文献	Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022

7PZR

Cryo-EM structure of POLRMT in free form.
分子名称:	DNA-directed RNA polymerase, mitochondrial
著者	Das, H, Hallberg, B.M.
登録日	2021-10-13
公開日	2022-11-16
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022

7NLL

SARS-CoV-2 Spike RBD (dimer) in complex with two Fu2 nanobodies
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Fu2, Spike protein S1
著者	Das, H, Hallberg, B.M.
登録日	2021-02-22
公開日	2022-02-02
最終更新日	2023-09-27
実験手法	ELECTRON MICROSCOPY (2.89 Å)
主引用文献	A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun, 13, 2022

8V4F

Model and map from local refinement of a CAB-A17 - Omicron Ba.1 spike complex
分子名称:	CAB-A17 variable heavy-chain, CAB-A17 variable light chain, Spike protein S1
著者	Hallberg, B.M, Das, H.
登録日	2023-11-29
公開日	2024-06-05
実験手法	ELECTRON MICROSCOPY (2.68 Å)
主引用文献	Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies. Cell Rep Med, 2024

7B18

SARS-CoV-spike bound to two neutralising nanobodies
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 VHH E, ...
著者	Hallberg, B.M, Das, H.
登録日	2020-11-24
公開日	2021-04-28
実験手法	ELECTRON MICROSCOPY (2.62 Å)
主引用文献	Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021

7B17

SARS-CoV-spike RBD bound to two neutralising nanobodies.
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama,SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama, Spike protein S1
著者	Hallberg, B.M, Das, H.
登録日	2020-11-23
公開日	2021-02-10
最終更新日	2022-12-21
実験手法	ELECTRON MICROSCOPY (4.01 Å)
主引用文献	Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021

7B14

Nanobody E bound to Spike-RBD in a localized reconstruction
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2, Spike protein S1
著者	Hallberg, B.M, Das, H.
登録日	2020-11-23
公開日	2021-04-28
最終更新日	2022-12-21
実験手法	ELECTRON MICROSCOPY (3.79 Å)
主引用文献	Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021

7A25

Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者	Hallberg, B.M, Das, H.
登録日	2020-08-16
公開日	2020-11-25
実験手法	ELECTRON MICROSCOPY (3.06 Å)
主引用文献	Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nat Commun, 11, 2020

8A99

SARS Cov2 Spike in 1-up conformation complex with Fab47
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ...
著者	Hallberg, B.M, Das, H.
登録日	2022-06-28
公開日	2023-05-10
最終更新日	2023-09-27
実験手法	ELECTRON MICROSCOPY (2.5 Å)
主引用文献	Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023

8A94

SARS CoV2 Spike in the 2-up state in complex with Fab47.
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain Variable domain), ...
著者	Hallberg, B.M, Das, H.
登録日	2022-06-27
公開日	2023-05-03
最終更新日	2023-07-26
実験手法	ELECTRON MICROSCOPY (2.4 Å)
主引用文献	Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023

8A95

SARS Cov2 Spike RBD in complex with Fab47
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ...
著者	Hallberg, B.M, Das, H.
登録日	2022-06-27
公開日	2023-08-16
実験手法	ELECTRON MICROSCOPY (2.64 Å)
主引用文献	Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023

7KSG

SARS-CoV-2 spike in complex with nanobodies E
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 glycoprotein, Spike glycoprotein
著者	Hallberg, B.M, Das, H.
登録日	2020-11-22
公開日	2021-01-20
最終更新日	2021-06-30
実験手法	ELECTRON MICROSCOPY (3.33 Å)
主引用文献	Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021

6ZXN

Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing nanobodies (Ty1)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Ty1, ...
著者	Hallberg, B.M, Das, H.
登録日	2020-07-30
公開日	2020-09-23
実験手法	ELECTRON MICROSCOPY (2.93 Å)
主引用文献	An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction. Nat Commun, 11, 2020

7A29

Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralising sybody (Sb23), ...
著者	Hallberg, B.M, Das, H.
登録日	2020-08-16
公開日	2020-10-21
最終更新日	2020-11-18
実験手法	ELECTRON MICROSCOPY (2.94 Å)
主引用文献	Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nat Commun, 11, 2020

8A96

SARS Cov2 Spike RBD in complex with Fab47
分子名称:	Fab47 Heavy chain (variable domain), Fab47 Light chain (variable domain), Spike protein S1
著者	Hallberg, B.M, Das, H.
登録日	2022-06-27
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023

7KN5

Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
登録日	2020-11-04
公開日	2021-01-20
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.87 Å)
主引用文献	Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021

7KN6

Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
著者	Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
登録日	2020-11-04
公開日	2021-01-20
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021

7KN7

Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH W and antibody Fab CC12.3
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
著者	Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
登録日	2020-11-04
公開日	2021-01-20
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.73 Å)
主引用文献	Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021

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表示件数:	22
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