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6L92
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BU of 6l92 by Molmil
A basket type G-quadruplex in WNT DNA promoter
分子名称: DNA (5'-D(*GP*GP*GP*CP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3')
著者Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C.
登録日2019-11-08
公開日2019-12-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter.
Nucleic Acids Res., 48, 2020
6L8M
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BU of 6l8m by Molmil
WNT DNA promoter mutant G-quadruplex
分子名称: DNA (5'-D(*GP*GP*GP*TP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3')
著者Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C.
登録日2019-11-06
公開日2019-12-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter.
Nucleic Acids Res., 48, 2020
6NLH
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BU of 6nlh by Molmil
Structure of human triose phosphate isomerase R189A
分子名称: BROMIDE ION, PHOSPHATE ION, SODIUM ION, ...
著者Richards, K.R, Roland, B.P, Palladino, M.J, VanDemark, A.P.
登録日2019-01-08
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
6O2L
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BU of 6o2l by Molmil
NMR structure of the 2:1 complex of a carbazole derivative BMVC bound to c-MYC G-quadruplex
分子名称: 3,6-bis[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-9H-carbazole, DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3')
著者Lin, C, Liu, W, Yang, D.
登録日2019-02-24
公開日2019-10-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition.
Nucleic Acids Res., 47, 2019
8TH1
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BU of 8th1 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein D3L mutant
分子名称: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-13
公開日2023-12-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH6
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BU of 8th6 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide
分子名称: 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-14
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH7
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BU of 8th7 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide
分子名称: Caprin-1, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-14
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH5
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BU of 8th5 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant
分子名称: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-13
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
6JJ0
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BU of 6jj0 by Molmil
NMR structure of the 1:1 complex of a carbazole derivative BMVC bound to c-MYC G-quadruplex
分子名称: 3,6-bis[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-9H-carbazole, MycG4
著者Liu, W, Lin, C, Yang, D.
登録日2019-02-24
公開日2019-10-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition.
Nucleic Acids Res., 47, 2019

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件を2024-07-17に公開中

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