6D8C
| Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Iwamoto, D.V, Huehn, A.R, Simon, B, Huet-Calderwood, C, Baldassarre, M, Sindelar, C.V, Calderwood, D.A. | 登録日 | 2018-04-26 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat. Struct. Mol. Biol., 25, 2018
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4BBK
| Structural and functional characterisation of the kindlin-1 pleckstrin homology domain | 分子名称: | FERMITIN FAMILY HOMOLOG 1, GLYCEROL | 著者 | Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C. | 登録日 | 2012-09-25 | 公開日 | 2012-11-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain J.Biol.Chem., 287, 2012
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3F6Q
| Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain | 分子名称: | IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ... | 著者 | Chiswell, B.P, Calderwood, D.A, Boggon, T.J. | 登録日 | 2008-11-06 | 公開日 | 2008-12-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structural basis of integrin-linked kinase-PINCH interactions. Proc.Natl.Acad.Sci.USA, 105, 2008
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3IXE
| Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase | 分子名称: | Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 2, ZINC ION | 著者 | Chiswell, B.P, Stiegler, A.L, Boggon, T.J, Calderwood, D.A. | 登録日 | 2009-09-03 | 公開日 | 2009-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase. J.Struct.Biol., 170, 2010
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4HI9
| 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974 | 分子名称: | IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ... | 著者 | Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J. | 登録日 | 2012-10-11 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.203 Å) | 主引用文献 | 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974 To be Published
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4HI8
| Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800 | 分子名称: | Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, PHOSPHATE ION, ... | 著者 | Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J. | 登録日 | 2012-10-11 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.203 Å) | 主引用文献 | Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800 To be Published
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1MK7
| CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA | 分子名称: | Integrin Beta3, TALIN | 著者 | Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | 登録日 | 2002-08-28 | 公開日 | 2003-01-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
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1MIX
| Crystal structure of a FERM domain of Talin | 分子名称: | Talin | 著者 | Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | 登録日 | 2002-08-23 | 公開日 | 2003-01-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural determinants of integrin recognition by talin Mol.Cell, 11, 2003
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1MIZ
| Crystal structure of an integrin beta3-talin chimera | 分子名称: | TALIN, integrin beta3 | 著者 | Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | 登録日 | 2002-08-23 | 公開日 | 2003-01-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural determinants of integrin recognition by talin Mol.Cell, 11, 2003
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1MK9
| CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA | 分子名称: | Integrin Beta3, TALIN | 著者 | Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | 登録日 | 2002-08-28 | 公開日 | 2003-01-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
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4EDL
| Crystal structure of beta-parvin CH2 domain | 分子名称: | 1,2-ETHANEDIOL, Beta-parvin | 著者 | Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J. | 登録日 | 2012-03-27 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for paxillin binding and focal adhesion targeting of beta-parvin. J.Biol.Chem., 287, 2012
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4EDM
| Crystal structure of beta-parvin CH2 domain | 分子名称: | 1,2-ETHANEDIOL, Beta-parvin | 著者 | Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J. | 登録日 | 2012-03-27 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for paxillin binding and focal adhesion targeting of beta-parvin. J.Biol.Chem., 287, 2012
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4DX8
| ICAP1 in complex with KRIT1 N-terminus | 分子名称: | BROMIDE ION, Integrin beta-1-binding protein 1, Krev interaction trapped protein 1 | 著者 | Liu, W, Draheim, K, Zhang, R, Calderwood, D.A, Boggon, T.J. | 登録日 | 2012-02-27 | 公開日 | 2013-01-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation. Mol.Cell, 49, 2013
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4DX9
| ICAP1 in complex with integrin beta 1 cytoplasmic tail | 分子名称: | Integrin beta-1, Integrin beta-1-binding protein 1 | 著者 | Liu, W, Draheim, K, Zhang, R, Calderwood, D.A, Boggon, T.J. | 登録日 | 2012-02-27 | 公開日 | 2013-01-09 | 最終更新日 | 2020-09-02 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation. Mol.Cell, 49, 2013
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4EDN
| Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif | 分子名称: | Beta-parvin, Paxillin, SULFATE ION | 著者 | Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J. | 登録日 | 2012-03-27 | 公開日 | 2012-08-08 | 最終更新日 | 2013-06-19 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for paxillin binding and focal adhesion targeting of beta-parvin. J.Biol.Chem., 287, 2012
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2KC1
| NMR structure of the F0 domain (residues 0-85) of the talin ferm domain | 分子名称: | MKIAA1027 protein | 著者 | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | 登録日 | 2008-12-13 | 公開日 | 2010-01-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. Embo J., 29, 2010
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2KMA
| NMR structure of the F0F1 double domain (residues 1-202) of the talin ferm domain | 分子名称: | Talin 1 | 著者 | Goult, B.T, Elliott, P.R, Bate, N, Roberts, G.C, Critchley, D.R, Barsukov, I.L. | 登録日 | 2009-07-25 | 公開日 | 2010-03-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. Embo J., 2010
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7LNY
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7LO0
| Structure of human ASF1a in complex with a TLK2 peptide | 分子名称: | Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2 | 著者 | Simon, B, Calderwood, D, Turk, B.E, Boggon, T.J. | 登録日 | 2021-02-08 | 公開日 | 2022-02-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. Nat Commun, 13, 2022
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4TVQ
| CCM3 in complex with CCM2 LD-like motif | 分子名称: | Cerebral cavernous malformations 2 protein, Cerebral cavernous malformations 3 protein | 著者 | Li, X, Zhang, R, Fisher, O.S, Boggon, T.J. | 登録日 | 2014-06-27 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation. J.Cell Biol., 208, 2015
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2BRQ
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2W0P
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7S47
| Integrin beta5(743-774)-linker-PAK4cat(D440N/S474E) | 分子名称: | Integrin beta-5, Isoform 2 of Serine/threonine-protein kinase PAK 4 chimera, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2021-09-08 | 公開日 | 2022-11-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4) Commun Biol, 5, 2022
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7S48
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7S46
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