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1DTH
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METALLOPROTEASE
分子名称: 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, ATROLYSIN C, CALCIUM ION, ...
著者Botos, I, Scapozza, L, Zhang, D, Liotta, L.A, Meyer, E.F.
登録日1996-02-12
公開日1997-02-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
3GXY
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Crystal structure of cyanovirin-n complexed to a synthetic hexamannoside
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ...
著者Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A.
登録日2009-04-03
公開日2009-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of the complexes of a potent anti-HIV protein cyanovirin-n and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
3GXZ
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Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9)
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ...
著者Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A.
登録日2009-04-03
公開日2009-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
1QZM
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BU of 1qzm by Molmil
alpha-domain of ATPase
分子名称: ATP-dependent protease La
著者Botos, I, Melnikov, E.E, Cherry, S, Khalatova, A.G, Rasulova, F.S, Tropea, J.E, Maurizi, M.R, Rotanova, T.V, Gustchina, A, Wlodawer, A.
登録日2003-09-17
公開日2004-05-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution.
J.Struct.Biol., 146
6U5Z
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Cryo-EM structure of E. coli LonA S679A
分子名称: Lon protease
著者Botos, I, Lountos, G.T, Weimin, W, Wlodawer, A.
登録日2019-08-28
公開日2020-02-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery
Curr Res Struct Biol, 1, 2020
1RR9
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Catalytic domain of E.coli Lon protease
分子名称: ATP-dependent protease La, SULFATE ION
著者Botos, I, Melnikov, E.E, Cherry, S, Tropea, J.E, Khalatova, A.G, Dauter, Z, Maurizi, M.R, Rotanova, T.V, Wlodawer, A, Gustchina, A.
登録日2003-12-08
公開日2003-12-23
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site
J.Biol.Chem., 279, 2004
1RRE
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BU of 1rre by Molmil
Crystal structure of E.coli Lon proteolytic domain
分子名称: ATP-dependent protease La, SULFATE ION
著者Botos, I, Melnikov, E.E, Cherry, S, Tropea, J.E, Khalatova, A.G, Rasulova, F, Dauter, Z, Maurizi, M.R, Rotanova, T.V, Wlodawer, A, Gustchina, A.
登録日2003-12-08
公開日2004-02-03
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site
J.Biol.Chem., 279, 2004
1Z0C
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Crystal Structure of A. fulgidus Lon proteolytic domain D508A mutant
分子名称: Putative protease La homolog type
著者Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A.
登録日2005-03-01
公開日2005-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases
J.Mol.Biol., 351, 2005
1Z0G
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Crystal Structure of A. fulgidus Lon proteolytic domain
分子名称: Putative protease La homolog type
著者Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A.
登録日2005-03-01
公開日2005-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases
J.Mol.Biol., 351, 2005
1Z0B
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BU of 1z0b by Molmil
Crystal Structure of A. fulgidus Lon proteolytic domain E506A mutant
分子名称: CALCIUM ION, Putative protease La homolog type
著者Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A.
登録日2005-03-01
公開日2005-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases
J.Mol.Biol., 351, 2005
1Z0E
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BU of 1z0e by Molmil
Crystal Structure of A. fulgidus Lon proteolytic domain
分子名称: Putative protease La homolog type
著者Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A.
登録日2005-03-01
公開日2005-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases
J.Mol.Biol., 351, 2005
1Z0W
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Crystal Structure of A. fulgidus Lon proteolytic domain at 1.2A resolution
分子名称: CALCIUM ION, Putative protease La homolog type
著者Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A.
登録日2005-03-02
公開日2005-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases
J.Mol.Biol., 351, 2005
5IV8
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BU of 5iv8 by Molmil
The LPS Transporter LptDE from Klebsiella pneumoniae, core complex
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LPS biosynthesis protein, LPS-assembly lipoprotein LptE
著者Botos, I, McCarthy, J.G, Buchanan, S.K.
登録日2016-03-20
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.938 Å)
主引用文献Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
5IVA
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BU of 5iva by Molmil
The LPS Transporter LptDE from Pseudomonas aeruginosa, core complex
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LPS-assembly lipoprotein LptE, LPS-assembly protein LptD
著者Botos, I, Buchanan, S.K.
登録日2016-03-20
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.988 Å)
主引用文献Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
5IXM
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BU of 5ixm by Molmil
The LPS Transporter LptDE from Yersinia pestis, core complex
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LPS-assembly lipoprotein LptE, LPS-assembly protein LptD
著者Botos, I, Mayclin, S.J, McCarthy, J.G, Buchanan, S.K.
登録日2016-03-23
公開日2016-05-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.746 Å)
主引用文献Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
5IV9
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The LPS Transporter LptDE from Klebsiella pneumoniae, full-length
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LPS-assembly lipoprotein LptE, LPS-assembly protein LptD
著者Botos, I, McCarthy, J.G, Buchanan, S.K.
登録日2016-03-20
公開日2016-05-18
最終更新日2016-06-15
実験手法X-RAY DIFFRACTION (4.369 Å)
主引用文献Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens.
Structure, 24, 2016
1CXV
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BU of 1cxv by Molmil
STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)
分子名称: 2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE, CALCIUM ION, PROTEIN (COLLAGENASE-3), ...
著者Botos, I, Meyer, E, Swanson, S.M, Lemaitre, V, Eeckhout, Y, Meyer, E.F.
登録日1999-08-30
公開日2000-08-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of recombinant mouse collagenase-3 (MMP-13).
J.Mol.Biol., 292, 1999
1EQ9
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BU of 1eq9 by Molmil
CRYSTAL STRUCTURE OF FIRE ANT CHYMOTRYPSIN COMPLEXED TO PMSF
分子名称: CHYMOTRYPSIN, phenylmethanesulfonic acid
著者Botos, I, Meyer, E, Nguyen, M.H, Swanson, S.M, Meyer, E.F.
登録日2000-04-03
公開日2000-10-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structure of an insect chymotrypsin.
J.Mol.Biol., 298, 2000
1K6U
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BU of 1k6u by Molmil
Crystal Structure of Cyclic Bovine Pancreatic Trypsin Inhibitor
分子名称: 1,2-ETHANEDIOL, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION
著者Botos, I, Wu, Z, Lu, W, Wlodawer, A.
登録日2001-10-17
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor.
FEBS Lett., 509, 2001
1LOM
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CYANOVIRIN-N DOUBLE MUTANT P51S S52P
分子名称: CALCIUM ION, Cyanovirin-N, SULFATE ION
著者Botos, I, Mori, T, Cartner, L.K, Boyd, M.R, Wlodawer, A.
登録日2002-05-06
公開日2002-06-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Domain-swapped structure of a mutant of cyanovirin-N.
Biochem.Biophys.Res.Commun., 294, 2002
6N2I
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Lon protease AAA+ domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA-binding ATP-dependent protease La
著者Botos, I, Li, M, Wlodawer, A, Gustchina, A.
登録日2018-11-13
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献New insights into structural and functional relationships between LonA proteases and ClpB chaperones.
Febs Open Bio, 9, 2019
7UID
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BU of 7uid by Molmil
Thyclotides peptide nucleic acid in complex with DNA
分子名称: CHLORIDE ION, DNA (5'-D(*GP*AP*TP*GP*TP*GP*AP*TP*A)-3'), Thyclotide, ...
著者Botos, I, Appella, D.H.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids.
Jacs Au, 3, 2023
7KZL
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Cyclopentane peptide nucleic acid in complex with DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*TP*AP*TP*CP*AP*CP*AP*TP*C)-3'), IODIDE ION, ...
著者Botos, I, Appella, D.H.
登録日2020-12-10
公開日2020-12-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA.
Nucleic Acids Res., 49, 2021
3CIY
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Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R.
登録日2008-03-12
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
3CIG
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Crystal structure of mouse TLR3 ectodomain
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R.
登録日2008-03-11
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008

 

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