6VU4
 
 | | Structure of a beta-hairpin peptide mimic derived from Abeta 14-36 | | 分子名称: | Beta-hairpin Amyloid-beta precursor peptide mimic, CHLORIDE ION, IODIDE ION | | 著者 | Wierzbicki, M, Kreutzer, A, Samdin, T, Nowick, J.S. | | 登録日 | 2020-02-14 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.077 Å) | | 主引用文献 | Effects of N-Terminal Residues on the Assembly of Constrained beta-Hairpin Peptides Derived from A beta.
J.Am.Chem.Soc., 142, 2020
|
|
7JRH
 | |
7LIB
 | |
3P4J
 | | Ultra-high resolution structure of d(CGCGCG)2 Z-DNA | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE | | 著者 | Brzezinski, K, Brzuszkiewicz, A, Dauter, M, Kubicki, M, Jaskolski, M, Dauter, Z. | | 登録日 | 2010-10-06 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (0.55 Å) | | 主引用文献 | High regularity of Z-DNA revealed by ultra high-resolution crystal structure at 0.55 A.
Nucleic Acids Res., 39, 2011
|
|
2G7L
 | | Crystal structure of putative transcription regulator SCO7704 from Streptomyces coelicor | | 分子名称: | TetR-family transcriptional regulator | | 著者 | Ezersky, A, Lunin, V.V, Skarina, T, Wierzbicka, M, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2006-02-28 | | 公開日 | 2006-03-14 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of putative transcription regulator SCO7704 from Streptomyces coelicor
To be Published
|
|
6E00
 | | Structure of a N-Me-p-iodo-D-Phe1,N-Me-D-Gln4,Lys10-teixobactin analogue | | 分子名称: | N-Me-p-iodo-D-Phe1,N-Me-D-Gln4,Lys10-teixobactin analogue, SULFATE ION | | 著者 | Nowick, J.S, Yang, H, Wierzbicki, M. | | 登録日 | 2018-07-05 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-like Assembly.
J. Am. Chem. Soc., 140, 2018
|
|
6XMX
 | | Cryo-EM structure of BCL6 bound to BI-3802 | | 分子名称: | 2-[6-[[5-chloranyl-2-[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxidanylidene-quinolin-3-yl]oxy-~{N}-methyl-ethanamide, B-cell lymphoma 6 protein | | 著者 | Yoon, H, Burman, S.S.R, Hunkeler, M, Nowak, R.P, Fischer, E.S. | | 登録日 | 2020-07-01 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Small-molecule-induced polymerization triggers degradation of BCL6.
Nature, 588, 2020
|
|
6TD3
 | | Structure of DDB1 bound to CR8-engaged CDK12-cyclinK | | 分子名称: | (2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... | | 著者 | Bunker, R.D, Petzold, G, Kozicka, Z, Thoma, N.H. | | 登録日 | 2019-11-07 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K.
Nature, 585, 2020
|
|
7KXS
 | | Computational design of constitutively active cGAS | | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | | 著者 | Dowling, Q, Volkman, H.E, Gray, E.E, Ovchinnikov, S, Cambier, S, Bera, A.K, Bick, M, Kang, A, Stetson, D.B, King, N.P. | | 登録日 | 2020-12-04 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Computational design of constitutively active cGAS.
Nat.Struct.Mol.Biol., 30, 2023
|
|
7LZ3
 | | Computational design of constitutively active cGAS | | 分子名称: | Cyclic GMP-AMP synthase, GLYCEROL, ZINC ION | | 著者 | Dowling, Q, Volkman, H.E, Gray, E.E, Ovchinnikov, S, Cambier, S, Bera, A.K, Bick, M, Kang, A, Stetson, D.B, King, N.P. | | 登録日 | 2021-03-08 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Computational design of constitutively active cGAS.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8GBX
 | |
8GBY
 | | Crystal structure of PC39-50E, an anti-HIV broadly neutralizing antibody | | 分子名称: | GLYCEROL, PC39-50E Fab heavy chain, PC39-50E Fab light chain | | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
|
|
8GBW
 | | Crystal structure of PC39-23D, an anti-HIV broadly neutralizing antibody | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PC39-23D Fab heavy chain, ... | | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
|
|
8GC0
 | | Crystal structure of PC39-50L, an anti-HIV broadly neutralizing antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PC39-50L Fab heavy chain, PC39-50L Fab light chain | | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
|
|
8GBV
 | | Crystal structure of PC39-17A, an anti-HIV broadly neutralizing antibody | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PC39-17A Fab heavy chain, ... | | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
|
|
8GC1
 | |
8GBZ
 | | Crystal structure of PC39-55C, an anti-HIV broadly neutralizing antibody | | 分子名称: | DI(HYDROXYETHYL)ETHER, PC39-55C Fab heavy chain, PC39-55C Fab light chain | | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
|
|
5JZQ
 | |
4R15
 | | High-resolution crystal structure of Z-DNA in complex with Cr3+ cations | | 分子名称: | CHROMIUM ION, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3') | | 著者 | Drozdzal, P, Gilski, M, Kierzek, R, Lomozik, L, Jaskolski, M. | | 登録日 | 2014-08-04 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | High-resolution crystal structure of Z-DNA in complex with Cr(3+) cations.
J.Biol.Inorg.Chem., 20, 2015
|
|
9B9R
 | |
9B9V
 | |
5EBI
 | | Crystal structure of a DNA-RNA chimera in complex with Ba2+ ions: a case of unusual multi-domain twinning | | 分子名称: | BARIUM ION, DNA/RNA (5'-D(*C)-R(P*G)-D(P*C)-R(P*G)-D(P*C)-R(P*G)-3') | | 著者 | Gilski, M, Drozdzal, P, Kierzek, R, Jaskolski, M. | | 登録日 | 2015-10-19 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Atomic resolution structure of a chimeric DNA-RNA Z-type duplex in complex with Ba(2+) ions: a case of complicated multi-domain twinning.
Acta Crystallogr D Struct Biol, 72, 2016
|
|
8G46
 | | Cryo-EM structure of DDB1deltaB-DDA1-DCAF16-BRD4(BD2)-MMH2 | | 分子名称: | Bromodomain-containing protein 4, DDB1- and CUL4-associated factor 16, DET1- and DDB1-associated protein 1, ... | | 著者 | Ma, M.W, Hunkeler, M, Jin, C.Y, Fischer, E.S. | | 登録日 | 2023-02-08 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders.
Biorxiv, 2023
|
|
4HIG
 | | Ultrahigh-resolution crystal structure of Z-DNA in complex with Mn2+ ion. | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MANGANESE (II) ION, SPERMINE (FULLY PROTONATED FORM) | | 著者 | Drozdzal, P, Gilski, M, Kierzek, R, Lomozik, L, Jaskolski, M. | | 登録日 | 2012-10-11 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (0.75 Å) | | 主引用文献 | Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ions.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4HIF
 | | Ultrahigh-resolution crystal structure of Z-DNA in complex with Zn2+ ions | | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE (FULLY PROTONATED FORM), ... | | 著者 | Drozdzal, P, Gilski, M, Kierzek, R, Lomozik, L, Jaskolski, M. | | 登録日 | 2012-10-11 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ions.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
