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8TE7
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BU of 8te7 by Molmil
Structure of TRNM-f.01
分子名称: TRNM-f.01 Fab Heavy Chain, TRNM-f.01 Fab Light Chain
著者Bender, M.F, Olia, A.S, Kwong, P.D.
登録日2023-07-05
公開日2024-07-10
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Broad and Potent HIV-1 Neutralization in Fusion Peptide-primed SHIV-boosted Macaques
To Be Published
5IQ9
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BU of 5iq9 by Molmil
Crystal structure of 10E8v4 Fab in complex with an HIV-1 gp41 peptide.
分子名称: 10E8v4 Heavy Chain, 10E8v4 Light Chain, gp41 MPER peptide
著者Ofek, G, Kwon, Y.D, Caruso, W, Kwong, P.D.
登録日2016-03-10
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
J.Virol., 90, 2016
8FIS
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BU of 8fis by Molmil
Structure of Bispecific CAP256V2LS-J3 Fab in complex with BG505 DS-SOSIP.664
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者Gorman, J, Kwong, P.D.
登録日2022-12-16
公開日2023-02-01
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.
Mabs, 15, 2023
7TZ0
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BU of 7tz0 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin (Local refinement of FSR22 and RBD)
分子名称: DARPin FSR22, Spike glycoprotein
著者Kwon, Y.D, Gorman, J, Kwong, P.D.
登録日2022-02-15
公開日2022-12-07
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
7TYZ
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BU of 7tyz by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DARPin FSR22, ...
著者Kwon, Y.D, Gorman, J, Kwong, P.D.
登録日2022-02-15
公開日2022-12-07
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
8DW2
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BU of 8dw2 by Molmil
Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR22, and two antibody Fabs, S309 and CR3022
分子名称: Antibody CR3022 heavy chain, Antibody CR3022 light chain, Antibody S309 heavy chain, ...
著者Kwon, Y.D, Gorman, J, Kwong, P.D.
登録日2022-07-30
公開日2022-12-07
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (4.11 Å)
主引用文献A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
8DW3
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BU of 8dw3 by Molmil
Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR16m, and two antibody Fabs, S309 and CR3022
分子名称: Anti-SARS-CoV-2 DARPin SR16m, Antibody S309 light chain, Spike protein S1, ...
著者Kwon, Y.D, Gorman, J, Kwong, P.D.
登録日2022-07-30
公開日2022-12-07
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (4.26 Å)
主引用文献A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
8EK1
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BU of 8ek1 by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(dominant class)
分子名称: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
著者Tripathi, P, Kwong, P.D.
登録日2022-09-19
公開日2023-03-15
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
8EKA
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BU of 8eka by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(class 2)
分子名称: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
著者Tripathi, P, Kwong, P.D.
登録日2022-09-20
公開日2023-03-15
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023
5IQ7
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BU of 5iq7 by Molmil
Crystal structure of 10E8-S74W Fab in complex with an HIV-1 gp41 peptide.
分子名称: 10E8-S74W Heavy Chain, 10E8-S74W Light Chain, gp41 MPER peptide
著者Ofek, G, Kwon, Y.D, Caruso, W, Kwong, P.D.
登録日2016-03-10
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2869 Å)
主引用文献Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
J.Virol., 90, 2016
7MFB
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BU of 7mfb by Molmil
Crystal structure of antibody 10E8v4 Fab - light chain H31F variant
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MFA
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BU of 7mfa by Molmil
Crystal structure of antibody 10E8v4-P100fA+P100gA Fab
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF7
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BU of 7mf7 by Molmil
Crystal structure of antibody 10E8v4-P100gA Fab
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF9
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BU of 7mf9 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group C2
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF8
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BU of 7mf8 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group P6422
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021

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件を2024-09-11に公開中

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