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2RDG
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Crystal structure of Staphylococcal Superantigen-Like protein 11 in complex with Sialyl Lewis X
分子名称: CITRIC ACID, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, POTASSIUM ION, ...
著者Chung, M.C, Wines, B.D, Baker, H, Langley, R.J, Baker, E.N, Fraser, J.D.
登録日2007-09-24
公開日2007-12-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition
Mol.Microbiol., 66, 2007
2RDH
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BU of 2rdh by Molmil
Crystal structure of Staphylococcal Superantigen-Like protein 11
分子名称: PHOSPHATE ION, SODIUM ION, Superantigen-like protein 11
著者Chung, M.C, Wines, B.D, Baker, H, Langley, R.J, Baker, E.N, Fraser, J.D.
登録日2007-09-24
公開日2007-12-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition
Mol.Microbiol., 66, 2007
1A8E
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BU of 1a8e by Molmil
HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
分子名称: CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN
著者Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N.
登録日1998-03-24
公開日1998-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
1A8F
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BU of 1a8f by Molmil
HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
分子名称: CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN
著者Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N.
登録日1998-03-25
公開日1998-06-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
5U75
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BU of 5u75 by Molmil
The structure of Staphylococcal Enterotoxin-like X (SElX), a Unique Superantigen
分子名称: Enterotoxin-like toxin X, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose
著者Ting, Y.T, Young, P.G, Langley, R.J, Baker, H, Fraser, J.D.
登録日2016-12-11
公開日2017-08-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Staphylococcal enterotoxin-like X (SElX) is a unique superantigen with functional features of two major families of staphylococcal virulence factors.
PLoS Pathog., 13, 2017
9CKV
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BU of 9ckv by Molmil
Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Werther, R, Nguyen, A, Estrada Alamo, K.A, Wang, X, Campbell, M.G.
登録日2024-07-09
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献De Novo Design of Integrin alpha5beta1 Modulating Proteins for Regenerative Medicine
To Be Published
7S5B
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BU of 7s5b by Molmil
Unbound State of a De novo designed Protein Binder to the Human Interleukin-7 Receptor
分子名称: Miniprotein Binder
著者Walsh, S.T.R, Cao, L, Baker, D.
登録日2021-09-10
公開日2022-05-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
5WP3
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Crystal Structure of EED in complex with EB22
分子名称: EB22, Polycomb protein EED, UNKNOWN ATOM OR ION
著者Dong, C, Tempel, W, Zhu, L, Moody, J.D, Baker, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-08-03
公開日2017-09-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7UHB
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BU of 7uhb by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, Spike glycoprotein
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-03-26
公開日2022-06-08
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
7UHC
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BU of 7uhc by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-03-26
公開日2022-06-08
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
7RDH
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BU of 7rdh by Molmil
Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ...
著者Kadam, R.U, Wilson, I.A.
登録日2021-07-09
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7OPB
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BU of 7opb by Molmil
IL7R in complex with an antagonist
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ...
著者Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N.
登録日2021-05-31
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1J
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BU of 7n1j by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
分子名称: Binder, Fibroblast growth factor receptor 4
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1K
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BU of 7n1k by Molmil
Crystal structure of a de novo-designed mini-protein targeting FGFR
分子名称: Binder
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N3T
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BU of 7n3t by Molmil
TrkA ECD complex with designed miniprotein ligand
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jude, K.M, Cao, L, Garcia, K.C.
登録日2021-06-01
公開日2022-04-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
8F6R
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BU of 8f6r by Molmil
CryoEM structure of designed modular protein oligomer C6-79
分子名称: De novo designed oligomeric protein C6-79
著者Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G.
登録日2022-11-17
公開日2023-11-29
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Cell, 187, 2024
8F6Q
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BU of 8f6q by Molmil
CryoEM structure of designed modular protein oligomer C8-71
分子名称: C8-71
著者Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G.
登録日2022-11-17
公開日2023-11-29
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Cell, 187, 2024
8F54
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BU of 8f54 by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_1
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F4X
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BU of 8f4x by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_1-H11
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F53
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Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_2
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
7Z7P
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BU of 7z7p by Molmil
Structure of the fluorescent protein NeonCyan0.95 at pH 5.6
分子名称: NeonCyan0.95, SULFATE ION
著者Depernet, H, Dupuy, J, Royant, A.
登録日2022-03-16
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Cyan fluorescent proteins derived from mNeonGreen.
Protein Eng.Des.Sel., 35, 2022
7Z7Q
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Structure of the T207D single-point mutant of the fluorescent protein NeonCyan1 at pH 6.5
分子名称: NeonCyan1
著者Duarte, K, Dupuy, J, Royant, A.
登録日2022-03-16
公開日2022-05-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cyan fluorescent proteins derived from mNeonGreen.
Protein Eng.Des.Sel., 35, 2022
7Z7O
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Structure of the fluorescent protein NeonCyan0.95 at pH 7.5
分子名称: NeonCyan0.95
著者Clavel, D, Dupuy, J, Royant, A.
登録日2022-03-16
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Cyan fluorescent proteins derived from mNeonGreen.
Protein Eng.Des.Sel., 35, 2022

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