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4HBC
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Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers
分子名称: Antigen Binding Fragment, Immunoglobulin IgG - Heavy Chain, Immunoglobulin IgG - Light Chain, ...
著者Arai, H.
登録日2012-09-27
公開日2012-10-31
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers.
Biochim.Biophys.Acta, 1820, 2012
1WAB
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BU of 1wab by Molmil
PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
分子名称: ACETATE ION, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
著者Ho, Y.S, Swenson, L, Derewenda, U, Serre, L, Wei, Y, Dauter, Z, Hattori, M, Aoki, J, Arai, H, Adachi, T, Inoue, K, Derewenda, Z.S.
登録日1996-10-30
公開日1997-11-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer.
Nature, 385, 1997
2NAO
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BU of 2nao by Molmil
Atomic resolution structure of a disease-relevant Abeta(1-42) amyloid fibril
分子名称: Beta-amyloid protein 42
著者Waelti, M.A, Ravotti, F, Arai, H, Glabe, C, Wall, J, Bockmann, A, Guntert, P, Meier, B.H, Riek, R.
登録日2016-01-07
公開日2016-07-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Atomic-resolution structure of a disease-relevant A beta (1-42) amyloid fibril.
Proc.Natl.Acad.Sci.USA, 113, 2016
1BWQ
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
分子名称: PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
著者Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z.
登録日1998-09-27
公開日1999-05-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWP
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
分子名称: PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
著者Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z.
登録日1998-09-27
公開日1999-05-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWR
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BU of 1bwr by Molmil
PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
分子名称: PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
著者Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z.
登録日1998-09-27
公開日1999-05-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1ES9
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BU of 1es9 by Molmil
X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH)
分子名称: PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT
著者McMullen, T.W.P, Li, J, Sheffield, P.J, Aoki, J, Martin, T.W, Arai, H, Inoue, K, Derewenda, Z.S.
登録日2000-04-07
公開日2000-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib).
Protein Eng., 13, 2000
4IJ6
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BU of 4ij6 by Molmil
Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from Hydrogenobacter thermophilus TK-6 in Complex with L-phosphoserine
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHOSERINE, ...
著者Chiba, Y, Horita, S, Ohtsuka, J, Arai, H, Nagata, K, Igarashi, Y, Tanokura, M, Ishii, M.
登録日2012-12-21
公開日2013-03-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural units important for activity of a novel-type phosphoserine phosphatase from Hydrogenobacter thermophilus TK-6 revealed by crystal structure analysis
J.Biol.Chem., 288, 2013
4IJ5
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Crystal Structure of a Novel-type Phosphoserine Phosphatase from Hydrogenobacter thermophilus TK-6
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Phosphoserine phosphatase 1
著者Chiba, Y, Horita, S, Ohtsuka, J, Arai, H, Nagata, K, Igarashi, Y, Tanokura, M, Ishii, M.
登録日2012-12-21
公開日2013-03-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural units important for activity of a novel-type phosphoserine phosphatase from Hydrogenobacter thermophilus TK-6 revealed by crystal structure analysis
J.Biol.Chem., 288, 2013
1JFR
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CRYSTAL STRUCTURE OF THE STREPTOMYCES EXFOLIATUS LIPASE AT 1.9A RESOLUTION: A MODEL FOR A FAMILY OF PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES
分子名称: LIPASE
著者Wei, Y, Derewenda, Z.S.
登録日1997-07-11
公開日1998-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution.
Structure, 6, 1998
5EGE
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BU of 5ege by Molmil
Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J.
登録日2015-10-27
公開日2016-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Sci Rep, 6, 2016
5EGH
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BU of 5egh by Molmil
Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J.
登録日2015-10-27
公開日2016-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Sci Rep, 6, 2016
5GUX
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BU of 5gux by Molmil
Cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with xenon
分子名称: Antibody fab fragment heavy chain, Antibody fab fragment light chain, CALCIUM ION, ...
著者Ishii, S, Terasaka, E, Sugimoto, H, Shiro, Y, Tosha, T.
登録日2016-08-31
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Dynamics of nitric oxide controlled by protein complex in bacterial system.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5GUW
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BU of 5guw by Molmil
Complex of Cytochrome cd1 Nitrite Reductase and Nitric Oxide Reductase in Denitrification of Pseudomonas aeruginosa
分子名称: CALCIUM ION, CHLORIDE ION, FE (III) ION, ...
著者Terasaka, E, Sugimoto, H, Shiro, Y, Tosha, T.
登録日2016-08-31
公開日2017-08-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Dynamics of nitric oxide controlled by protein complex in bacterial system
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3VIA
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BU of 3via by Molmil
Crystal structure of the PH domain of Evectin-2 from human
分子名称: Pleckstrin homology domain-containing family B member 2
著者Okazaki, S, Kato, R, Wakatsuki, S.
登録日2011-09-26
公開日2012-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis of the strict phospholipid binding specificity of the pleckstrin homology domain of human evectin-2
Acta Crystallogr.,Sect.D, 68, 2012
4CH7
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BU of 4ch7 by Molmil
Crystal structure of the siroheme decarboxylase NirDL
分子名称: NIRD-LIKE PROTEIN
著者Schmelz, S, Kriegler, T.M, Haufschildt, K, Layer, G, Heinz, D.W.
登録日2013-11-29
公開日2014-07-30
最終更新日2014-09-10
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献The Crystal Structure of Siroheme Decarboxylase in Complex with Iron-Uroporphyrin III Reveals Two Essential Histidine Residues
J.Mol.Biol., 426, 2014
4CZC
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BU of 4czc by Molmil
Crystal structure of the siroheme decarboxylase NirDL in co-complex with iron-uroporphyrin III analogue
分子名称: Fe(III) Uroporphyrin, NIRD-LIKE PROTEIN
著者Schmelz, S, Kriegler, T.M, Haufschildt, K, Layer, G, Heinz, D.W.
登録日2014-04-17
公開日2014-07-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Crystal Structure of Siroheme Decarboxylase in Complex with Iron-Uroporphyrin III Reveals Two Essential Histidine Residues
J.Mol.Biol., 426, 2014
3DT9
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BU of 3dt9 by Molmil
Crystal Structure of Bovin Brain Platelet Activating Factor Acetylhydrolase Covalently Inhibited by Soman
分子名称: (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE, Brain Platelet-activating factor acetylhydrolase IB subunit alpha
著者Epstein, T.M, Samanta, U, Bahnson, B.J.
登録日2008-07-14
公開日2009-05-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Biochemistry, 48, 2009
3DT8
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Crystal Structure of Bovin Brain Platelet Activating Factor Acetylhydrolase Covalently Inhibited by Sarin
分子名称: Brain Platelet-activating factor acetylhydrolase IB subunit alpha
著者Epstein, T.M, Samanta, U, Bahnson, B.J.
登録日2008-07-14
公開日2009-05-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Biochemistry, 48, 2009
3DT6
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Crystal Structure of Bovin Brain Platelet Activating Factor Acetylhydrolase Covalently Inhibited by Paraoxon
分子名称: Brain Platelet-activating factor acetylhydrolase IB subunit alpha, DIETHYL PHOSPHONATE
著者Epstein, T.M, Samanta, U, Bahnson, B.J.
登録日2008-07-14
公開日2009-05-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Biochemistry, 48, 2009
3W67
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Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(3,4)-bisphosphate
分子名称: (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Alpha-tocopherol transfer protein
著者Ohto, U, Satow, Y.
登録日2013-02-11
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Impaired alpha-TTP-PIPs interaction underlies familial vitamin E deficiency
Science, 340, 2013
3W68
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Crystal structure of mouse alpha-tocopherol transfer protein in complex with alpha-tocopherol and phosphatidylinositol-(4,5)-bisphosphate
分子名称: (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, ...
著者Ohto, U, Satow, Y.
登録日2013-02-11
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Impaired alpha-TTP-PIPs interaction underlies familial vitamin E deficiency
Science, 340, 2013
3AJ4
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BU of 3aj4 by Molmil
Crystal structure of the PH domain of Evectin-2 from human complexed with O-phospho-L-serine
分子名称: 1,2-ETHANEDIOL, PHOSPHOSERINE, Pleckstrin homology domain-containing family B member 2
著者Okazaki, S, Kato, R, Wakatsuki, S.
登録日2010-05-21
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes
Proc.Natl.Acad.Sci.USA, 108, 2011
1FXW
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BU of 1fxw by Molmil
CRYSTAL STRUCTURE OF THE RECOMBINANT ALPHA1/ALPHA2 CATALYTIC HETERODIMER OF BOVINE BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB.
分子名称: CALCIUM ION, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT
著者Derewenda, Z, Li, J.
登録日2000-09-27
公開日2001-12-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Preparation and crystal structure of the recombinant alpha(1)/alpha(2) catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib.
Protein Eng., 14, 2001
1V7M
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BU of 1v7m by Molmil
Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab
分子名称: Monoclonal TN1 Fab Heavy Chain, Monoclonal TN1 Fab Light Chain, Thrombopoietin
著者Feese, M.D, Tamada, T, Kato, Y, Maeda, Y, Hirose, M, Matsukura, Y, Shigematsu, H, Kato, T, Miyazaki, H, Kuroki, R.
登録日2003-12-18
公開日2004-03-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
Proc.Natl.Acad.Sci.USA, 101, 2004

 

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