8B69
 
 | | Heterotetramer of K-Ras4B(G12V) and Rgl2(RBD) | | 分子名称: | Isoform 2B of GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Tariq, M, Fairall, L, Romartinez-Alonso, B, Dominguez, C, Schwabe, J.W.R, Tanaka, K. | | 登録日 | 2022-09-26 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator.
Life Sci Alliance, 7, 2024
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2HZK
 | | Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its open form | | 分子名称: | GLYCEROL, TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, ... | | 著者 | Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D. | | 登録日 | 2006-08-09 | | 公開日 | 2007-04-03 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding.
Bmc Struct.Biol., 7, 2007
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2HZL
 | | Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its closed forms | | 分子名称: | PYRUVIC ACID, SODIUM ION, TRAP-T family sorbitol/mannitol transporter, ... | | 著者 | Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D. | | 登録日 | 2006-08-09 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding.
Bmc Struct.Biol., 7, 2007
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8P0D
 | | Human 14-3-3 sigma in complex with human MDM2 peptide | | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Roversi, P, Ward, J, Doveston, R, Kwon, H, Romartinez Alonso, B. | | 登録日 | 2023-05-10 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Characterizing the protein-protein interaction between MDM2 and 14-3-3 sigma ; proof of concept for small molecule stabilization.
J.Biol.Chem., 300, 2024
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7QDT
 | | Crystal structure of a mutant (P393GX) Thyroid Receptor Alpha ligand binding domain designed to model dominant negative human mutations. | | 分子名称: | 3,5,3'TRIIODOTHYRONINE, Isoform Alpha-1 of Thyroid hormone receptor alpha | | 著者 | Romartinez-Alonso, B, Fairall, L, Agostini, M, Chatterjee, K, Schwabe, J. | | 登録日 | 2021-11-30 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone alpha.
Mol.Cell.Biol., 42, 2022
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7AZN
 | | Structure of mouse AsterC (GramD1c) with a new cholesterol-derived compound | | 分子名称: | 20alpha-hydroxy-20-(5-methylhexyl)cholesterol, ETHANOL, GLYCEROL, ... | | 著者 | Romartinez-Alonso, B, Sirvydis, K, Kim, Y, Xiao, X, Jung, M, Tontonoz, P, Schwabe, J. | | 登録日 | 2020-11-16 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8AU4
 | | Structural insights reveal a heterotetramer between oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator | | 分子名称: | Ral guanine nucleotide dissociation stimulator-like 2 | | 著者 | Tariq, M, Ikeya, T, Togashi, N, Fairall, L, Alejo, C.B, Kamei, S, Alonso, B.R, Campillo, M.A.M, Hudson, A, Ito, Y, Schwabe, J, Dominguez, C, Tanaka, K. | | 登録日 | 2022-08-25 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator.
Life Sci Alliance, 7, 2024
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8AXW
 | | The structure of mouse AsterC (GramD1c) with Ezetimibe | | 分子名称: | (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, CHLORIDE ION, ETHANOL, ... | | 著者 | Fairall, L, Xiao, X, Burger, L, Tontonoz, P, Schwabe, J.W.R. | | 登録日 | 2022-09-01 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Science, 382, 2023
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