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4PUF
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BU of 4puf by Molmil
Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1
分子名称: E3 ubiquitin-protein ligase SlrP, Thioredoxin
著者Zouhir, S, Bernal-Bayard, J, Cordero-Alba, M, Cardenal-Munoz, E, Guimaraes, B, Lazar, N, Ramos-Morales, F, Nessler, S.
登録日2014-03-13
公開日2014-09-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.296 Å)
主引用文献The structure of the Slrp-Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family.
Biochem.J., 464, 2014
1SM7
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BU of 1sm7 by Molmil
Solution structure of the recombinant pronapin precursor, BnIb.
分子名称: recombinant Ib pronapin
著者Pantoja-Uceda, D, Palomares, O, Bruix, M, Villalba, M, Rodriguez, R, Rico, M, Santoro, J.
登録日2004-03-08
公開日2005-02-01
最終更新日2013-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and stability against digestion of rproBnIb, a recombinant 2S albumin from rapeseed: relationship to its allergenic properties.
Biochemistry, 43, 2004
1SS3
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BU of 1ss3 by Molmil
Solution structure of Ole e 6, an allergen from olive tree pollen
分子名称: Pollen allergen Ole e 6
著者Trevino, M.A, Garcia-Mayoral, M.F, Barral, P, Villalba, M, Santoro, J, Rico, M, Rodriguez, R, Bruix, M.
登録日2004-03-23
公開日2004-08-03
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of Ole e 6, a Major Allergen from Olive Tree Pollen.
J.Biol.Chem., 279, 2004
4KNB
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BU of 4knb by Molmil
C-Met in complex with OSI ligand
分子名称: 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor
著者Wang, J, Steinig, A.G, Li, A.H, Chen, X, Dong, H, Ferraro, C, Jin, M, Kadalbajoo, M, Kleinberg, A, Stolz, K.M, Tavares-Greco, P.A, Wang, T, Albertella, M.R, Peng, Y, Crew, L, Kahler, J.
登録日2013-05-09
公開日2014-04-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg.Med.Chem.Lett., 23, 2013
4ID7
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BU of 4id7 by Molmil
ACK1 kinase in complex with the inhibitor cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol
分子名称: Activated CDC42 kinase 1, SULFATE ION, cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol
著者Jin, M, Wang, J, Kleinberg, A, Kadalbajoo, M, Siu, K, Cooke, A, Bittner, M, Yao, Y, Thelemann, A, Ji, Q, Bhagwat, S, Crew, A.P, Pachter, J, Epstein, D, Mulvihill, M.J.
登録日2012-12-11
公開日2013-01-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
6YOA
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BU of 6yoa by Molmil
Lig v 1 structure and the inflammatory response to the Ole e 1 protein family
分子名称: Major pollen allergen Lig v 1, NICKEL (II) ION
著者Robledo-Retana, T, Bradley-Clark, J, Croll, T, Rose, R, Stagg, A, Villalba, M, Pickersgill, R.
登録日2020-04-14
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Lig v 1 structure and the inflammatory response to the Ole e 1 protein family.
Allergy, 75, 2020
2JON
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BU of 2jon by Molmil
Solution structure of the C-terminal domain Ole e 9
分子名称: Beta-1,3-glucanase
著者Trevino, M.A, Palomares, O, Castrillo, I, Villalba, M, Rodriguez, R, Rico, M, Santoro, J, Bruix, M.
登録日2007-03-14
公開日2008-01-29
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal domain of Ole e 9, a major allergen of olive pollen
Protein Sci., 17, 2008
2MUJ
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BU of 2muj by Molmil
Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria
分子名称: Serine-repeat antigen protein
著者Cubillos, M, Alba, M, Bermudez, A, Trujillo, M, Patarroyo, M.E.
登録日2014-09-10
公開日2015-02-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria.
Biochimie, 85, 2003
2MUD
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BU of 2mud by Molmil
Structural modifications to a high-activity binding peptide located whitin the PfEMP1 NTS domain induce protection against P. falciparum malaria in Aotus monkeys
分子名称: Variant-specific surface protein
著者Curtidor, H, Torres, M, Alba, M, Patarroyo, M.
登録日2014-09-08
公開日2015-09-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural modifications to a high-activity binding peptide located within the PfEMP1 NTS domain induce protection against P. falciparum malaria in Aotus monkeys.
Biol.Chem., 388, 2007
2MU9
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BU of 2mu9 by Molmil
Changing ABRA protein peptide to fit the HLA-DR B1*0301 molecule renders it protection-inducing
分子名称: P101/acidic basic repeat antigen
著者Salazar, L, Alba, M, Curtidor, H, Bermudez, A, Vargas, L, Rivera, Z, Patarroyo, M.
登録日2014-09-04
公開日2015-09-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Changing ABRA protein peptide to fit into the HLA-DRbeta1*0301 molecule renders it protection-inducing.
Biochem.Biophys.Res.Commun., 322, 2004
7OVD
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BU of 7ovd by Molmil
Human soluble adenylyl cyclase in complex with the inhibitor TDI10229
分子名称: 1,2-ETHANEDIOL, 4-chloranyl-6-[1,5-dimethyl-4-(phenylmethyl)pyrazol-3-yl]pyrimidin-2-amine, ACETATE ION, ...
著者Steegborn, C, Quast, J.
登録日2021-06-14
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).
Acs Med.Chem.Lett., 12, 2021
9EP9
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BU of 9ep9 by Molmil
NMR solution structure of lipid transfer protei Sola l7 from tomato seeds
分子名称: Non-specific lipid-transfer protein
著者Parron-Ballesteros, J, Mantin-Pedraz, L, G.Gordo, R, Mayorga, C, Villaba, M, Batanero, E, Pantoja-Uceda, D, Turnay, J.
登録日2024-03-18
公開日2024-09-04
実験手法SOLUTION NMR
主引用文献Long-chain fatty acids block allergic reaction against lipid transfer protein Sola l 7 from tomato seeds.
Protein Sci., 33, 2024
2OPO
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BU of 2opo by Molmil
Crystal structure of the calcium-binding pollen allergen Che a 3
分子名称: CALCIUM ION, Polcalcin Che a 3, SULFATE ION
著者Verdino, P, Keller, W.
登録日2007-01-29
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Three-dimensional structure of the cross-reactive pollen allergen Che a 3: visualizing cross-reactivity on the molecular surfaces of weed, grass, and tree pollen allergens.
J.Immunol., 180, 2008
8B75
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BU of 8b75 by Molmil
CRYSTAL STRUCTURE OF HUMAN SOLUBLE ADENYLYL CYCLASE IN COMPLEX WITH THE INHIBITOR TDI-011861
分子名称: Adenylate cyclase type 10, [(3~{R})-4-[2-[2-[[3-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-1-[bis(fluoranyl)methyl]pyrazol-4-yl]methyl]phenoxy]ethyl]morpholin-3-yl]methanol
著者Steegborn, C, Kehr, M.
登録日2022-09-28
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.
J.Med.Chem., 65, 2022
6XEQ
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BU of 6xeq by Molmil
Crystal structure of the tetrameric 6-phosphogluconate dehydrogenase from Gluconobacter oxidans
分子名称: 6-phosphogluconate dehydrogenase, SULFATE ION
著者Maturana, P, Roversi, P, Castro-Fernandez, V, Herrera-Morande, A, Garratt, R.C, Cabrera, R.
登録日2020-06-13
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 6-phosphogluconate dehydrogenase from Gluconobacter oxydans reveals tetrameric 6PGDHs as the crucial intermediate in the evolution of structure and cofactor preference in the 6PGDH family [version 1; peer review: 1 approved, 1 approved with reservations]
Wellcome Open Res, 6, 2021
5JX4
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BU of 5jx4 by Molmil
Crystal structure of E36-G37del mutant of the Bacillus caldolyticus cold shock protein.
分子名称: Cold shock protein CspB, SULFATE ION
著者Carvajal, A, Castro-Fernandez, V, Cabrejos, D, Fuentealba, M, Pereira, H.M, Vallejos, G, Cabrera, R, Garratt, R.C, Komives, E.A, Ramirez-Sarmiento, C.A, Babul, J.
登録日2016-05-12
公開日2017-05-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Unusual dimerization of a BcCsp mutant leads to reduced conformational dynamics.
FEBS J., 284, 2017
4Z8W
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BU of 4z8w by Molmil
Crystal Structure of the Major Plantain Pollen Allergen Pla l 1
分子名称: Major pollen allergen Pla l 1, ZINC ION
著者Freier, R, Brandstetter, H.
登録日2015-04-09
公開日2016-07-06
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family.
J. Allergy Clin. Immunol., 140, 2017
8PF2
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BU of 8pf2 by Molmil
Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK16
分子名称: Chemotaxis protein CheA, RESORCINOL
著者Adhav, A, Marina, A.
登録日2023-06-15
公開日2024-06-26
最終更新日2024-08-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Repurposing Hsp90 inhibitors as antimicrobials targeting two-component systems identifies compounds leading to loss of bacterial membrane integrity.
Microbiol Spectr, 12, 2024
6C8Z
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BU of 6c8z by Molmil
Last common ancestor of ADP-dependent phosphofructokinases from Methanosarcinales
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADP-dependent phosphofructokinase, MAGNESIUM ION, ...
著者Castro-Fernandez, V, Gonzalez-Ordenes, F, Munoz, S, Fuentes, N, Leonardo, D, Fuentealba, M, Herrera-Morande, A, Maturana, P, Villalobos, P, Garratt, R.
登録日2018-01-25
公開日2018-02-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献ADP-Dependent Kinases From the Archaeal OrderMethanosarcinalesAdapt to Salt by a Non-canonical Evolutionarily Conserved Strategy.
Front Microbiol, 9, 2018

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