5HWS
 
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5AYV
 | | Crystal structure of archaeal ketopantoate reductase complexed with coenzyme A and 2-oxopantoate | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-dehydropantoate 2-reductase, ACETATE ION, ... | | 著者 | Aikawa, Y, Nishitani, Y, Miki, K. | | 登録日 | 2015-09-08 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.647 Å) | | 主引用文献 | Crystal structure of archaeal ketopantoate reductase complexed with coenzyme a and 2-oxopantoate provides structural insights into feedback regulation
Proteins, 84, 2016
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6KX8
 | | Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound | | 分子名称: | 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2 | | 著者 | Miller, S.A, Aikawa, Y, Hirota, T. | | 登録日 | 2019-09-10 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
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6KX7
 | | Crystal structure of mouse Cryptochrome 1 in complex with TH301 compound | | 分子名称: | 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-1 | | 著者 | Miller, S.A, Aikawa, Y, Hirota, T. | | 登録日 | 2019-09-10 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
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6KX5
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6KX6
 | | Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound | | 分子名称: | Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide | | 著者 | Miller, S.A, Aikawa, Y, Hirota, T. | | 登録日 | 2019-09-10 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
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6KX4
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6LUE
 | | Crystal structure of mouse Cryptochrome 1 in complex with compound KL201 | | 分子名称: | 2-bromanyl-N-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)benzamide, Cryptochrome-1 | | 著者 | Miller, S, Aikawa, Y, Hirota, T. | | 登録日 | 2020-01-27 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals.
Cell Chem Biol, 27, 2020
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7D0N
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7DLI
 | | Crystal structure of mouse CRY1 in complex with KL001 compound | | 分子名称: | 1,2-ETHANEDIOL, Cryptochrome-1, N-[(2R)-3-carbazol-9-yl-2-oxidanyl-propyl]-N-(furan-2-ylmethyl)methanesulfonamide | | 著者 | Miller, S.A, Aikawa, Y, Hirota, T. | | 登録日 | 2020-11-27 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7D0M
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3W1Z
 | | Heat shock protein 16.0 from Schizosaccharomyces pombe | | 分子名称: | Heat shock protein 16 | | 著者 | Hanazono, Y, Takeda, K, Akiyama, N, Aikawa, Y, Miki, K. | | 登録日 | 2012-11-26 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Nonequivalence Observed for the 16-Meric Structure of a Small Heat Shock Protein, SpHsp16.0, from Schizosaccharomyces pombe
Structure, 21, 2013
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6A1C
 | | Crystal structure of the CK2a1-go289 complex | | 分子名称: | 1,2-ETHANEDIOL, 5-bromanyl-2-methoxy-4-[(E)-(3-methylsulfanyl-5-phenyl-1,2,4-triazol-4-yl)iminomethyl]phenol, Casein kinase II subunit alpha, ... | | 著者 | Kinoshita, T, Tsuyuguchi, M. | | 登録日 | 2018-06-07 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.
Sci Adv, 5, 2019
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7EJ9
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