3HUE
 
 | |
3DSC
 | | Crystal structure of P. furiosus Mre11 DNA synaptic complex | | 分子名称: | DNA (5'-D(P*DCP*DAP*DCP*DAP*DAP*DGP*DCP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DGP*DTP*DGP*DAP*DC)-3'), DNA double-strand break repair protein mre11 | | 著者 | Williams, R.S, Moncalian, G, Shin, D.S, Tainer, J.A. | | 登録日 | 2008-07-11 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
Cell(Cambridge,Mass.), 135, 2008
|
|
3DSD
 | | Crystal structure of P. furiosus Mre11-H85S bound to a branched DNA and manganese | | 分子名称: | DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DAP*DCP*DAP*DAP*DGP*DCP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DGP*DTP*DGP*DGP*DAP*DTP*DA)-3'), DNA double-strand break repair protein mre11, MANGANESE (II) ION | | 著者 | Williams, R.S, Moiani, D, Tainer, J.A. | | 登録日 | 2008-07-11 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
Cell(Cambridge,Mass.), 135, 2008
|
|
3HUF
 | | Structure of the S. pombe Nbs1-Ctp1 complex | | 分子名称: | DNA repair and telomere maintenance protein nbs1, Double-strand break repair protein ctp1, THIOCYANATE ION | | 著者 | Williams, R.S, Guenther, G, Tainer, J.A. | | 登録日 | 2009-06-13 | | 公開日 | 2009-10-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Cell(Cambridge,Mass.), 139, 2009
|
|
1T2V
 | | Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide | | 分子名称: | BRCTide-7PS, Breast cancer type 1 susceptibility protein | | 著者 | Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M. | | 登録日 | 2004-04-22 | | 公開日 | 2004-05-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
|
|
1T2U
 | | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F | | 分子名称: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | | 著者 | Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M. | | 登録日 | 2004-04-22 | | 公開日 | 2004-05-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
|
|
1JNX
 | |
1N5O
 | |
8FTK
 | |
8FTM
 | | Setx-ssRNA-ADP-SO4 complex | | 分子名称: | 5'-3' RNA helicase-like protein, ADENOSINE-5'-DIPHOSPHATE, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ... | | 著者 | Williams, R.S, Appel, C.D. | | 登録日 | 2023-01-12 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2.
Mol.Cell, 83, 2023
|
|
8FTH
 | |
3L41
 | | Crystal Structure of S. pombe Brc1 BRCT5-BRCT6 domains in complex with phosphorylated H2A | | 分子名称: | BRCT-containing protein 1, phosphorylated H2A tail | | 著者 | Williams, R.S, Williams, J.S, Guenther, G, Tainer, J.A. | | 登録日 | 2009-12-18 | | 公開日 | 2010-02-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | gammaH2A binds Brc1 to maintain genome integrity during S-phase.
Embo J., 29, 2010
|
|
3L40
 | |
5KIV
 | | Crystal structure of SauMacro (SAV0325) | | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, Protein-ADP-ribose hydrolase, ... | | 著者 | Williams, R.S, Appel, C.D, Feld, G.K, Wallace, B.D. | | 登録日 | 2016-06-17 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure of the sirtuin-linked macrodomain SAV0325 from Staphylococcus aureus.
Protein Sci., 25, 2016
|
|
7UOA
 | | MAGEA4-MTP1 linear peptide complex | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MTP-1, ... | | 著者 | Williams, R.S, Tumbale, P.S. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
J.Med.Chem., 65, 2022
|
|
5INP
 | |
6Q01
 | | TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2 | | 分子名称: | 1,2-ETHANEDIOL, BENZOIC ACID, MAGNESIUM ION, ... | | 著者 | Schellenberg, M.J, Krahn, J.M, Williams, R.S. | | 登録日 | 2019-08-01 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (0.851 Å) | | 主引用文献 | Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2.
Nucleic Acids Res., 48, 2020
|
|
6Q1V
 | | Human DNA Ligase 1 (E592R) Bound to an Adenylated, hydroxyl terminated DNA nick | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... | | 著者 | Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A. | | 登録日 | 2019-08-06 | | 公開日 | 2019-12-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
|
|
3QKR
 | | Mre11 Rad50 binding domain bound to Rad50 | | 分子名称: | DNA double-strand break repair protein mre11, DNA double-strand break repair rad50 ATPase, PHOSPHATE ION | | 著者 | Williams, G.J, Williams, R.S, Arvai, A, Moncalian, G, Tainer, J.A. | | 登録日 | 2011-02-01 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
|
|
3QKU
 | | Mre11 Rad50 binding domain in complex with Rad50 and AMP-PNP | | 分子名称: | DNA double-strand break repair protein mre11, DNA double-strand break repair rad50 ATPase, MAGNESIUM ION, ... | | 著者 | Williams, G.J, Williams, R.S, Arvai, A, Moncalian, G, Tainer, J.A. | | 登録日 | 2011-02-01 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
|
|
3QKS
 | | Mre11 Rad50 binding domain bound to Rad50 | | 分子名称: | DNA double-strand break repair protein mre11, DNA double-strand break repair rad50 ATPase | | 著者 | Williams, G.J, Williams, R.S, Arvai, A, Moncalian, G, Tainer, J.A. | | 登録日 | 2011-02-01 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
|
|
3QKT
 | | Rad50 ABC-ATPase with adjacent coiled-coil region in complex with AMP-PNP | | 分子名称: | DNA double-strand break repair rad50 ATPase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Williams, G.J, Williams, R.S, Arvai, A, Moncalian, G, Tainer, J.A. | | 登録日 | 2011-02-01 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
Nat.Struct.Mol.Biol., 18, 2011
|
|
4X01
 | |
5HT2
 | | Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA, ... | | 著者 | Schellenberg, M.J, Vilas, C.K, Williams, R.S. | | 登録日 | 2016-01-26 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
|
|
4NCH
 | | Crystal Structure of Pyrococcus furiosis Rad50 L802W mutation | | 分子名称: | DNA double-strand break repair Rad50 ATPase, SULFATE ION | | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | | 登録日 | 2013-10-24 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33, 2014
|
|
