4HV3
| Structure of Ricin A chain bound with N-(N-(pterin-7-yl)carbonyl-L-serinyl)-L-tryptophan | 分子名称: | (2S)-2-[[(2S)-2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]-3-oxidanyl-propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid, MALONIC ACID, Ricin, ... | 著者 | Robertus, J.D, Manzano, L.A, Jasheway, K.R, Monzingo, A.F, Saito, R, Pruet, J.M, Wiget, P.A, Anslyn, E.V. | 登録日 | 2012-11-05 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Peptide-conjugated pterins as inhibitors of ricin toxin A. J.Med.Chem., 56, 2013
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4MX1
| Structure of ricin A chain bound with 2-amino-4-oxo-N-(2-(3-phenylureido)ethyl)-3,4-dihydropteridine-7-carboxamide | 分子名称: | 2-amino-4-oxo-N-{2-[(phenylcarbamoyl)amino]ethyl}-3,4-dihydropteridine-7-carboxamide, MALONIC ACID, Ricin A chain, ... | 著者 | Robertus, J.D, Wiget, P.A, Manzano, L.A, Pruet, J.M, Gao, G, Saito, R, Jasheway, K.R, Monzingo, A.F, Anslyn, E.V. | 登録日 | 2013-09-25 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics. Bioorg.Med.Chem.Lett., 23, 2013
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1SBT
| ATOMIC COORDINATES FOR SUBTILISIN BPN (OR NOVO) | 分子名称: | SUBTILISIN BPN' | 著者 | Alden, R.A, Birktoft, J.J, Kraut, J, Robertus, J.D, Wright, C.S. | 登録日 | 1972-08-11 | 公開日 | 1977-01-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Atomic coordinates for subtilisin BPN' (or Novo). Biochem.Biophys.Res.Commun., 45, 1971
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3BPB
| Crystal structure of the dimethylarginine dimethylaminohydrolase H162G adduct with S-methyl-L-thiocitrulline | 分子名称: | N~5~-[(E)-imino(methylsulfanyl)methyl]-L-ornithine, dimethylarginine dimethylaminohydrolase | 著者 | Monzingo, A.F, Linsky, T.W, Stone, E.M, Fast, W, Robertus, J.D. | 登録日 | 2007-12-18 | 公開日 | 2008-06-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Promiscuous partitioning of a covalent intermediate common in the pentein superfamily. Chem.Biol., 15, 2008
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1J1Q
| Structure of Pokeweed Antiviral Protein from Seeds (PAP-S1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antiviral protein S | 著者 | Watanabe, K, Sato, E, Honjo, E, Motoshima, H, Kurokawa, H, Mikami, B, Monzingo, A.F, Robertus, J.D, Fujii, H, Hidaka, A. | 登録日 | 2002-12-14 | 公開日 | 2004-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Pokweed Antiviral Protein from Seeds (PAP-S1) at 1.8 Angstrom Resolution To be published
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1IL5
| STRUCTURE OF RICIN A CHAIN BOUND WITH INHIBITOR 2,5-DIAMINO-4,6-DIHYDROXYPYRIMIDINE (DDP) | 分子名称: | 2,4-DIAMINO-4,6-DIHYDROXYPYRIMIDINE, RICIN A CHAIN | 著者 | Miller, D.J, Ravikumar, K, Shen, H, Suh, J.-K, Kerwin, S.M, Robertus, J.D. | 登録日 | 2001-05-07 | 公開日 | 2002-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition. J.Med.Chem., 45, 2002
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1IL3
| STRUCTURE OF RICIN A CHAIN BOUND WITH INHIBITOR 7-DEAZAGUANINE | 分子名称: | 7-DEAZAGUANINE, RICIN A CHAIN | 著者 | Miller, D.J, Ravikumar, K, Shen, H, Suh, J.-K, Kerwin, S.M, Robertus, J.D. | 登録日 | 2001-05-07 | 公開日 | 2002-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition. J.Med.Chem., 45, 2002
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1IL9
| STRUCTURE OF RICIN A CHAIN BOUND WITH INHIBITOR 8-METHYL-9-OXOGUANINE | 分子名称: | 5-AMINO-2-METHYL-6H-OXAZOLO[5,4-D]PYRIMIDIN-7-ONE, RICIN A CHAIN | 著者 | Miller, D.J, Ravikumar, K, Shen, H, Suh, J.-K, Kerwin, S.M, Robertus, J.D. | 登録日 | 2001-05-07 | 公開日 | 2002-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition. J.Med.Chem., 45, 2002
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1IL4
| STRUCTURE OF RICIN A CHAIN BOUND WITH INHIBITOR 9-DEAZAGUANINE | 分子名称: | 9-DEAZAGUANINE, RICIN A CHAIN | 著者 | Miller, D.J, Ravikumar, K, Shen, H, Suh, J.-K, Kerwin, S.M, Robertus, J.D. | 登録日 | 2001-05-07 | 公開日 | 2002-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition. J.Med.Chem., 45, 2002
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4ESI
| Structure of ricin A chain bound with N-((1H-1,2,3-triazol-4-yl)methyl-2-amino-4-oxo-3,4-dihydropteridine-7-carboxamide | 分子名称: | 2-amino-4-oxo-N-(1H-1,2,3-triazol-5-ylmethyl)-1,4-dihydropteridine-7-carboxamide, Ricin | 著者 | Jasheway, K.R, Pruet, J.M, Ryoto, S, Manzano, L.A, Wiget, P.A, Kamat, I, Anslyn, E.V, Monzingo, A.F, Robertus, J.D. | 登録日 | 2012-04-23 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Optimized 5-membered heterocycle-linked pterins for the inhibition of Ricin Toxin A. ACS Med Chem Lett, 3, 2012
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4QQU
| Crystal structure of the cobalamin-independent methionine synthase enzyme in a closed conformation | 分子名称: | 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, N-[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-gamma-glutamyl-L-glutamic acid, ... | 著者 | Ubhi, D.K, Robertus, J.D. | 登録日 | 2014-06-29 | 公開日 | 2015-01-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | The cobalamin-independent methionine synthase enzyme captured in a substrate-induced closed conformation. J.Mol.Biol., 427, 2015
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3RHY
| Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine | 分子名称: | (4-chloropyridin-2-yl)methanol, N(G),N(G)-dimethylarginine dimethylaminohydrolase | 著者 | Monzingo, A.F, Johnson, C.M, Ke, Z, Yoon, D.-W, Linsky, T.W, Guo, H, Fast, W, Robertus, J.D. | 登録日 | 2011-04-12 | 公開日 | 2011-06-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | On the mechanism of dimethylarginine dimethylaminohydrolase inactivation by 4-halopyridines. J.Am.Chem.Soc., 133, 2011
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3RTI
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3RTJ
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2AAI
| Crystallographic refinement of ricin to 2.5 Angstroms | 分子名称: | RICIN (A CHAIN), RICIN (B CHAIN), alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rutenber, E, Katzin, B.J, Montfort, W, Villafranca, J.E, Ernst, S.R, Collins, E.J, Mlsna, D, Monzingo, A.F, Ready, M.P, Robertus, J.D. | 登録日 | 1993-09-07 | 公開日 | 1994-01-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystallographic refinement of ricin to 2.5 A. Proteins, 10, 1991
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3P8P
| Crystal Structure of Human Dimethylarginine Dimethylaminohydrolase-1 (DDAH-1) variant C274S bound with N5-(1-iminopentyl)-L-ornithine | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~5~-[(1E)-pentanimidoyl]-L-ornithine | 著者 | Monzingo, A.F, Lluis, M, Wang, Y, Fast, W, Robertus, J.D. | 登録日 | 2010-10-14 | 公開日 | 2010-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1. Chemmedchem, 6, 2011
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3P8E
| Crystal structure of human DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 (DDAH-1) covalently bound with N5-(1-iminopentyl)-L-ornithine | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~5~-[(1S)-1-aminopentyl]-L-ornithine | 著者 | Lluis, M, Wang, Y, Monzingo, A.F, Fast, W, Robertus, J.D. | 登録日 | 2010-10-13 | 公開日 | 2010-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4946 Å) | 主引用文献 | Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1. Chemmedchem, 6, 2011
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3PPH
| Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, threonine variant | 分子名称: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 著者 | Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D. | 登録日 | 2010-11-24 | 公開日 | 2011-10-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis. Arch.Biochem.Biophys., 513, 2011
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3PPG
| Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant with zinc | 分子名称: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ZINC ION | 著者 | Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D. | 登録日 | 2010-11-24 | 公開日 | 2011-10-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis. Arch.Biochem.Biophys., 513, 2011
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3PX9
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3PX8
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3PPC
| Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, tyrosine variant with zinc | 分子名称: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, CHLORIDE ION, ZINC ION | 著者 | Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D. | 登録日 | 2010-11-24 | 公開日 | 2011-10-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis. Arch.Biochem.Biophys., 513, 2011
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3PPF
| Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant without zinc | 分子名称: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 著者 | Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D. | 登録日 | 2010-11-24 | 公開日 | 2011-10-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis. Arch.Biochem.Biophys., 513, 2011
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1BR6
| RICIN A CHAIN (RECOMBINANT) COMPLEX WITH PTEROIC ACID | 分子名称: | PROTEIN (RICIN), PTEROIC ACID | 著者 | Hollis, T, Yan, X, Svinth, M, Day, P, Monzingo, A.F, Milne, G.W.A, Robertus, J.D. | 登録日 | 1998-08-27 | 公開日 | 1998-09-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based identification of a ricin inhibitor. J.Mol.Biol., 266, 1997
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1BR5
| RICIN A CHAIN (RECOMBINANT) COMPLEX WITH NEOPTERIN | 分子名称: | NEOPTERIN, PROTEIN (RICIN) | 著者 | Day, P, Yan, X, Hollis, T, Svinth, M, Monzingo, A.F, Milne, G.W.A, Robertus, J.D. | 登録日 | 1998-08-26 | 公開日 | 1998-09-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based identification of a ricin inhibitor. J.Mol.Biol., 266, 1997
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