4ESI
Structure of ricin A chain bound with N-((1H-1,2,3-triazol-4-yl)methyl-2-amino-4-oxo-3,4-dihydropteridine-7-carboxamide
Summary for 4ESI
| Entry DOI | 10.2210/pdb4esi/pdb |
| Related | 1BR5 1BR6 1IFT 1RTC 3PX8 3PX9 |
| Descriptor | Ricin, 2-amino-4-oxo-N-(1H-1,2,3-triazol-5-ylmethyl)-1,4-dihydropteridine-7-carboxamide (3 entities in total) |
| Functional Keywords | ricin, toxin, protein-ligand complex, hydrolase, ribosome inactivating protein, n-glycosidase, pterin, hydrolase-inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Ricinus communis (Castor bean) |
| Total number of polymer chains | 1 |
| Total formula weight | 30224.00 |
| Authors | Jasheway, K.R.,Pruet, J.M.,Ryoto, S.,Manzano, L.A.,Wiget, P.A.,Kamat, I.,Anslyn, E.V.,Monzingo, A.F.,Robertus, J.D. (deposition date: 2012-04-23, release date: 2012-10-31, Last modification date: 2023-09-13) |
| Primary citation | Pruet, J.M.,Saito, R.,Manzano, L.A.,Jasheway, K.R.,Wiget, P.A.,Kamat, I.,Anslyn, E.V.,Robertus, J.D. Optimized 5-membered heterocycle-linked pterins for the inhibition of Ricin Toxin A. ACS Med Chem Lett, 3:588-591, 2012 Cited by PubMed: 23050058DOI: 10.1021/ml300099t PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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