3PX9
RTA in complex with N-(furanylmethyl)-7-carbamoyl-pterin
Summary for 3PX9
| Entry DOI | 10.2210/pdb3px9/pdb |
| Related | 3PX8 |
| Descriptor | Preproricin, 2-amino-N-(furan-2-ylmethyl)-4-oxo-3,4-dihydropteridine-7-carboxamide (3 entities in total) |
| Functional Keywords | ricin, toxin, protein-ligand complex, hydrolase, ribosome inactivating protein, n-glycosidase, pterin, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Ricinus communis (Castor bean) |
| Total number of polymer chains | 1 |
| Total formula weight | 29221.87 |
| Authors | Jasheway, K.R.,Robertus, J.D. (deposition date: 2010-12-09, release date: 2011-06-22, Last modification date: 2024-02-21) |
| Primary citation | Pruet, J.M.,Jasheway, K.R.,Manzano, L.A.,Bai, Y.,Anslyn, E.V.,Robertus, J.D. 7-Substituted pterins provide a new direction for ricin A chain inhibitors. Eur.J.Med.Chem., 46:3608-3615, 2011 Cited by PubMed: 21641093DOI: 10.1016/j.ejmech.2011.05.025 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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