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8WO8
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Crystal Structure of an RNA-binding protein, FAU-1, from Pyrococcus furiosus
分子名称: Probable ribonuclease FAU-1, RNA (5'-R(P*AP*UP*A)-3')
著者Kawai, G, Okada, K, Baba, S, Sato, A, Sakamoto, T, Kanai, A.
登録日2023-10-06
公開日2024-02-14
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Homo-trimeric structure of the ribonuclease for rRNA processing, FAU-1, from Pyrococcus furiosus.
J.Biochem., 175, 2024
2IP4
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Crystal Structure of Glycinamide Ribonucleotide Synthetase from Thermus thermophilus HB8
分子名称: Phosphoribosylamine--glycine ligase, SULFATE ION
著者Sampei, G, Baba, S, Kanagawa, M, Yanai, H, Ishii, T, Kawai, H, Fukai, Y, Ebihara, A, Nakagawa, N, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-10-11
公開日2007-10-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010
2RVO
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Solution structure of a reverse transcriptase recognition site of a LINE RNA from zebrafish
分子名称: RNA (34-MER)
著者Otsu, M, Norose, N, Arai, N, Terao, R, Kajikawa, M, Okada, N, Kawai, G.
登録日2016-02-03
公開日2017-02-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of a reverse transcriptase recognition site of a LINE RNA from zebrafish.
J. Biochem., 162, 2017
2RRC
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Solution Structure of RNA aptamer against AML1 Runt domain
分子名称: 5'-R(P*GP*GP*AP*CP*CP*CP*(AP7)P*CP*CP*AP*CP*GP*GP*CP*GP*AP*GP*GP*UP*CP*CP*A)-3'
著者Nomura, Y, Fujiwara, K, Chiba, M, Fukunaga, J, Tanaka, Y, Iibuchi, H, Tanaka, T, Nakamura, Y, Kawai, G, Kozu, T, Sakamoto, T.
登録日2010-06-23
公開日2011-06-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A novel high affinity RNA motif that mimics DNA in AML1 Runt domain binding
To be Published
1J1H
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Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus
分子名称: Small Protein B
著者Someya, T, Nameki, N, Hosoi, H, Suzuki, S, Hatanaka, H, Fujii, M, Terada, T, Shirouzu, M, Inoue, Y, Shibata, T, Kuramitsu, S, Yokoyama, S, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-12-04
公開日2003-02-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus
FEBS Lett., 535, 2003
3HSB
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Crystal structure of YmaH (Hfq) from Bacillus subtilis in complex with an RNA aptamer
分子名称: Protein hfq, RNA (5'-R(*AP*GP*AP*GP*AP*GP*A)-3')
著者Baba, S, Someya, T, Kumasaka, T, Kawai, G, Nakamura, K.
登録日2009-06-10
公開日2010-06-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq
Nucleic Acids Res., 40, 2012
6JRQ
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Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus
分子名称: 1,2-ETHANEDIOL, Adenylosuccinate synthetase, INOSINIC ACID
著者Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2019-04-05
公開日2020-04-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus HB8
To Be Published
3W7B
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Crystal structure of formyltetrahydrofolate deformylase from Thermus thermophilus HB8
分子名称: Formyltetrahydrofolate deformylase
著者Sampei, G, Yanagida, Y, Ogata, N, Kusano, M, Terao, K, Kawai, H, Fukai, Y, Kanagawa, M, Inoue, Y, Baba, S, Kawai, G.
登録日2013-02-28
公開日2014-01-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures and reaction mechanisms of the two related enzymes, PurN and PurU
J.Biochem., 154, 2013
6J61
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Crystal Structure of Thymidylate Synthase, Thy1, from Thermus thermophilus having an Extra C Terminal Domain
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, PHOSPHATE ION
著者Ogawa, A, Sampei, G, Kawai, G.
登録日2019-01-12
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the flavin-dependent thymidylate synthase Thy1 from Thermus thermophilus with an extra C-terminal domain.
Acta Crystallogr.,Sect.F, 75, 2019
1K2G
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Structural basis for the 3'-terminal guanosine recognition by the group I intron
分子名称: 5'-R(*CP*AP*GP*AP*CP*UP*UP*CP*GP*GP*UP*CP*GP*CP*AP*GP*AP*GP*AP*UP*GP*G)-3'
著者Kitamura, Y, Muto, Y, Watanabe, S, Kim, I, Ito, T, Nishiya, Y, Sakamoto, K, Ohtsuki, T, Kawai, G, Watanabe, K, Hosono, K, Takaku, H, Katoh, E, Yamazaki, T, Inoue, T, Yokoyama, S.
登録日2001-09-27
公開日2002-05-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of an RNA fragment with the P7/P9.0 region and the 3'-terminal guanosine of the tetrahymena group I intron.
RNA, 8, 2002
6IZP
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Solution structure of the complex of naphthyridine carbamate dimer and an RNA with UGGAA-UGGAA pentad
分子名称: 3-[3-[(7-methyl-1,8-naphthyridin-2-yl)carbamoyloxy]propylamino]propyl ~{N}-(7-methyl-1,8-naphthyridin-2-yl)carbamate, RNA (29-MER)
著者Nagano, K, Shibata, T, Nakatani, K, Kawai, G.
登録日2018-12-20
公開日2019-12-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model
Nat Commun, 12, 2021
1L1W
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NMR structure of a SRP19 binding domain in human SRP RNA
分子名称: SRP19 binding domain of SRP RNA
著者Sakamoto, T, Morita, S, Tabata, K, Nakamura, K, Kawai, G.
登録日2002-02-20
公開日2002-05-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a SRP19 binding domain in human SRP RNA.
J.Biochem.(Tokyo), 132, 2002
8I43
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Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues
分子名称: 1-cyclopropyl-N-[3-(dimethylamino)propyl]-7-(4-ethylpiperazin-1-yl)-6-fluoranyl-4-oxidanylidene-quinoline-3-carboxamide, RNA-C-3GC-uucg
著者Ichijo, R, Kamimura, T, Kawai, G.
登録日2023-01-18
公開日2023-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction between a fluoroquinolone derivative KG022 and RNAs: Effect of base pairs 3' adjacent to the bulged residues.
Front Mol Biosci, 10, 2023
8I44
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Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues
分子名称: 1-cyclopropyl-N-[3-(dimethylamino)propyl]-7-(4-ethylpiperazin-1-yl)-6-fluoranyl-4-oxidanylidene-quinoline-3-carboxamide, RNA-C-3AU-uucg
著者Ichijo, R, Kamimura, T, Kawai, G.
登録日2023-01-18
公開日2023-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction between a fluoroquinolone derivative KG022 and RNAs: Effect of base pairs 3' adjacent to the bulged residues.
Front Mol Biosci, 10, 2023
8I46
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Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues
分子名称: 1-cyclopropyl-N-[3-(dimethylamino)propyl]-7-(4-ethylpiperazin-1-yl)-6-fluoranyl-4-oxidanylidene-quinoline-3-carboxamide, RNA-G-3AU-uucg
著者Ichijo, R, Kamimura, T, Kawai, G.
登録日2023-01-18
公開日2023-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction between a fluoroquinolone derivative KG022 and RNAs: Effect of base pairs 3' adjacent to the bulged residues.
Front Mol Biosci, 10, 2023
8I45
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Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues
分子名称: 1-cyclopropyl-N-[3-(dimethylamino)propyl]-7-(4-ethylpiperazin-1-yl)-6-fluoranyl-4-oxidanylidene-quinoline-3-carboxamide, RNA-G-3GC-uucg
著者Ichijo, R, Kamimura, T, Kawai, G.
登録日2023-01-18
公開日2023-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction between a fluoroquinolone derivative KG022 and RNAs: Effect of base pairs 3' adjacent to the bulged residues.
Front Mol Biosci, 10, 2023
1FNX
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SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE AU-RICH ELEMENT
分子名称: AU-RICH RNA ELEMENT, HU ANTIGEN C
著者Inoue, M, Hirao, M, Kasashima, K, Kim, I.-S, Kawai, G, Kigawa, T, Sakamoto, H, Muto, Y, Yokoyama, S.
登録日2000-08-24
公開日2003-06-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of mouse HuC RNA-binding domains complexed with an AU-Rich element reveals determinants of neuronal differentiation
To be Published, 2000
1IT1
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Solution structures of ferrocytochrome c3 from Desulfovibrio vulgaris Miyazaki F
分子名称: HEME C, cytochrome c3
著者Harada, E, Fukuoka, Y, Ohmura, T, Fukunishi, A, Kawai, G, Fujiwara, T, Akutsu, H.
登録日2001-12-29
公開日2002-07-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Redox-coupled conformational alternations in cytochrome c(3) from D. vulgaris Miyazaki F on the basis of its reduced solution structure.
J.Mol.Biol., 319, 2002
8K8B
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Solution structure of a hairpin RNA with the UUCGA loop
分子名称: RNA (5'-R(*GP*GP*AP*UP*CP*CP*UP*UP*UP*CP*GP*AP*GP*GP*GP*AP*UP*CP*C)-3')
著者Ichijo, R, Kawai, G.
登録日2023-07-29
公開日2024-06-05
実験手法SOLUTION NMR
主引用文献NMR analysis of a loop-bulge structure of UUCGA pentaloop.
Biochem.Biophys.Res.Commun., 691, 2024
7FGT
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Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA)
分子名称: DNA (5'-D(*AP*AP*GP*AP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*CP*TP*T)-3'), ~{N}-[3-[3-(dimethylamino)propylamino]-3-oxidanylidene-propyl]-1-methyl-4-[3-[[1-methyl-4-[[1-methyl-4-[3-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazole-2-carboxamide
著者Takase, N, Kawai, G, Igarashi, W, Katagiri, T.
登録日2021-07-28
公開日2022-08-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA)
To be published
7EXY
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T-hairpin structure found in the RNA element involved in the piRNA biogenesis
分子名称: RNA (5'-R(*UP*UP*GP*GP*UP*UP*UP*GP*AP*UP*UP*CP*CP*AP*AP*G)-3')
著者Takase, N, Kawai, G.
登録日2021-05-29
公開日2022-03-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献T-hairpin structure found in the RNA element involved in piRNA biogenesis.
Rna, 28, 2022
8JHP
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Another hairpin structure found in the RNA element involved in piRNA biogenesis
分子名称: RNA (27-MER)
著者Takase, N, Kawai, G.
登録日2023-05-25
公開日2024-05-29
実験手法SOLUTION NMR
主引用文献Another hairpin structure found in the RNA element involved in piRNA biogenesis
To Be Published
7FJ0
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Interaction between a fluoroquinolone derivative and RNAs with a single bulge
分子名称: 1-cyclopropyl-N-[3-(dimethylamino)propyl]-7-(4-ethylpiperazin-1-yl)-6-fluoranyl-4-oxidanylidene-quinoline-3-carboxamide, RNA (5'-R(*GP*GP*AP*UP*GP*CP*UP*UP*AP*CP*UP*CP*AP*GP*CP*GP*AP*UP*CP*C)-3')
著者Nagano, K, Kamimura, T, Kawai, G.
登録日2021-08-02
公開日2021-12-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction between a fluoroquinolone derivative and RNAs with a single bulge.
J.Biochem., 171, 2022
7FHI
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Interaction between a fluoroquinolone derivative and RNAs with a single bulge
分子名称: 1-cyclopropyl-N-[3-(dimethylamino)propyl]-7-(4-ethylpiperazin-1-yl)-6-fluoranyl-4-oxidanylidene-quinoline-3-carboxamide, RNA (5'-R(*GP*GP*AP*UP*GP*CP*UP*UP*AP*CP*UP*CP*AP*GP*CP*CP*AP*UP*CP*C)-3')
著者Nagano, K, Kamimura, T, Kawai, G.
登録日2021-07-29
公開日2021-12-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction between a fluoroquinolone derivative and RNAs with a single bulge.
J.Biochem., 171, 2022
2YRW
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Crystal structure of GAR synthetase from Geobacillus kaustophilus
分子名称: PHOSPHATE ION, Phosphoribosylglycinamide synthetase
著者Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-03
公開日2007-10-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010

 

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