1W3B
 
 | | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | | 分子名称: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | | 著者 | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | | 登録日 | 2004-07-14 | | 公開日 | 2004-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
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2VXG
 | | Crystal structure of the conserved C-terminal region of Ge-1 | | 分子名称: | CG6181-PA, ISOFORM A | | 著者 | Jinek, M, Eulalio, A, Lingel, A, Helms, S, Conti, E, Izaurralde, E. | | 登録日 | 2008-07-04 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The C-Terminal Region of Ge-1 Presents Conserved Structural Features Required for P-Body Localization.
RNA, 14, 2008
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2X04
 | | Crystal structure of the PABC-TNRC6C complex | | 分子名称: | POLYADENYLATE-BINDING PROTEIN 1, SULFATE ION, TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN | | 著者 | Jinek, M, Fabian, M.R, Coyle, S.M, Sonenberg, N, Doudna, J.A. | | 登録日 | 2009-12-04 | | 公開日 | 2010-01-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structural Insights Into the Human Gw182-Pabc Interaction in Microrna-Mediated Deadenylation
Nat.Struct.Mol.Biol., 17, 2010
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2J0A
 | | Structure of the catalytic domain of mouse Manic Fringe | | 分子名称: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, POTASSIUM ION, SULFATE ION | | 著者 | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | | 登録日 | 2006-08-01 | | 公開日 | 2006-09-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
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2J0B
 | | Structure of the catalytic domain of mouse Manic Fringe in complex with UDP and manganese | | 分子名称: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, MANGANESE (II) ION, POTASSIUM ION, ... | | 著者 | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | | 登録日 | 2006-08-01 | | 公開日 | 2006-09-04 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
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4CMQ
 | | Crystal structure of Mn-bound S.pyogenes Cas9 | | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION | | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | | 登録日 | 2014-01-17 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
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4CMP
 | | Crystal structure of S. pyogenes Cas9 | | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | | 登録日 | 2014-01-16 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
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2Y35
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6F9S
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6FDL
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6I1K
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6I1L
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4C9D
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4C8Y
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4C98
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4C97
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4C8Z
 | | Cas6 (TTHA0078) product complex | | 分子名称: | CAS6A, POTASSIUM ION, R1 REPEAT RNA CLEAVAGE PRODUCT, ... | | 著者 | Jinek, M, Niewoehner, O, Doudna, J.A. | | 登録日 | 2013-10-02 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
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5FQ5
 | | Crystal structure of Cas9-sgRNA-DNA complex solved by native SAD phasing | | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | | 著者 | Olieric, V, Weinert, T, Finke, A, Anders, C, Jinek, M, Wang, M. | | 登録日 | 2015-12-07 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.136 Å) | | 主引用文献 | Data-Collection Strategy for Challenging Native Sad Phasing.
Acta Crystallogr.,Sect.D, 72, 2016
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7Z4E
 | | SpCas9 bound to 8-nucleotide complementary DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 8 nucleotide complementary DNA substrate, Target strand of 8 nucleotide complementary DNA substrate, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-03-03 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | | 主引用文献 | R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
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7Z4K
 | | SpCas9 bound to 10-nucleotide complementary DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 10-nucleotide complementary DNA substrate, Target strand of 10-nucleotide complementary DNA substrate, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-03-04 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | | 主引用文献 | R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
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7Z4G
 | | SpCas9 bound to 12-nucleotide complementary DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 12-nucleotide complementary DNA substrate, Target strand of 12-nucleotide complementary DNA substrate, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-03-03 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
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7Z4D
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7Z4L
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7Z4C
 | | SpCas9 bound to 6 nucleotide complementary DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 6 nucleotide complementary DNA substrate, Target strand of 6 nucleotide complementary DNA substrate, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-03-03 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
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7Z4I
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