2CKB
 
 | | STRUCTURE OF THE 2C/KB/DEV8 COMPLEX | | 分子名称: | ALPHA, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ... | | 著者 | Garcia, K.C, Degano, M, Wilson, I.A. | | 登録日 | 1998-01-14 | | 公開日 | 1998-04-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science, 279, 1998
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1TCR
 | | MURINE T-CELL ANTIGEN RECEPTOR 2C CLONE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Garcia, K.C, Degano, M, Stanfield, R.L, Wilson, I.A. | | 登録日 | 1996-09-12 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
Science, 274, 1996
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2E7L
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5UK5
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3BPN
 | | Crystal structure of the IL4-IL4R-IL13Ra ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13 receptor alpha-1 chain, Interleukin-4, ... | | 著者 | Garcia, K.C. | | 登録日 | 2007-12-18 | | 公開日 | 2008-02-05 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
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3BPL
 | | Crystal structure of the IL4-IL4R-Common Gamma ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Garcia, K.C. | | 登録日 | 2007-12-18 | | 公開日 | 2008-02-05 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
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3BPO
 | | Crystal structure of the IL13-IL4R-IL13Ra ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 13, ... | | 著者 | Garcia, K.C. | | 登録日 | 2007-12-18 | | 公開日 | 2008-02-05 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
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2NYK
 | | Crystal structure of m157 from mouse cytomegalovirus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, M157 | | 著者 | Garcia, K.C. | | 登録日 | 2006-11-20 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2OI9
 | | Structure of the 2C/Ld/QL9 allogeneic complex | | 分子名称: | Major Histocompatibility Complex protein, T cell receptor alpha chain, T cell receptor beta chain, ... | | 著者 | Garcia, K.C, Colf, L.A. | | 登録日 | 2007-01-10 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | How a single T cell receptor recognizes both self and foreign MHC.
Cell(Cambridge,Mass.), 129, 2007
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7N2P
 | | AS4.3-RNASEH2b-HLA*B27 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | | 著者 | Yang, X, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-05-29 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Nature, 612, 2022
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1JDN
 | | Crystal Structure of Hormone Receptor | | 分子名称: | ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, CHLORIDE ION, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | He, X.-L, Chow, D.-C, Martick, M.M, Garcia, K.C. | | 登録日 | 2001-06-14 | | 公開日 | 2001-09-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.
Science, 293, 2001
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1SG1
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1G6R
 | | A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX | | 分子名称: | ALPHA T CELL RECEPTOR, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ... | | 著者 | Degano, M, Garcia, K.C, Apostolopoulos, V, Rudolph, M.G, Teyton, L, Wilson, I.A. | | 登録日 | 2000-11-07 | | 公開日 | 2000-11-15 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A functional hot spot for antigen recognition in a superagonist TCR/MHC complex.
Immunity, 12, 2000
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1GNA
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1GNB
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2RKC
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1XFD
 | | Structure of a human A-type Potassium Channel Accelerating factor DPPX, a member of the dipeptidyl aminopeptidase family | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl aminopeptidase-like protein 6, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Strop, P, Bankovich, A.J, Hansen, K.C, Garcia, K.C, Brunger, A.T. | | 登録日 | 2004-09-14 | | 公開日 | 2004-10-26 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family
J.Mol.Biol., 343, 2004
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1U3H
 | | Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A | | 分子名称: | H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain, ... | | 著者 | Maynard, J, Petersson, K, Wilson, D.H, Adams, E.J, Blondelle, S.E, Boulanger, M.J, Wilson, D.B, Garcia, K.C. | | 登録日 | 2004-07-21 | | 公開日 | 2005-05-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity
Immunity, 22, 2005
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4KJY
 | | Complex of high-affinity SIRP alpha variant FD6 with CD47 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, High-affinity SIRPa variant FD6, Leukocyte surface antigen CD47, ... | | 著者 | Ring, A.M, Ozkan, E, Ho, C.C.M, Garcia, K.C. | | 登録日 | 2013-05-04 | | 公開日 | 2013-06-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Engineered SIRP alpha variants as immunotherapeutic adjuvants to anticancer antibodies.
Science, 341, 2013
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8VSP
 | | Cryo-EM structure of human invariant chain in complex with HLA-DQ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, ... | | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | | 登録日 | 2024-01-24 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structural insights into human MHC-II association with invariant chain.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VRW
 | | Cryo-EM structure of human invariant chain in complex with HLA-DR15 | | 分子名称: | HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... | | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | | 登録日 | 2024-01-22 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structural insights into human MHC-II association with invariant chain.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VSJ
 | | Engineered peptide-specific binder in complex with HLA-DR1/CLIP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Class-II-associated invariant chain peptide, HLA class II histocompatibility antigen DR beta chain, ... | | 著者 | Jude, K.M, Yang, X, Du, H, Kassardjian, A, Julien, J.-P, Huang, P, Garcia, K.C. | | 登録日 | 2024-01-24 | | 公開日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.28 Å) | | 主引用文献 | Differentiating MHC-II antigens with a single loop
To Be Published
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6NE1
 | | Designed repeat protein in complex with Fz4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Pfs, ... | | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | | 登録日 | 2018-12-15 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.011 Å) | | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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6NE4
 | | Designed repeat protein specifically in complex with Fz7CRD | | 分子名称: | 1,2-ETHANEDIOL, Designed repeat binding protein, Frizzled-7, ... | | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | | 登録日 | 2018-12-16 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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5T5W
 | | Structure of an affinity matured lambda-IFN/IFN-lambdaR1/IL-10Rbeta receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon lambda receptor 1, Interferon lambda-3, ... | | 著者 | Mendoza, J.L, Jude, K.M, Garcia, K.C. | | 登録日 | 2016-08-31 | | 公開日 | 2017-03-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.847 Å) | | 主引用文献 | The IFN-lambda-IFN-lambda R1-IL-10R beta Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.
Immunity, 46, 2017
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