2K0N
 
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5WB5
 | | Leishmania IF4E-1 bound to Leishmania 4E-IP1 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Putative eukaryotic translation initiation factor eIF-4E, Uncharacterized protein | | 著者 | Leger-Abraham, M, Meleppattu, S, Arthanari, H, Zinoviev, A, Boeszoermenyi, A, Wagner, G, Shapira, M. | | 登録日 | 2017-06-27 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.
Nucleic Acids Res., 46, 2018
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5BXV
 | | eIF4E complex | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1 | | 著者 | Sekiyama, N, Arthanari, H, Papdopoulos, E, Rodriguez-Mias, R.A, Wagner, G, Leger-Abraham, M. | | 登録日 | 2015-06-09 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4D7X
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5A4H
 | | Solution structure of the lipid droplet anchoring peptide of CGI-58 bound to DPC micelles | | 分子名称: | 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 | | 著者 | Boeszoermenyi, A, Arthanari, H, Wagner, G, Nagy, H.M, Zangger, K, Lindermuth, H, Oberer, M. | | 登録日 | 2015-06-09 | | 公開日 | 2015-09-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a Cgi-58 Motif Provides the Molecular Basis of Lipid Droplet Anchoring.
J.Biol.Chem., 290, 2015
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2LYC
 | | Structure of C-terminal domain of Ska1 | | 分子名称: | Spindle and kinetochore-associated protein 1 homolog | | 著者 | Boeszoermenyi, A, Schmidt, J.C, Markus, M, Oberer, M, Cheeseman, I.M, Wagner, G, Arthanari, H. | | 登録日 | 2012-09-14 | | 公開日 | 2012-10-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The kinetochore-bound ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments.
Dev.Cell, 23, 2012
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2ROQ
 | | Solution Structure of the thiolation-thioesterase di-domain of enterobactin synthetase component F | | 分子名称: | Enterobactin synthetase component F | | 著者 | Frueh, D.P, Arthanari, H, Koglin, A, Vosburg, D.A, Bennett, A.E, Walsh, C.T, Wagner, G. | | 登録日 | 2008-04-05 | | 公開日 | 2008-08-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase
Nature, 454, 2008
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5IJ4
 | | Solution structure of AN1-type zinc finger domain from Cuz1 (Cdc48 associated ubiquitin-like/zinc-finger protein-1) | | 分子名称: | CDC48-associated ubiquitin-like/zinc finger protein 1, ZINC ION | | 著者 | Sun, Z.-Y.J, Hanna, J, Wagner, G, Bhanu, M.K, Allan, M, Arthanari, H. | | 登録日 | 2016-03-01 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins.
Plos One, 11, 2016
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5A3G
 | | Structure of herpesvirus nuclear egress complex subunit M50 | | 分子名称: | M50 | | 著者 | Leigh, K.E, Boeszoermenyi, A, Mansueto, M.S, Sharma, M, Filman, D.J, Coen, D.M, Wagner, G, Hogle, J.M, Arthanari, H. | | 登録日 | 2015-06-01 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a Herpesvirus Nuclear Egress Complex Subunit Reveals an Interaction Groove that is Essential for Viral Replication
Proc.Natl.Acad.Sci.USA, 112, 2015
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7U20
 | | Crystal structure of human METTL1 and WDR4 complex | | 分子名称: | SULFATE ION, tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 | | 著者 | Li, J, Nowak, R.P, Fischer, E.S, Gregory, R. | | 登録日 | 2022-02-22 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
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7P2G
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8CTI
 | | Cryo-EM structure of human METTL1-WDR4-tRNA(Val) complex | | 分子名称: | tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, tRNA-Val-TAC-2-1 | | 著者 | Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fischer, E.S, Gregory, R.I. | | 登録日 | 2022-05-14 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
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8CTH
 | | Cryo-EM structure of human METTL1-WDR4-tRNA(Phe) complex | | 分子名称: | Phe-tRNA, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase, ... | | 著者 | Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fishcer, E.S, Gregory, R.I. | | 登録日 | 2022-05-14 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
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2RVH
 | | NMR structure of eIF1 | | 分子名称: | Eukaryotic translation initiation factor eIF-1 | | 著者 | Nagata, T, Obayashi, E, Asano, K. | | 登録日 | 2015-10-16 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5
Cell Rep, 18, 2017
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8CN1
 | | hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1 | | 分子名称: | Disks large homolog 1, GLU-THR-GLU-VAL, SULFATE ION | | 著者 | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | | 登録日 | 2023-02-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Antiviral Res., 217, 2023
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8CN3
 | | hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1 | | 分子名称: | Disks large homolog 1, GLU-THR-GLU-VAL | | 著者 | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | | 登録日 | 2023-02-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Antiviral Res., 217, 2023
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7MYX
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5H7U
 | | NMR structure of eIF3 36-163 | | 分子名称: | Eukaryotic translation initiation factor 3 subunit C | | 著者 | Nagata, T, Obayashi, E. | | 登録日 | 2016-11-21 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.
Cell Rep, 18, 2017
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8CAK
 | | Crystal structure of dehydrogenase domain of Cylindrospermum stagnale NADPH-Oxidase 5 (NOX5) in complex with M41 | | 分子名称: | 1,2-ETHANEDIOL, 15-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-14-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(16),2(7),3,5,9,11,13(17),14-octaen-8-one, DIMETHYL SULFOXIDE, ... | | 著者 | Reis, J, Mattevi, A. | | 登録日 | 2023-01-24 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Targeting ROS production through inhibition of NADPH oxidases.
Nat.Chem.Biol., 19, 2023
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8CAL
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8CAP
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8CAO
 | | Crystal structure of dehydrogenase domain of Cylindrospermum stagnale NADPH-Oxidase 5 (NOX5) in complex with CA24 | | 分子名称: | 1,2-ETHANEDIOL, 8-[2-(4-cyclohexylphenyl)quinolin-4-yl]carbonyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Reis, J, Mattevi, A. | | 登録日 | 2023-01-24 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Targeting ROS production through inhibition of NADPH oxidases.
Nat.Chem.Biol., 19, 2023
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8CB0
 | | Crystal structure of dehydrogenase domain of Cylindrospermum stagnale NADPH-Oxidase 5 (NOX5) in complex with M41 and NADP+ | | 分子名称: | 1,2-ETHANEDIOL, 15-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-14-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(16),2(7),3,5,9,11,13(17),14-octaen-8-one, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Reis, J, Mattevi, A. | | 登録日 | 2023-01-24 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Targeting ROS production through inhibition of NADPH oxidases.
Nat.Chem.Biol., 19, 2023
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6MF8
 | | TCR alpha transmembrane domain | | 分子名称: | T-cell receptor alpha chain C region | | 著者 | Brazin, K.N, Reinherz, E.L. | | 登録日 | 2018-09-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The T Cell Antigen Receptor alpha Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Immunity, 49, 2018
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4TQC
 | | The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G | | 分子名称: | (2S)-3-(4-amino-3-nitrophenyl)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinyl}propanoic acid, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E | | 著者 | Papadopoulos, E, Jenni, S, Wagner, G. | | 登録日 | 2014-06-10 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
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