8CN3

hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1

Summary for 8CN3

• Entry DOI: 10.2210/pdb8cn3/pdb
• Descriptor: Disks large homolog 1, GLU-THR-GLU-VAL, ... (4 entities in total)
• Functional Keywords: htlv-1; tax-1; hdlg1; pbm, protein protein interaction, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 25717.33

Authors

Maseko, S.,Sogues, A.,Volkov, A.,Remaut, H.,Twizere, J.C. (deposition date: 2023-02-21, release date: 2023-08-02, Last modification date: 2023-08-09)

• Primary citation: Maseko, S.B.,Brammerloo, Y.,Van Molle, I.,Sogues, A.,Martin, C.,Gorgulla, C.,Plant, E.,Olivet, J.,Blavier, J.,Ntombela, T.,Delvigne, F.,Arthanari, H.,El Hajj, H.,Bazarbachi, A.,Van Lint, C.,Salehi-Ashtiani, K.,Remaut, H.,Ballet, S.,Volkov, A.N.,Twizere, J.C.; Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.; Antiviral Res., 217:105675-105675, 2023; PubMed: 37481039; DOI: 10.1016/j.antiviral.2023.105675

Experimental method

X-RAY DIFFRACTION (2.71 Å)