8CN3
hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1
Summary for 8CN3
Entry DOI | 10.2210/pdb8cn3/pdb |
Descriptor | Disks large homolog 1, GLU-THR-GLU-VAL, ... (4 entities in total) |
Functional Keywords | htlv-1; tax-1; hdlg1; pbm, protein protein interaction, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 25717.33 |
Authors | Maseko, S.,Sogues, A.,Volkov, A.,Remaut, H.,Twizere, J.C. (deposition date: 2023-02-21, release date: 2023-08-02, Last modification date: 2024-06-19) |
Primary citation | Maseko, S.B.,Brammerloo, Y.,Van Molle, I.,Sogues, A.,Martin, C.,Gorgulla, C.,Plant, E.,Olivet, J.,Blavier, J.,Ntombela, T.,Delvigne, F.,Arthanari, H.,El Hajj, H.,Bazarbachi, A.,Van Lint, C.,Salehi-Ashtiani, K.,Remaut, H.,Ballet, S.,Volkov, A.N.,Twizere, J.C. Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction. Antiviral Res., 217:105675-105675, 2023 Cited by PubMed: 37481039DOI: 10.1016/j.antiviral.2023.105675 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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