5TWY
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5TWU
| Structure of Maternal Embryonic Leucine Zipper Kinase | 分子名称: | Maternal embryonic leucine zipper kinase | 著者 | Li, Q, Seo, H.-S, Huang, H.-T, Gray, N.S, Dhe-Paganon, S, Eck, M.J. | 登録日 | 2016-11-14 | 公開日 | 2017-11-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | 主引用文献 | MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife, 6, 2017
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5TWL
| Structure of Maternal Embryonic Leucine Zipper Kinase | 分子名称: | 9-(3,5-dichloro-4-hydroxyphenyl)-1-{trans-4-[(dimethylamino)methyl]cyclohexyl}-3,4-dihydropyrimido[5,4-c]quinolin-2(1H)-one, Maternal embryonic leucine zipper kinase | 著者 | Seo, H.-S, Huang, H.-T, Gray, N.S, Dhe-Paganon, S. | 登録日 | 2016-11-14 | 公開日 | 2017-11-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife, 6, 2017
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5TWZ
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7F3N
| Structure of PopP2 in apo form | 分子名称: | Type III effector protein popp2 | 著者 | Xia, Y, Zhang, Z.M. | 登録日 | 2021-06-16 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.351856 Å) | 主引用文献 | Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase. Nat Commun, 12, 2021
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8VF6
| Crystal structure of Serine/threonine-protein kinase 33 (STK33) Kinase Domain in complex with inhibitor CDD-2211 | 分子名称: | Serine/threonine-protein kinase 33, {3-[([1,1'-biphenyl]-2-yl)ethynyl]-1H-indazol-5-yl}[(3R)-3-(dimethylamino)pyrrolidin-1-yl]methanone | 著者 | Ta, H.M, Kim, C, Ku, K.A, Matzuk, M.M. | 登録日 | 2023-12-21 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science, 384, 2024
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7BWJ
| crystal structure of SARS-CoV-2 antibody with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | 著者 | Wang, X, Ge, J. | 登録日 | 2020-04-14 | 公開日 | 2020-06-03 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature, 584, 2020
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5GW8
| Crystal structure of a putative DAG-like lipase (MgMDL2) from Malassezia globosa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | 著者 | Xu, J, Xu, H, Liu, J. | 登録日 | 2016-09-09 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Malassezia globosa MgMDL2 lipase: Crystal structure and rational modification of substrate specificity. Biochem. Biophys. Res. Commun., 488, 2017
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4G2M
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8X83
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8X82
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4G0B
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3S34
| Structure of the 1121B Fab fragment | 分子名称: | 1121B Fab heavy chain, 1121B Fab light chain, PHOSPHATE ION | 著者 | Franklin, M.C. | 登録日 | 2011-05-17 | 公開日 | 2011-08-24 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies. Structure, 19, 2011
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8X84
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4FX4
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3SW2
| X-ray crystal structure of human FXA in complex with 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide | 分子名称: | 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide, CALCIUM ION, Coagulation factor X, ... | 著者 | Klei, H.E. | 登録日 | 2011-07-13 | 公開日 | 2011-11-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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8XQ4
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8XQ8
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8XQA
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8XQ7
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6KPF
| Cryo-EM structure of a class A GPCR with G protein complex | 分子名称: | 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Li, X.T, Hua, T, Wu, L.J, Makriyannis, A, Shen, L, Wang, Y.X, Liu, Z.J. | 登録日 | 2019-08-15 | 公開日 | 2020-02-12 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures. Cell, 180, 2020
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8XPQ
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8XQ9
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5HW5
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8WTI
| Crystal structure of the SARS-CoV-2 main protease in complex with 20j | 分子名称: | 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Zeng, R, Zhao, X, Yang, S.Y, Lei, J. | 登録日 | 2023-10-18 | 公開日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery of alpha-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups. Bioorg.Chem., 143, 2024
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