4FX4
Crystal structure of M. tuberculosis transcriptional regulator MOSR (Rv1049) in compex with DNA
Summary for 4FX4
Entry DOI | 10.2210/pdb4fx4/pdb |
Related | 4FX0 |
Descriptor | DNA (5'-D(*TP*AP*CP*AP*GP*AP*TP*TP*CP*GP*TP*GP*TP*AP*GP*CP*TP*AP*CP*AP*CP*GP*AP*AP*TP*CP*TP*GP*T)-3'), PROBABLE TRANSCRIPTIONAL REPRESSOR PROTEIN, PHOSPHATE ION (3 entities in total) |
Functional Keywords | helix-turn-helix, transcriptional repressor, dna binding, transcription regulator-dna complex, transcription regulator/dna |
Biological source | Mycobacterium tuberculosis More |
Total number of polymer chains | 4 |
Total formula weight | 50598.87 |
Authors | Brugarolas, P.,He, C. (deposition date: 2012-07-02, release date: 2012-09-26, Last modification date: 2023-12-06) |
Primary citation | Brugarolas, P.,Movahedzadeh, F.,Wang, Y.,Zhang, N.,Bartek, I.L.,Gao, Y.N.,Voskuil, M.I.,Franzblau, S.G.,He, C. The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis. J.Biol.Chem., 287:37703-37712, 2012 Cited by PubMed: 22992749DOI: 10.1074/jbc.M112.388611 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1001 Å) |
Structure validation
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