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6U2D
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BU of 6u2d by Molmil
PmtCD peptide exporter basket domain
分子名称: ABC transporter ATP-binding protein, IODIDE ION, SULFATE ION
著者Zeytuni, N, Strynadka, N.C.J.
登録日2019-08-19
公開日2020-10-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
5XEP
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BU of 5xep by Molmil
Crystal structure of BRP39, a chitinase-like protein, at 2.6 Angstorm resolution
分子名称: 1,2-ETHANEDIOL, Chitinase-3-like protein 1
著者Mohanty, A.K, Fisher, A.J, Choudhary, S, Kaushik, J.K.
登録日2017-04-05
公開日2018-04-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of BRP39, a signalling glycoprotein expressed during mammary gland apoptosis.
To be published
7FJI
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BU of 7fji by Molmil
human Pol III elongation complex
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Hou, H, Xu, Y.
登録日2021-08-04
公開日2021-10-27
最終更新日2021-11-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
7FJJ
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BU of 7fjj by Molmil
human Pol III pre-termination complex
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Hou, H, Xu, Y.
登録日2021-08-04
公開日2021-10-27
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
5YGI
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BU of 5ygi by Molmil
Crystal structure of human FPPS in complex with an inhibitor THZ93
分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Li, X.
登録日2017-09-23
公開日2018-09-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.177 Å)
主引用文献The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Cell, 175, 2018
7JN4
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BU of 7jn4 by Molmil
Rubisco in the apo state
分子名称: Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, chloroplastic
著者Matthies, D, Jonikas, M.C, He, S.
登録日2020-08-03
公開日2020-11-18
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献The structural basis of Rubisco phase separation in the pyrenoid.
Nat.Plants, 6, 2020
7JFO
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BU of 7jfo by Molmil
EPYC1(49-72)-bound Rubisco
分子名称: LCI5, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, ...
著者Matthies, D, Jonikas, M.C, He, S.
登録日2020-07-17
公開日2020-11-18
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (2.13 Å)
主引用文献The structural basis of Rubisco phase separation in the pyrenoid.
Nat.Plants, 6, 2020
7JSX
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BU of 7jsx by Molmil
EPYC1(106-135) peptide-bound Rubisco
分子名称: EPYC1, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, ...
著者Matthies, D, He, S, Jonikas, M.C.
登録日2020-08-16
公開日2020-11-18
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (2.06 Å)
主引用文献The structural basis of Rubisco phase separation in the pyrenoid.
Nat.Plants, 6, 2020
6A9F
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BU of 6a9f by Molmil
Crystal structure of a cyclase from Fischerella sp. TAU in complex with 4-(1H-Indol-3-yl)butan-2-one
分子名称: 4-(1~{H}-indol-3-yl)butan-2-one, CALCIUM ION, GLYCEROL, ...
著者Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2018-07-13
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
6A99
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BU of 6a99 by Molmil
Crystal structure of a Stig cyclases Fisc from Fischerella sp. TAU in complex with (3Z)-3-(1-methyl-2-pyrrolidinylidene)-3H-indole
分子名称: (3~{Z})-3-(1-methylpyrrolidin-2-ylidene)indole, CALCIUM ION, MAGNESIUM ION, ...
著者Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2018-07-12
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
6ADU
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BU of 6adu by Molmil
Crystal structure of an enzyme in complex with ligand C
分子名称: (3~{Z})-3-(1-methylpyrrolidin-2-ylidene)indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Tan, X.K, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2018-08-02
公開日2019-08-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement.
Angew.Chem.Int.Ed.Engl., 57, 2018
8HDJ
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BU of 8hdj by Molmil
Periplasmic domain of RsgI2 of Clostridium thermocellum
分子名称: Anti-sigma-I factor RsgI2, Periplasmic domain of RsgI2
著者Chen, C, Dong, S, Feng, Y.G.
登録日2022-11-04
公開日2023-05-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Essential autoproteolysis of bacterial anti-sigma factor RsgI for transmembrane signal transduction.
Sci Adv, 9, 2023
8HER
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BU of 8her by Molmil
Solution structure of the periplasmic domain of RsgI6 from Clostridium thermocellum
分子名称: Anti-sigma factor
著者Chen, C, Feng, Y.
登録日2022-11-08
公開日2023-05-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Essential autoproteolysis of bacterial anti-sigma factor RsgI for transmembrane signal transduction.
Sci Adv, 9, 2023
8HEP
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BU of 8hep by Molmil
Solution structure of the periplasmic domain of the anti-sigma factor RsgI1 from Clostridium thermocellum
分子名称: Anti-sigma factor
著者Chen, C, Feng, Y.
登録日2022-11-08
公開日2023-05-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Essential autoproteolysis of bacterial anti-sigma factor RsgI for transmembrane signal transduction.
Sci Adv, 9, 2023
8HEQ
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BU of 8heq by Molmil
Solution structure of the periplasmic domain of the anti-sigma factor RsgI2 from Clostridium thermocellum
分子名称: Anti-sigma-I factor RsgI2
著者Chen, C, Feng, Y.
登録日2022-11-08
公開日2023-05-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Essential autoproteolysis of bacterial anti-sigma factor RsgI for transmembrane signal transduction.
Sci Adv, 9, 2023
6B88
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BU of 6b88 by Molmil
E. coli LepB in complex with GNE0775 ((4S,7S,10S)-10-((S)-4-amino-2-(2-(4-(tert-butyl)phenyl)-4-methylpyrimidine-5-carboxamido)-N-methylbutanamido)-16,26-bis(2-aminoethoxy)-N-(2-iminoethyl)-7-methyl-6,9-dioxo-5,8-diaza-1,2(1,3)-dibenzenacyclodecaphane-4-carboxamide)
分子名称: (8S,11S,14S)-14-{[(2S)-4-amino-2-{[2-(4-tert-butylphenyl)-4-methylpyrimidine-5-carbonyl]amino}butanoyl](methyl)amino}-3,18-bis(2-aminoethoxy)-N-[(2Z)-2-iminoethyl]-11-methyl-10,13-dioxo-9,12-diazatricyclo[13.3.1.1~2,6~]icosa-1(19),2(20),3,5,15,17-hexaene-8-carboxamide, PENTAETHYLENE GLYCOL, Signal peptidase I
著者Murray, J.M, Rouge, L.
登録日2017-10-05
公開日2018-10-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献Optimized arylomycins are a new class of Gram-negative antibiotics.
Nature, 561, 2018
6BPD
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BU of 6bpd by Molmil
Plasmodium vivax invasion blocking monoclonal antibody 10B12
分子名称: Monoclonal antibody 10B12 Fab heavy chain, Monoclonal antibody 10B12 Fab light chain
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPA
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BU of 6bpa by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 3E9
分子名称: BROMIDE ION, Monoclonal antibody 3E9 Fab heavy chain, Monoclonal antibody 3E9 Fab light chain, ...
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPE
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BU of 6bpe by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 6H1
分子名称: Monoclonal antibody 6H1 Fab heavy chain, Monoclonal antibody 6H1 Fab light chain, Reticulocyte binding protein 2, ...
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPB
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BU of 6bpb by Molmil
Plasmodium vivax invasion blocking monoclonal antibody 4F7
分子名称: Monoclonal antibody 4F7 Fab heavy chain, Monoclonal antibody 4F7 Fab light chain
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPC
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BU of 6bpc by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 4F7
分子名称: Monoclonal antibody 4F7 Fab heavy chain, Monoclonal antibody 4F7 Fab light chain, Reticulocyte binding protein 2, ...
著者Gruszczyk, J, Chan, L.J, Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
8XOM
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BU of 8xom by Molmil
Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE
分子名称: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ...
著者Zhang, P.F, Liu, Z.
登録日2024-01-01
公開日2024-07-17
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 598, 2024
8XOL
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BU of 8xol by Molmil
Cryo-EM structure of human ABCC4 with ANP bound in NBD1
分子名称: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ...
著者Zhang, P.F, Liu, Z.
登録日2024-01-01
公開日2024-07-17
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 598, 2024
8XOK
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BU of 8xok by Molmil
Cryo-EM structure of human ABCC4
分子名称: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, PALMITIC ACID
著者Zhang, P.F, Liu, Z.
登録日2024-01-01
公開日2024-07-24
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 598, 2024
3RIK
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BU of 3rik by Molmil
The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease
分子名称: (3S,4R,5R,6S)-1-(2-hydroxyethyl)azepane-3,4,5,6-tetrol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ...
著者Orwig, S.D, Lieberman, R.L.
登録日2011-04-13
公開日2012-03-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease
Biochemistry, 50, 2011

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