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8VWX
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BU of 8vwx by Molmil
Human Bcl-2 (G101V Mutant)/Bcl-xL Chimera Fused to Maltose-Binding Protein
分子名称: Maltose/maltodextrin-binding periplasmic protein fused to apoptosis regulator Bcl-2/Bcl-xL chimera
著者Baird, J, Holliday, M.
登録日2024-02-02
公開日2024-10-02
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Complementary Backbone and Side-Chain Analysis of Drug-Protein Interactions: Combining Hydrogen/Deuterium Exchange and Protein Oxidative Footprinting to Discriminate the Binding of Small Molecule Therapeutics
To Be Published
2G6Q
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BU of 2g6q by Molmil
Crystal structure of ING2 PHD finger in complex with H3K4Me3 peptide
分子名称: H3K4Me3 peptide, Inhibitor of growth protein 2, ZINC ION
著者Pena, P.V, Zhao, R, Kutateladze, T.G.
登録日2006-02-24
公開日2006-07-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2.
Nature, 442, 2006
6JKN
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BU of 6jkn by Molmil
Crystal Structure of G-quadruplex Formed by Bromo-substituted Human Telomeric DNA
分子名称: DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*(BGM)P*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*(BGM)P*G)-3'), POTASSIUM ION
著者Geng, Y, Cai, Q, Liu, C, Zhu, G.
登録日2019-03-01
公開日2019-04-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA.
Nucleic Acids Res., 47, 2019
6KVG
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BU of 6kvg by Molmil
The solution structure of human Orc6
分子名称: Origin recognition complex subunit 6
著者Liu, C, Xu, N, You, Y, Zhu, G.
登録日2019-09-04
公開日2020-09-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA.
Nucleic Acids Res., 48, 2020
5ZXV
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BU of 5zxv by Molmil
Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
分子名称: MERS-CoV RBD, heavy chain, light chain
著者Zhang, S, Wang, X.
登録日2018-05-21
公開日2018-07-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (4.482 Å)
主引用文献Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
5YY5
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BU of 5yy5 by Molmil
Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ...
著者Zhang, S, Wang, P, Zhou, P, Wang, X, Zhang, L.
登録日2017-12-08
公開日2018-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
5Y3X
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BU of 5y3x by Molmil
Crystal structure of endo-1,4-beta-xylanase from Caldicellulosiruptor owensensis
分子名称: Beta-xylanase
著者Liu, X, Sun, L.C, Zhang, Y.B, Liu, T.F, Xin, F.J.
登録日2017-07-31
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insights into the Thermophilic Adaption Mechanism of Endo-1,4-beta-Xylanase from Caldicellulosiruptor owensensis.
J. Agric. Food Chem., 66, 2018
6A67
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BU of 6a67 by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLD21.140 Heavy Chain, FLD21.140 Light Chain, ...
著者Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X.
登録日2018-06-26
公開日2018-08-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies.
J. Biol. Chem., 293, 2018
5YYF
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BU of 5yyf by Molmil
Crystal structure of AF9 YEATS domain in complex with a peptide inhibitor "PHQ-H3(Q5-K9)" modified at K9 with 2-furancarboyl group
分子名称: 2-FUROIC ACID, Peptide inhibitor PHQ-H3(Q5-K9), Protein AF-9, ...
著者Li, Y, Li, H.
登録日2017-12-09
公開日2018-11-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking.
Nat. Chem. Biol., 14, 2018
7XMX
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BU of 7xmx by Molmil
Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three F61 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F61 heavy chain, F61 light chain, ...
著者Wang, X, Li, X.
登録日2022-04-27
公開日2022-11-23
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7XMZ
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BU of 7xmz by Molmil
Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three D2 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ...
著者Wang, X, Li, X.
登録日2022-04-27
公開日2022-11-23
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7XST
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BU of 7xst by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike glycoprotein in complex with three F61 Fab and three D2 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ...
著者Wang, X, Li, X.
登録日2022-05-15
公開日2022-11-23
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7XS8
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BU of 7xs8 by Molmil
Crystal structure of SARS-CoV-2 spike receptor binding domain bound with P5S-1H1 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P5S-1H1 Heavy chain, P5S-1H1 Light chain, ...
著者Wang, X, Wang, Z.
登録日2022-05-13
公開日2023-04-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants.
Nat.Immunol., 24, 2023
7XED
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BU of 7xed by Molmil
Crystal Structure of OsCIE1-Ubox and OsUBC8 complex
分子名称: U-box domain-containing protein 12, UBC core domain-containing protein
著者Zhang, Y, Yu, C.Z.
登録日2022-03-30
公開日2023-10-04
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Release of a ubiquitin brake activates OsCERK1-triggered immunity in rice.
Nature, 629, 2024
7V7M
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BU of 7v7m by Molmil
crystal structure of SARS-CoV-2 3CL protease
分子名称: 3C-like proteinase
著者Yi, Y, Zhang, M, Ye, M.
登録日2021-08-21
公開日2022-06-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Schaftoside inhibits 3CL pro and PL pro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19.
Acta Pharm Sin B, 12, 2022
7WRP
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BU of 7wrp by Molmil
Crystal Structure of pks13-ACP domain from Corynebacterium diphtheriae
分子名称: 4'-PHOSPHOPANTETHEINE, Polyketide synthase involved in mycolic acid biosynthesis
著者Liu, X.
登録日2022-01-27
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献Crystal structures of FadD32 and pks13-ACP domain from Corynebacterium diphtheriae.
Biochem.Biophys.Res.Commun., 590, 2022
2FAT
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BU of 2fat by Molmil
An anti-urokinase plasminogen activator receptor (UPAR) antibody: Crystal structure and binding epitope
分子名称: FAB ATN-615, heavy chain, light chain
著者Li, Y, Parry, G, Shi, X, Chen, L, Callahan, J.A, Mazar, A.P, Huang, M.
登録日2005-12-07
公開日2006-11-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献An anti-urokinase plasminogen activator receptor (uPAR) antibody: crystal structure and binding epitope
J.Mol.Biol., 365, 2007
7X2M
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BU of 7x2m by Molmil
Crystal structure of nanobody 1-2C7 with SARS-CoV-2 RBD
分子名称: 1-2C7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1
著者Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X.
登録日2022-02-25
公開日2022-12-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
7X2L
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BU of 7x2l by Molmil
Crystal structure of nanobody 3-2A2-4 with SARS-CoV-2 RBD
分子名称: Nanobody 3-2A2-4, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X.
登録日2022-02-25
公開日2022-12-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
7X2J
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BU of 7x2j by Molmil
Crystal structure of nanobody Nb70 with SARS-CoV RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nb70, Spike protein S1
著者Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X.
登録日2022-02-25
公開日2022-12-21
最終更新日2023-06-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
7X2K
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BU of 7x2k by Molmil
Crystal structure of nanobody Nb70 with antibody 1F11 fab and SARS-CoV-2 RBD
分子名称: 1F11-H, 1F11-L, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, X.Q, Zhang, L.Q, Ren, Y.F, Li, M.X.
登録日2022-02-25
公開日2022-12-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses.
Nat Commun, 13, 2022
5YF8
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Crystals structure of Classical swine fever virus NS5B (residues 1-672, Y471A-E472A mutant)
分子名称: ACETATE ION, RdRp catalytic
著者Liu, W, Gong, P.
登録日2017-09-20
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.396 Å)
主引用文献A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase.
Nucleic Acids Res., 46, 2018
5YF6
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Crystals structure of Classical swine fever virus NS5B (residues 1-682)
分子名称: RdRp catalytic
著者Liu, W, Gong, P.
登録日2017-09-20
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase.
Nucleic Acids Res., 46, 2018
5YF7
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BU of 5yf7 by Molmil
Crystals structure of Classical swine fever virus NS5B (residues 1-672)
分子名称: RdRp catalytic
著者Liu, W, Gong, P.
登録日2017-09-20
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase.
Nucleic Acids Res., 46, 2018
5YF5
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Crystals structure of Classical swine fever virus NS5B (residues 1-694)
分子名称: RdRp catalytic
著者Liu, W, Gong, P.
登録日2017-09-20
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase.
Nucleic Acids Res., 46, 2018

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