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6O7I
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BU of 6o7i by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6OV0
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BU of 6ov0 by Molmil
Crystal structure of Csm6 in complex with A4>p by soaking A4>p into Csm6
分子名称: RNA (5'-R(*AP*AP*AP*(A23))-3'), Uncharacterized protein
著者Jia, N, Patel, D.J.
登録日2019-05-06
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6UFJ
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BU of 6ufj by Molmil
Pistol ribozyme product crystal structure
分子名称: MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*AP*G)-3'), RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(23G))-3'), ...
著者Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
登録日2019-09-24
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
6UEY
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BU of 6uey by Molmil
Pistol ribozyme transition-state analog vanadate
分子名称: MAGNESIUM ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER)
著者Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
登録日2019-09-23
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
6UFK
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BU of 6ufk by Molmil
Pistol ribozyme product crystal soaked in Mn2+
分子名称: MANGANESE (II) ION, RNA (5'-R(*UP*CP*CP*AP*G)-3'), RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(23G))-3'), ...
著者Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
登録日2019-09-24
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
3QLC
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BU of 3qlc by Molmil
Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide
分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
著者Li, H, Patel, D.J.
登録日2011-02-02
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QLN
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Crystal structure of ATRX ADD domain in free state
分子名称: Transcriptional regulator ATRX, ZINC ION
著者Li, H, Patel, D.J.
登録日2011-02-03
公開日2011-06-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
6V9Q
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BU of 6v9q by Molmil
Cryo-EM structure of Cascade-TniQ binary complex
分子名称: Cas8, RNA (61-MER), TniQ family protein, ...
著者Jia, N, Patel, D.J.
登録日2019-12-15
公開日2020-01-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex.
Cell Res., 30, 2020
6VBW
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BU of 6vbw by Molmil
Cryo-EM structure of Cascade-TniQ-dsDNA ternary complex
分子名称: Cas6, Cas7, Cas8, ...
著者Jia, N, Patel, D.J.
登録日2019-12-19
公開日2020-01-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex.
Cell Res., 30, 2020
6V9P
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BU of 6v9p by Molmil
Crystal structure of the transposition protein TniQ
分子名称: GLYCEROL, TniQ family protein, ZINC ION
著者Jia, N, Patel, D.J.
登録日2019-12-14
公開日2020-01-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex.
Cell Res., 30, 2020
6VRB
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BU of 6vrb by Molmil
Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex
分子名称: AcrVIA1, CRISPR-associated endoribonuclease Cas13a, RNA (52-MER)
著者Jia, N, Meeske, A.J, Marraffini, L.A, Patel, D.J.
登録日2020-02-07
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity.
Science, 369, 2020
6VRC
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BU of 6vrc by Molmil
Cryo-EM structure of Cas13(crRNA)
分子名称: CRISPR-associated endoribonuclease Cas13a, RNA (51-MER)
著者Jia, N, Meeske, A.J, Marraffini, L.A, Patel, D.J.
登録日2020-02-07
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity.
Science, 369, 2020
6WXY
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BU of 6wxy by Molmil
crystal structure of cA6-bound Card1
分子名称: Card1, cA6
著者Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
登録日2020-05-12
公開日2020-12-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
6WXW
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BU of 6wxw by Molmil
crystal structure of apo Card1
分子名称: Card1
著者Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
登録日2020-05-12
公開日2020-12-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
6WXX
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BU of 6wxx by Molmil
crystal structure of cA4-activated Card1
分子名称: Card1, MANGANESE (II) ION, cA4
著者Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
登録日2020-05-12
公開日2020-12-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
5BS7
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BU of 5bs7 by Molmil
Structure of histone H3/H4 in complex with Spt2
分子名称: Histone H3.2, Histone H4, Protein SPT2 homolog, ...
著者Chen, S, Patel, D.J.
登録日2015-06-01
公開日2015-07-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2.
Genes Dev., 29, 2015
5BNV
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BU of 5bnv by Molmil
Crystal structure of Human MCM2 HBD chaperoning a histone H3-H4 tetramer
分子名称: DNA replication licensing factor MCM2, Histone H3.3, Histone H4, ...
著者Huang, H, Patel, D.J.
登録日2015-05-26
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
5DET
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BU of 5det by Molmil
X-ray structure of human RBPMS in complex with the RNA
分子名称: RNA (5'-R(*UP*CP*AP*C)-3'), RNA (5'-R(P*UP*CP*AP*CP*U)-3'), RNA-binding protein with multiple splicing, ...
著者Teplova, M, Farazi, T.A, Tuschl, T, Patel, D.J.
登録日2015-08-25
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS.
Q. Rev. Biophys., 49, 2016
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
分子名称: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
著者Chen, S, Patel, D.J.
登録日2015-08-19
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
5DAG
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BU of 5dag by Molmil
Crystal structure of PZP domain of human AF10 protein
分子名称: Protein AF-10, ZINC ION
著者Chen, S, Patel, D.J.
登録日2015-08-19
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
5DDQ
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BU of 5ddq by Molmil
L-glutamine riboswitch bound with L-glutamine soaked with Mn2+
分子名称: GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ...
著者Ren, A, Patel, D.J.
登録日2015-08-25
公開日2015-12-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDR
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BU of 5ddr by Molmil
L-glutamine riboswitch bound with L-glutamine soaked with Cs+
分子名称: CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ...
著者Ren, A, Patel, D.J.
登録日2015-08-25
公開日2015-12-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.605 Å)
主引用文献Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DE8
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BU of 5de8 by Molmil
Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form.
分子名称: Fragile X mental retardation protein 1, IRIDIUM HEXAMMINE ION, POTASSIUM ION, ...
著者Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
登録日2015-08-25
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.1003 Å)
主引用文献Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
4DOV
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BU of 4dov by Molmil
Structure of free mouse ORC1 BAH domain
分子名称: Origin recognition complex subunit 1
著者Song, J, Patel, D.J.
登録日2012-02-10
公開日2012-03-07
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Nature, 484, 2012
5DEA
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BU of 5dea by Molmil
Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, cesium bound form.
分子名称: CESIUM ION, Fragile X mental retardation protein 1, POTASSIUM ION, ...
著者Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
登録日2015-08-25
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7973 Å)
主引用文献Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015

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