7WNH
 
 | | Crystal structure of Nurr1 binding to NBRE | | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), Nuclear receptor subfamily 4 group A member 2, ... | | 著者 | Zhao, M, Xu, T, Wang, N, Guo, Y, Liu, J. | | 登録日 | 2022-01-18 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXR alpha heterodimer.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7CHU
 | | Geobacillus virus E2 - ORF18 | | 分子名称: | Putative pectin lyase | | 著者 | Gong, Y. | | 登録日 | 2020-07-06 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.008 Å) | | 主引用文献 | Structural and functional characterization of the deep-sea thermophilic bacteriophage GVE2 tailspike protein.
Int.J.Biol.Macromol., 164, 2020
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7DAT
 | | The crystal structure of COVID-19 main protease treated by AF | | 分子名称: | COVID-19 MAIN PROTEASE, GOLD ION | | 著者 | He, Z.S, He, B, Cao, P, Jiang, H.D, Gong, Y, Gao, X.Y. | | 登録日 | 2020-10-18 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A comparison of Remdesivir versus gold cluster in COVID-19 animal model: A better therapeutic outcome of gold cluster.
Nano Today, 44, 2022
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7DAV
 | | The native crystal structure of COVID-19 main protease | | 分子名称: | COVID-19 MAIN PROTEASE | | 著者 | He, Z.S, He, B, Cao, P, Jiang, H.D, Gong, Y, Gao, X.Y. | | 登録日 | 2020-10-18 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | A comparison of Remdesivir versus gold cluster in COVID-19 animal model: A better therapeutic outcome of gold cluster.
Nano Today, 44, 2022
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7DAU
 | | The crystal structure of COVID-19 main protease treated by GA | | 分子名称: | COVID-19 MAIN PROTEASE, GOLD ION | | 著者 | He, Z.S, He, B, Cao, P, Jiang, H.D, Gong, Y, Gao, X.Y. | | 登録日 | 2020-10-18 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | A comparison of Remdesivir versus gold cluster in COVID-19 animal model: A better therapeutic outcome of gold cluster.
Nano Today, 44, 2022
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7V55
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7V53
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8HQL
 | | Crystal structure of mouse SNX25 PX domain | | 分子名称: | ACETIC ACID, CHLORIDE ION, GLYCEROL, ... | | 著者 | Yu, Z, Xu, J, Liu, J. | | 登録日 | 2022-12-13 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Redox-modulated SNX25 as a novel regulator of GPCR-G protein signaling from endosomes.
Redox Biol, 75, 2024
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7DYM
 | | Pseudomonas aeruginosa TseT-TsiT complex | | 分子名称: | Imm52 domain-containing protein, Tox-REase-5 domain-containing protein | | 著者 | She, Z. | | 登録日 | 2021-01-22 | | 公開日 | 2021-08-25 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure and SAXS studies unveiled a novel inhibition mechanism of the Pseudomonas aeruginosa T6SS TseT-TsiT complex.
Int.J.Biol.Macromol., 188, 2021
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7WF9
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7WDK
 | | The structure of PldA-PA3488 complex | | 分子名称: | Phospholipase D, Tli4_C domain-containing protein | | 著者 | Zhao, L, Yang, X.Y, Li, Z.Q. | | 登録日 | 2021-12-21 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural insights into PA3488-mediated inactivation of Pseudomonas aeruginosa PldA
Nat Commun, 13, 2022
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7WF8
 | | Crystal structure of mouse SNX25 RGS domain in space group P212121 | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Zhang, Y, Xu, J, Liu, J. | | 登録日 | 2021-12-26 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins.
J.Mol.Biol., 434, 2022
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7WF6
 | | Crystal structure of SNX13 RGS domain | | 分子名称: | CHLORIDE ION, Sorting nexin-13 | | 著者 | Xu, J, Zhu, J, Liu, J. | | 登録日 | 2021-12-26 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins.
J.Mol.Biol., 434, 2022
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7FFT
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7FFW
 | | The crystal structure of a domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, METHOXYETHANE, ... | | 著者 | Wang, L, Bu, T, Bai, X. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of the domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica.
Acta Crystallogr D Struct Biol, 78, 2022
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6LCH
 | | Pseudomonas aeruginosa 5086 (PA5086) | | 分子名称: | Sel1 repeat family protein | | 著者 | She, Z, Geng, Z. | | 登録日 | 2019-11-19 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | | 主引用文献 | Characterization of the Pseudomonas aeruginosa T6SS PldB immunity proteins PA5086, PA5087 and PA5088 explains a novel stockpiling mechanism.
Acta Crystallogr.,Sect.F, 76, 2020
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8HDL
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8IFO
 | | Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter | | 分子名称: | DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3'), Estrogen-related receptor gamma, ... | | 著者 | Xu, T, Zhen, X, Liu, J. | | 登録日 | 2023-02-19 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element.
Biochem.Biophys.Res.Commun., 656, 2023
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8IOY
 | | Structure of ATP7B C983S/C985S/D1027A mutant with AMP-PNP | | 分子名称: | Copper-transporting ATPase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Yang, G, Xu, L, Guo, J, Wu, Z. | | 登録日 | 2023-03-13 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
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7USI
 | | BRD2-BD1 in complex with MDP5 | | 分子名称: | (8M)-8-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(morpholin-4-yl)-4H-1-benzopyran-4-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 2, ... | | 著者 | Jayasinghe, T.D, Ronning, D.R. | | 登録日 | 2022-04-25 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma.
J Control Release, 354, 2023
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7USH
 | | BRD2-BD2 in complex with SF2523 | | 分子名称: | 1,2-ETHANEDIOL, 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one, Bromodomain-containing protein 2 | | 著者 | Jayasinghe, T.D, Ronning, D.R. | | 登録日 | 2022-04-25 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma.
J Control Release, 354, 2023
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7USG
 | | BRD2-BD2 in complex with MDP5 | | 分子名称: | (8M)-8-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(morpholin-4-yl)-4H-1-benzopyran-4-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 2, ... | | 著者 | Jayasinghe, T.D, Ronning, D.R. | | 登録日 | 2022-04-25 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma.
J Control Release, 354, 2023
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7USK
 | | BRD4-BD2 Ligand free | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE | | 著者 | Jayasinghe, T.D, Ronning, D.R. | | 登録日 | 2022-04-25 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma.
J Control Release, 354, 2023
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7DRG
 | | Pseudomonas aeruginosa T6SS protein PA0821 | | 分子名称: | PA0821 | | 著者 | She, Z. | | 登録日 | 2020-12-28 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Pseudomonas aeruginosa PAAR2 cluster encodes a putative VRR-NUC domain-containing effector.
Febs J., 288, 2021
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7USJ
 | | BRD4-BD2 in complex with SF2523 | | 分子名称: | 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one, Bromodomain-containing protein 4 | | 著者 | Jayasinghe, T.D, Ronning, D.R. | | 登録日 | 2022-04-25 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma.
J Control Release, 354, 2023
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