7NBW
 
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6HFW
 | | Mycobacterium tuberculosis DprE1 in complex with CMP1 | | 分子名称: | 8-(oxidanylamino)-2-piperidin-1-yl-6-(trifluoromethyl)-1,3-benzothiazin-4-one, Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Chung, C. | | 登録日 | 2018-08-21 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.
Sci Rep, 8, 2018
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6HFV
 | | Mycobacterium tuberculosis DprE1 in complex with CMP2 | | 分子名称: | 8-(oxidanylamino)-2-piperidin-1-yl-6-(trifluoromethyl)-1,3-benzothiazin-4-one, Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Chung, C. | | 登録日 | 2018-08-21 | | 公開日 | 2018-09-19 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.
Sci Rep, 8, 2018
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4A9M
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-cyclopentyl-5-(3,5- dimethyl-1,2-oxazol-4-yl)-2-methylbenzene-1-sulfonamide | | 分子名称: | BROMODOMAIN CONTAINING 2, N-cyclopentyl-5-(3,5-dimethylisoxazol-4-yl)-2-methylbenzenesulfonamide, SULFATE ION | | 著者 | Chung, C, Bamborough, P. | | 登録日 | 2011-11-26 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides.
J.Med.Chem., 55, 2012
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4A9N
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-cyclopropyl-5-(3,5- dimethyl-1,2-oxazol-4-yl)-2-methylbenzene-1-sulfonamide | | 分子名称: | 1,2-ETHANEDIOL, BROMODOMAIN CONTAINING 2, DIMETHYL SULFOXIDE, ... | | 著者 | Chung, C, Bamborough, P. | | 登録日 | 2011-11-26 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides.
J.Med.Chem., 55, 2012
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4A9E
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3-methyl-1,2,3,4- tetrahydroquinazolin-2-one | | 分子名称: | 1,2-ETHANEDIOL, 3-methyl-3,4-dihydroquinazolin-2(1H)-one, BROMODOMAIN-CONTAINING PROTEIN 2, ... | | 著者 | Chung, C, Bamborough, P. | | 登録日 | 2011-11-26 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Fragment-Based Discovery of Bromodomain Inhibitors Part 1: Inhibitor Binding Modes and Implications for Lead Discovery.
J.Med.Chem., 55, 2012
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5OO5
 | | Streptomyces PAC13 with uridine uronic acid | | 分子名称: | Putative cupin_2 domain-containing isomerase, uridine uronic acid | | 著者 | Chung, C, Michailidou, F. | | 登録日 | 2017-08-05 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5OOA
 | | Streptomyces PAC13 (Y89F) with uridine | | 分子名称: | Putative cupin_2 domain-containing isomerase, URIDINE | | 著者 | Chung, C, Michailidou, F. | | 登録日 | 2017-08-06 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5OO4
 | | Streptomyces PAC13 with uridine | | 分子名称: | Putative cupin_2 domain-containing isomerase, URIDINE | | 著者 | Chung, C, Michailidou, F. | | 登録日 | 2017-08-05 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5OO8
 | | Streptomyces PAC13 (H42Q) with uridine | | 分子名称: | 1,2-ETHANEDIOL, Putative cupin_2 domain-containing isomerase, URIDINE | | 著者 | Chung, C, Michailidou, F. | | 登録日 | 2017-08-06 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5OO9
 | | Streptomyces PAC13 (Y55F) with uridine | | 分子名称: | Putative cupin_2 domain-containing isomerase, URIDINE | | 著者 | Chung, C, Michailidou, F. | | 登録日 | 2017-08-06 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.
Angew. Chem. Int. Ed. Engl., 56, 2017
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1HRJ
 | | HUMAN RANTES, NMR, 13 STRUCTURES | | 分子名称: | HUMAN REGULATED UPON ACTIVATION NORMAL T-CELL EXPRESSED AND SECRETED | | 著者 | Chung, C, Cooke, R.M, Proudfoot, A.E.I, Wells, T.N.C. | | 登録日 | 1995-08-18 | | 公開日 | 1996-10-14 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The three-dimensional solution structure of RANTES.
Biochemistry, 34, 1995
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3BC5
 | | X-ray crystal structure of human ppar gamma with 2-(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-2-phenyl-2h-1,2,3-triazol-4-yl)acetic acid | | 分子名称: | (5-{3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]benzyl}-2-phenyl-2H-1,2,3-triazol-4-yl)acetic acid, Peroxisome proliferator-activated receptor gamma | | 著者 | Muckelbauer, J.K. | | 登録日 | 2007-11-12 | | 公開日 | 2008-11-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists.
Bioorg.Med.Chem.Lett., 19, 2009
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8W9C
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8W9D
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8W9F
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8W9E
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8HPO
 | | Cryo-EM structure of a SIN3/HDAC complex from budding yeast | | 分子名称: | Histone deacetylase RPD3, PHOSPHOTHREONINE, POTASSIUM ION, ... | | 著者 | Guo, Z, Zhan, X, Wang, C. | | 登録日 | 2022-12-12 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structure of a SIN3-HDAC complex from budding yeast.
Nat.Struct.Mol.Biol., 30, 2023
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8I02
 | | Cryo-EM structure of the SIN3S complex from S. pombe | | 分子名称: | Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ... | | 著者 | Wang, C, Guo, Z, Zhan, X. | | 登録日 | 2023-01-10 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Two assembly modes for SIN3 histone deacetylase complexes.
Cell Discov, 9, 2023
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8I03
 | | Cryo-EM structure of the SIN3L complex from S. pombe | | 分子名称: | Chromatin modification-related protein png2, Histone deacetylase clr6, POTASSIUM ION, ... | | 著者 | Wang, C, Guo, Z, Zhan, X. | | 登録日 | 2023-01-10 | | 公開日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Two assembly modes for SIN3 histone deacetylase complexes.
Cell Discov, 9, 2023
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4E2K
 | | The structure of the S. aureus DnaG RNA Polymerase Domain | | 分子名称: | BENZAMIDINE, DNA primase | | 著者 | Rymer, R.U, Solorio, F.A, Clement, C, Corn, J.E, Wang, J.D, Berger, J.M. | | 登録日 | 2012-03-08 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
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7E77
 | | The structure of cytosolic TaPGI | | 分子名称: | Glucose-6-phosphate isomerase | | 著者 | Gao, F, Liu, C.M. | | 登録日 | 2021-02-25 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
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7E78
 | | the structure of cytosolic TaPGI with substrate | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, Glucose-6-phosphate isomerase | | 著者 | Gao, F, Liu, C.M. | | 登録日 | 2021-02-25 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
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7E76
 | | The structure of chloroplastic TaPGI | | 分子名称: | Glucose-6-phosphate isomerase | | 著者 | Gao, F, Liu, C.M. | | 登録日 | 2021-02-25 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
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7X9B
 | | Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Tang, T, Han, S, Zhao, Q, Wu, B. | | 登録日 | 2022-03-15 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
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