6HFW

Mycobacterium tuberculosis DprE1 in complex with CMP1

Summary for 6HFW

• Entry DOI: 10.2210/pdb6hfw/pdb
• Descriptor: Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ... (5 entities in total)
• Functional Keywords: oxidoreductase, oxidoreductase inhibitor
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 2
• Total formula weight: 106008.19

Authors

Chung, C. (deposition date: 2018-08-21, release date: 2018-09-19)

• Primary citation: Richter, A.,Rudolph, I.,Mollmann, U.,Voigt, K.,Chung, C.W.,Singh, O.M.P.,Rees, M.,Mendoza-Losana, A.,Bates, R.,Ballell, L.,Batt, S.,Veerapen, N.,Futterer, K.,Besra, G.,Imming, P.,Argyrou, A.; Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.; Sci Rep, 8:13473-13473, 2018; PubMed: 30194385; DOI: 10.1038/s41598-018-31316-6

Experimental method

X-RAY DIFFRACTION (2.47 Å)