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5VE6
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Crystal structure of Sugen kinase 223
分子名称: Tyrosine-protein kinase SgK223
著者Patel, O, Lucet, I, Panjikar, S.
登録日2017-04-03
公開日2017-10-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.953 Å)
主引用文献Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association.
Nat Commun, 8, 2017
2V91
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STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH STRICTOSIDINE
分子名称: METHYL (2S,3R,4S)-3-ETHYL-2-(BETA-D-GLUCOPYRANOSYLOXY)-4-[(1S)-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLIN-1-YLMETHYL]-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE, STRICTOSIDINE SYNTHASE
著者Loris, E.A, Panjikar, S, Ruppert, M, Barleben, L, Unger, M, Stoeckigt, J.
登録日2007-08-16
公開日2008-09-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structure Based Engineering of Strictosidine Synthase: Auxiliary for Alkaloid Libraries
Chem.Biol., 14, 2007
7E4M
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Class I Pimarane-Type Diterpene Synthases Stt4548
分子名称: Stt4548
著者Yu, J.H, Xing, B.Y, Ma, M.
登録日2021-02-14
公開日2021-10-06
最終更新日2022-04-20
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis
Commun Chem, 4, 2021
7E4O
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Class I Pimarane-Type Diterpene Synthases from Actinomycetes
分子名称: Sat1646
著者Yu, J.H, Xing, B.Y, Ma, M.
登録日2021-02-14
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis
Commun Chem, 4, 2021
7E4N
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Crystal structure of Sat1646
分子名称: MAGNESIUM ION, Sat1646
著者Yu, J.H, Xing, B.Y, Ma, M.
登録日2021-02-14
公開日2021-10-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis
Commun Chem, 4, 2021
7DW9
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Cryo-EM structure of human V2 vasopressin receptor in complex with an Gs protein
分子名称: CHOLESTEROL, CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhou, F, Jiang, Y.
登録日2021-01-15
公開日2021-07-21
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of ligand recognition and activation of human V2 vasopressin receptor.
Cell Res., 31, 2021
7EO0
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FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY C4
分子名称: Ig heavy chain variable region, Ig lamda chain variable region, O/TIBET/99 VP1, ...
著者He, Y, Li, K.
登録日2021-04-21
公開日2021-08-18
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Two Cross-Protective Antigen Sites on Foot-and-Mouth Disease Virus Serotype O Structurally Revealed by Broadly Neutralizing Antibodies from Cattle.
J.Virol., 95, 2021
5YA2
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Crystal structure of LsrK-HPr complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Autoinducer-2 kinase, HEXANE-1,6-DIOL, ...
著者Ryu, K.S, Ha, J.H.
登録日2017-08-30
公開日2018-07-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
Sci Adv, 4, 2018
5YA1
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crystal structure of LsrK-HPr complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Autoinducer-2 kinase, HEXANE-1,6-DIOL, ...
著者Ryu, K.S, Ha, J.H.
登録日2017-08-29
公開日2018-07-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
Sci Adv, 4, 2018
5YA0
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Crystal structure of LsrK and HPr complex
分子名称: Autoinducer-2 kinase, HEXANE-1,6-DIOL, PHOSPHATE ION, ...
著者Ryu, K.S, Ha, J.H.
登録日2017-08-29
公開日2018-07-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
Sci Adv, 4, 2018
7WGR
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Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase (E1) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex
分子名称: 2-oxoglutarate dehydrogenase, mitochondrial, CALCIUM ION, ...
著者Yu, X, Yang, W, Zhong, Y.H, Ma, X.M, Gao, Y.Z.
登録日2021-12-28
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Structural basis for the activity and regulation of human alpha-ketoglutarate dehydrogenase revealed by Cryo-EM
Biochem.Biophys.Res.Commun., 602, 2022
8H7Z
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Cryo-EM structure of SARS-CoV-2 BA.2 RBD in complex with BA7535 fab (local refinement)
分子名称: BA7535 fab, Spike glycoprotein
著者Liu, Z, Yan, A, Gao, Y.
登録日2022-10-21
公開日2023-08-30
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants.
Nat Commun, 15, 2024
8H7L
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Cryo-EM Structure of SARS-CoV-2 BA.2 Spike protein in complex with BA7535
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7535 fab heavt chain, ...
著者Liu, Z, Yan, A, Gao, Y.
登録日2022-10-20
公開日2023-08-30
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants.
Nat Commun, 15, 2024
7CBZ
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Crystal structure of T2R-TTL-A31 complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-[2-[4-(2-cyclopropylethanoyl)piperazin-1-yl]ethoxy]phenyl]pyridin-2-yl]-N-(phenylmethyl)ethanamide, CALCIUM ION, ...
著者Yang, J.H, Yan, W.
登録日2020-06-15
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure.
J.Med.Chem., 64, 2021
7CR8
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BU of 7cr8 by Molmil
Synechocystis Cas1-Cas2-prespacerL complex
分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 1, DNA (36-MER)
著者Yu, Y, Chen, Q.
登録日2020-08-12
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis.
Nucleic Acids Res., 49, 2021
7XDA
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BU of 7xda by Molmil
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with BA7208 and BA7125 fab (local refinement)
分子名称: BA7125 fab, BA7208 fab, Spike glycoprotein
著者Liu, Z, Liu, S, Liu, S.
登録日2022-03-26
公開日2023-03-01
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
7XDB
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Cryo-EM structure of SARS-CoV-2 Omicron Spike protein in complex with BA7208 fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7208 fab, ...
著者Liu, Z, Liu, S, Gao, Y.Z.
登録日2022-03-26
公開日2023-03-01
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
7XCZ
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BU of 7xcz by Molmil
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with BA7054 and BA7125 fab (local refinement)
分子名称: BA7054 fab, BA7125 fab, Spike glycoprotein
著者Liu, Z, Liu, S.
登録日2022-03-26
公開日2023-03-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
5K9A
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BU of 5k9a by Molmil
Sortase A from Corynebacterium diphtheriae
分子名称: Putative fimbrial associated sortase-like protein, SULFATE ION
著者Osipiuk, J, Huang, I.-H, Ma, X, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-05-31
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking.
Proc.Natl.Acad.Sci.USA, 115, 2018
6J1M
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Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl covalent to C166
分子名称: 1,2-ETHANEDIOL, 3-oxopentanedioic acid, A. acutangulus PKS2
著者Fang, C.L, Zhang, Y.
登録日2018-12-28
公開日2019-09-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.
Nat Commun, 10, 2019
6J1N
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Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl-CoA
分子名称: (3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,19,21-tetraoxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide (non-preferred name), A. acutangulus PKS2
著者Fang, C.L, Zhang, Y.
登録日2018-12-28
公開日2019-09-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.532 Å)
主引用文献Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.
Nat Commun, 10, 2019
7VC8
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Complex structure of AtHPPD with inhibitor PYQ3
分子名称: 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, pyren-1-yl 2-[1,5-dimethyl-2,4-bis(oxidanylidene)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazolin-3-yl]ethanoate
著者Yang, G.F, Lin, H.Y.
登録日2021-09-01
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.606 Å)
主引用文献Design of an HPPD fluorescent probe and visualization of plant responses to abiotic stress
Adv Agrochem, 2022
7WJ8
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Complex structure of AtHPPD-PyQ1
分子名称: 2-pyren-1-yloxyethyl 2-[1,5-dimethyl-2,4-bis(oxidanylidene)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazolin-3-yl]ethanoate, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Yang, G.-F, Lin, H.-Y, Dong, J.
登録日2022-01-05
公開日2022-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Design of an HPPD fluorescent probe and visualization of plant responses to abiotic stress
Adv Agrochem, 2022
7WJJ
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Complex structure of AtHPPD-PyQ2
分子名称: 2-[1,5-dimethyl-2,4-bis(oxidanylidene)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazolin-3-yl]-N-(2-pyren-1-yloxyethyl)ethanamide, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Yang, G.-F, Lin, H.-Y, Dong, J.
登録日2022-01-06
公開日2022-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Design of an HPPD fluorescent probe and visualization of plant responses to abiotic stress
Adv Agrochem, 2022
8KG6
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Yeast replisome in state I
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023

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