7WGR

Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase (E1) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex

Summary for 7WGR

• Entry DOI: 10.2210/pdb7wgr/pdb
• EMDB information: 32485
• Descriptor: 2-oxoglutarate dehydrogenase, mitochondrial, CALCIUM ION, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: mitochondria, ketoglutarate dehydrogenase, single-particle cryoem, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 204991.91

Authors

Yu, X.,Yang, W.,Zhong, Y.H.,Ma, X.M.,Gao, Y.Z. (deposition date: 2021-12-28, release date: 2022-06-01, Last modification date: 2024-06-26)

• Primary citation: Zhong, Y.,Gao, Y.,Zhou, D.,Ma, X.,Chen, H.,Xu, Y.,Yang, W.,Yu, X.; Structural basis for the activity and regulation of human alpha-ketoglutarate dehydrogenase revealed by Cryo-EM; Biochem.Biophys.Res.Commun., 602:120-126, 2022; DOI: 10.1016/j.bbrc.2022.02.093

Experimental method

ELECTRON MICROSCOPY (2.92 Å)